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p-Index From 2021 - 2026
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All Journal Indonesian Journal of Cardiology Indonesian Andrology and Biomedical Journal
Surya, Stevanus Christian
Unknown Affiliation
Health Professions Medicine & Pharmacology

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Collagen-Based Hydrogel Encapsulated Cardiosphere-Derived Cell (CDC): Potential of Stem Cells as Tissue Repair Therapy Post-Acute Myocardial Infarction Evananda, Maria Pramesthi Sabrina; Salim, Albert; Surya, Stevanus Christian; Suastika, Luh Olivia Saraswati
Jurnal Kardiologi Indonesia Vol 45 No 4 (2024): Online First - Indonesian Journal of Cardiology April-June 2021
Publisher : The Indonesian Heart Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30701/ijc.1281

Abstract

Acute myocardial infarction (AMI) is a global health issue that is the leading cause of morbidity and mortality. Post-AMI management currently has therapeutic and side effect limitations, and has not been able to repair damage to myocardial tissue caused by AMI. The development and discovery of therapeutic modalities with the potential for a more optimal therapeutic effect remains a challenge in this post-AMI treatment. The purpose of this literature review is to collect and analyze various sources related to collagen-based hydrogel encapsulated cardiosphere-derived cell (CDC). This literature review is written systematically by gathering library sources from various search engines, such as Google Scholar, PubMed, and Research Gate. According to the findings of the study, CDC has the potential to be used as a post-AMI therapy because it can promote regeneration of the heart, which has lost function as a result of the AMI. To achieve the greatest effect, this modality is administered intracoronary. This modality will be encapsulated with collagen hydrogel, which has a cardioprotective effect, in order to increase the survival and effectiveness of CDC. The use of collagen-based hydrogel encapsulated CDC can provide post-AMI cell regeneration effects comparable to existing modalities while having minimal side effects. Further investigation in larger and more definitive trials is needed to elucidate the potential use of CDC therapy in AMI.
The Relationship Between COVID-19 and Male Hypogonadism in Denpasar, Bali, Indonesia Limantoro, Joshua; Hane, Eugenius Kurniawan; Cahyani, Made Ratna Komala; Surya, Stevanus Christian; Oden, Gwyneth Felicia; Pramesemara, I Gusti Ngurah
Indonesian Andrology and Biomedical Journal Vol. 6 No. 2 (2025): December
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/iabj.v6i2.71477

Abstract

Background : Hypogonadism in men can be identified through various clinical and subjective symptoms, which may be assessed using the Aging Male Symptoms (AMS) questionnaire. COVID-19 infection has been suggested to impact hormonal and reproductive function in men, but the relationship between post-infection symptoms and hypogonadism risk based on subjective measures remains underexplored in Indonesia. Objective : This study aims to determine the association between COVID-19-related characteristics and the risk of hypogonadism in men, assessed using the AMS score. Methods : A cross-sectional study was conducted on 152 male residents of Denpasar, Bali, aged ≥18 years. Data were collected through online and offline questionnaires, including demographics, lifestyle, COVID-19 infection history, and AMS scores. Bivariate and multivariate analyses were used to identify associations between COVID-19 indicators and hypogonadism risk. Results : Among respondents, 32.24% had an AMS score ≥27, indicating potential hypogonadism. A higher proportion of AMS ≥27 was found in individuals with obesity, comorbidities, occasional smoking, and moderate alcohol consumption. Although more severe COVID-19 indicators (e.g., hospitalization, prolonged symptoms, oxygen use) were observed in the AMS ≥27 group, statistical analysis showed no significant association between SARS-CoV-2 infection and hypogonadism risk (p > 0.05). Conclusion : While men with a history of COVID-19 infection exhibited higher AMS scores suggestive of hypogonadism, no statistically significant relationship was found. Further longitudinal studies with hormonal assays are needed to explore the long-term impact of COVID-19 on male reproductive health.
Co-Authors Cahyani, Made Ratna Komala Evananda, Maria Pramesthi Sabrina Hane, Eugenius Kurniawan Limantoro, Joshua Oden, Gwyneth Felicia Pramesemara, I Gusti Ngurah Salim, Albert Suastika, Luh Olivia Saraswati