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Inventarisasi Tanaman Berpotensi Sebagai Indikator Asam-Basa Alami Di Kota Kupang Mahmud, Nur R. Adawiyah; Ihwan, Ihwan; Jannah, Nur
bionature Vol 19, No 1 (2018): April
Publisher : Fakultas MIPA UNM

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (803.504 KB) | DOI: 10.35580/bionature.v19i1.7306

Abstract

Abstract.  This study investigated a natural acid-base indicator which is extracted from plants in Kupang city. There are 14 plants that potential as a source of natural indicator for acid base titration, i.e, Kol Ungu (Brassica oleracea Capitata Group), Turi Merah flower (Sesbania grandiflora L. Pers), Belimbing Wuluh flower (Averhoa bilimbi L), Kaktus Merah fruit (Opuntia vulgaris Mill), Ruelia flower (Ruellia simplex), Flamboyan flower (Delonix regia), bugenvil flower (Bougainvillea spectabilis Willd.), Bayam Merah leaves (Amaranthus tricolor L.) Jamblang fruit (Syzygium cumini L.), Murbey fruit (Morus alba L.), Pinang fruit (Areca catechu L.), Sirih fruit (Piper betle L.), Kunyit (Curcuma longa Linn), and Nanas Kerang leaves (Rhoeo discolor). Plants extract shows a sharp color change in acid and base solution. Promising results as a natural indicator also shown in acid base titration which is have similar equivalent point to synthetic indicator. We can use these natural indicators as an alternative to synthetic indicator because they are found to be simple, very useful, cheap, easy to extract, accurate, and eco-friendly. Keywords: Plant, Natural indicator, Acid-Base
Aktivitas Antimikroba Perasan Daun Kirinyuh (Chromolaena odorata L.) terhadap Candida albicans dan Pseudomonas aeruginosa Ernawati Ernawati; Nur Jannah
Jurnal Kedokteran dan Kesehatan Vol 17, No 2 (2021): JURNAL KEDOKTERAN DAN KESEHATAN
Publisher : Faculty of Public Health, Faculty of Medicine and Health, Universitas Muhammadiyah Jakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24853/jkk.17.2.137-144

Abstract

Daun kirinyuh (Chromolaena odorata) mengandung fenol, flavonoid, tannin, alkaloid dan saponin yang berpotensi sebagai senyawa antimikroba. Tujuan penelitian adalah untuk mengetahui aktivitas antimikroba daun kirinyuh terhadap Candida albicans dan Pseudomonas aeruginosa. Penelitian ini merupakan eksperimen laboratorium, pengujian antimikroba melalui metode difusi agar dengan kontrol positif (K+) menggunakan amoxilin untuk Pseudomonas aerugynosa dan ketokonazol untuk Candida albicans, aquades sebagai kontrol negatif (K-), dan perasan daun kirinyuh konsentrasi 100%, 80%, 60%, 40%, dan 20%. Bahan-bahan yang digunakan adalah isolat Candida albicans dan Pseudomonas aeruginosa, media MHA, aquades, amoxilin dan ketokonazol. Data diameter zona hambat yang dihasilkan setelah inkubasi 24 jam dianalisis secara deskriptif dengan mengklasifikasikan respon hambat sangat kuat (> 20-30 mm), kuat (10-20 mm), sedang (5-10 mm), lemah (< 5 mm). Hasil penelitian menunjukkan rata-rata zona hambat Candida albicans pada konsentrasi 20%, 40%, 60%, 80%, dan 100% adalah 10,3 mm, 11,03 mm, 11,66 mm, 12,83 mm, dan 13,82 mm, sedangkan untuk Pseudomonas aeruginosa 7,33 mm, 12,46 mm, 13,73 mm, 14,26 mm, dan 15,63 mm.  Hasil analisis data berdasarkan kategori respon hambat pertumbuhan termasuk kategori kuat dan sedang khusus pada konsentrasi 20% pada Pseudomonas aeruginosa.  Kesimpulan perasan daun kirinyuh memiliki aktivitas antimikroba terhadap pertumbuhan Candida albicans dan Pseudomonas aeruginosa..
The Immunomodulatory Effect of Elephantopus scaber and Sauropus androgynus Extract to Cellular Immune Response in Pregnant Mus muscullus Infected by Salmonella typhimurium Nur Jannah; Moch. Sasmito Djati; Sri Widyarti
The Journal of Experimental Life Science Vol. 6 No. 1 (2016)
Publisher : Postgraduate School, Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (944.87 KB) | DOI: 10.21776/ub.jels.2016.006.01.02

Abstract

Pregnancy has a high risk and is more susceptible to infectious diseases. E. scaber and S. androgynus contains saponins and flavonoids as an immunomodulatory that can increase the body's immunity. The purpose of this study is to determine the immunomodulatory effects of E. scaber and S. androgynus leaf extract against cellular immune response in pregnant mice infected S. typhimurium. This research used seven treatment groups including negative control (K-) mice without injected S. typhimurium, positive control (K+) mice were injected S. typhimurium and extract treatment with 5 variant doses and dissected on the 12th and 18th days. Lymphocytes was isolated from the blood, then relative number of CD4+ and CD8+ were analyzed with flow cytometry and data continued with ANOVA. Statistical analysis showed that different extract dose and duration of treatment had a significant effect on the number of CD4+ and CD8+ T cells. E. scaber and S. androgynus act as immunomudulatory effect and treatment with combination of extracts E. scaber and S. androgynus 50 mg.kg-1 BW + 112.5 mg.kg-1 BW respectively and treatment with extract of S. androgynus 150 mg.kg-1 BW are the optimum treatment which can restore immune system conditions such as normal pregnancy without infection.Keywords: Cellular Immune, E. scaber, Immunomodulatory, S. androgynus, S. typhimurium.