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All Journal Jurnal Pembelajaran dan Biologi Nukleus Jurnal Kesmas Jambi
Novitasari, Prima
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Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Education Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Medicine & Pharmacology Public Health

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A Comparative Review of Chitinase Enzymes from Microbial and Mammalian Origins and Their Roles in Health Applications Novitasari, Prima; Hidayanti, Maria Ulfa Nur; Karolina, Maria Estela; Nidha, Amalia An
JURNAL PEMBELAJARAN DAN BIOLOGI NUKLEUS Vol 11, No 2: Jurnal Pembelajaran Dan Biologi Nukleus June 2025
Publisher : Universitas Labuhanbatu

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36987/jpbn.v11i2.7554

Abstract

Background: Chitinase is an enzyme crucial in chitin biodegradation, breaking the 1,4-N-α-acetyl-D-glucosamine bonds of its monomers. It is produced by a wide range of organisms, from microorganisms such as bacteria and fungi to macroorganisms including humans. Chitinases have been widely studied for applications in biological control, environmental management, and medical fields, including immune modulation and infection therapy. However, there is still a research gap due to the limited number of systematic comparative studies examining the structural, genetic, and functional differences among chitinases from various biological sources. This limitation hinders optimal and targeted use of chitinases in enzyme-based technologies, particularly for medical applications. Therefore, comprehensive studies are needed not only to describe chitinases by their sources but also to evaluate their practical potential and innovative opportunities for human health. Methods: This study uses a narrative literature review approach. Articles were collected, screened, and systematically organized according to their scope, focusing on chitinase sources, mechanisms of action, and applications in healthcare. Results: The analysis shows fundamental differences in domain structure, gene expression, and catalytic mechanisms of chitinases from bacteria, fungi, and humans. Bacterial chitinases exhibit environmental stability and serve as infection biomarkers, fungal chitinases excel in immunotherapy and bioactive compound production, and human chitinases, though less explored, show potential in precision diagnostics and inflammatory therapy. Conclusions: This cross-domain comparison maps structural and functional characteristics and opens opportunities for integrating cross-species enzyme functions for innovative enzyme-based biopharmaceuticals and precision therapies addressing modern pathogens
Enhancing Childbirth Preparedness: The Effects of Prenatal Yoga on Physical nnd Mental Readiness Santoso, Ferry; Hidayanti, Maria Ulfa Nur; Damanik, Brema JK; Novitasari, Prima; Karolina, Maria Estela
Jurnal Kesmas Jambi Vol. 9 No. 2 (2025): VOLUME 9 - NUMBER 2 - July 2025
Publisher : Program Studi Ilmu Kesehatan Masyarakat, Universitas Jambi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22437/jkmj.v9i2.44732

Abstract

Childbirth requires both physical and mental readiness, yet many women face it with anxiety and insufficient preparation. Prenatal Yoga is increasingly recognized as a holistic intervention that integrates physical, psychological, and emotional preparation. This study aimed to examine the effect of Prenatal Yoga on the physical and mental readiness of pregnant women in facing childbirth. A cross-sectional quantitative study was conducted in May 2025 involving 54 pregnant women in Blora Regency. Data were collected using structured questionnaires to assess physical readiness (body flexibility and discomfort) and mental readiness (anxiety and relaxation) through the Hamilton Anxiety Rating Scale (HARS). The association between Prenatal Yoga and readiness was analyzed using Chi-Square and Fisher’s Exact tests. The study found no significant association between socio-demographic factors or yoga practice and physical readiness. In contrast, mental readiness was significantly associated with place of residence (p = 0.006), maternal education (p = 0.025), and participation in prenatal yoga (p = 0.000). Prenatal Yoga emerged as the strongest predictor of mental readiness for childbirth, highlighting its potential as a safe, accessible, and effective strategy to reduce anxiety, enhance self-efficacy, and improve emotional resilience. Promoting Prenatal Yoga within maternal health programs may empower women to face childbirth with greater confidence and mental preparedness.
Co-Authors Damanik, Brema JK Hidayanti, Maria Ulfa Nur Maria Estela Karolina Nidha, Amalia An Santoso, Ferry