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Karuniawati , Hidayah
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Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Nursing Public Health

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Pengaruh Pengambilan Keputusan Bersama terhadap Kadar Glukosa dan HbA1c pada Pasien Diabetes Mellitus: Tinjauan Literatur Hilmawati, Febriana; Karuniawati , Hidayah
Journal of Pharmaceutical and Sciences JPS Volume 8 Nomor 3 (2025)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v8i3.1008

Abstract

Background: Diabetes mellitus (DM) is a chronic disease with a high global prevalence, requiring comprehensive and patient-centered care. Shared Decision Making (SDM) is a collaborative approach between patients and healthcare providers that has been associated with improved treatment adherence and clinical outcomes in chronic diseases. Objective: This literature review aimed to evaluate the impact of SDM on glycemic control, particularly blood glucose and HbA1c levels, in patients with diabetes mellitus. Methods: A systematic search was conducted on PubMed and Scopus databases using specific keywords, limited to randomized controlled trials (RCTs) published in English between 2015 and 2025. Inclusion criteria included adult patients with type 1 or type 2 DM, SDM as the primary intervention, and HbA1c or blood glucose levels as clinical outcomes. Results: Five RCTs met the eligibility criteria. Most studies reported a decrease in HbA1c in the intervention group, although only one study showed a statistically significant within-group reduction. No consistent significant differences were observed between the intervention and control groups. However, SDM was positively associated with improved patient engagement, satisfaction, and the quality of communication. Conclusion: While evidence regarding the direct impact of SDM on HbA1c remains inconclusive, SDM appears to enhance patient participation and therapeutic communication in diabetes care. Further standardized and long-term studies are needed to confirm its clinical effectiveness.
Evaluasi Adverse Drug Reaction pada Pasien Tuberkulosis Anak di Puskesmas Kabupaten Tegal Bariyah, Fathatul; Karuniawati , Hidayah
Journal of Pharmaceutical and Sciences JPS Volume 8 Nomor 4 (2025)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v8i4.1157

Abstract

Tuberculosis (TB) is a disease caused by bacteria, namely Mycobacterium tuberculosis (MTB) and needanti-TB drugs (ATD) treatment. The success of ATD therapy is influenced by various factors, including ADRs and their management, which play a role in treatment and retention in care. The frequency and severity of ADRs caused by ATD are always a concern, especially in children. The study aims to determine the prevalence of ADRs, determine the management and outcome of ADR treatment in pediatric TB patients at the Tegal Regency Community Health Center. This study used a cross-sectional design in  pediatric TB patients aged 0-18 years. This study showed The most frequent ADRs were gastrointestinal disturbances (16.7%), joint pain (8.3%), peripheral neuropathy (6.7%), and flu-like syndrome (6.7%). The ADR event category is likely to have a percentage of 91% of the overall number of events, followed by the possibility with a percentage of 9% of events. Management strategies, including vitamin B complex supplementation, antacids, multivitamins, probiotics, antipyretics, and topical agents, effectively reduced or eliminated ADRs. The most common ADRs werw gastrointestinal disorders, joint pain and flu syndrome. Management of ADRs related to anti-tuberculosis drugs (ATD) has been successful in reducing or eliminating ADRs. Special attention from healthcare workers should be given to patients at spesific risk groups for ADR management to improve therapy success.
Co-Authors Bariyah, Fathatul Hilmawati, Febriana