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All Journal TRILOGI: Jurnal Ilmu Teknologi, Kesehatan, dan Humaniora Indonesian Journal Health Science and Medicine
Makrufah, Makrufah
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Humanities Computer Science & IT Engineering Health Professions Medicine & Pharmacology Public Health Veterinary Other

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Toxicity of White Turi Leaf Extract on Liver Function in Mice: Toksisitas Ekstrak Daun Turi Putih pada Fungsi Hati Mencit Makrufah, Makrufah; Rohmah, Jamilatur
Indonesian Journal on Health Science and Medicine Vol. 2 No. 2 (2025): Oktober
Publisher : Universitas Muhammadiyah Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21070/ijhsm.v2i2.246

Abstract

General background: Sesbania grandiflora (L.) Pers., widely known as white turi, is traditionally used as analgesic, laxative, and other medicinal purposes. Specific background: Despite its therapeutic benefits, the plant contains secondary metabolites, including triterpenoids and alkaloids, with potential hepatotoxic properties, particularly pyrrolizidine alkaloids. Knowledge gap: Previous studies have indicated general toxicity of turi extracts but limited evidence exists on its subacute hepatic toxicity measured through enzymatic markers in animal models. Aim: This study investigated the toxicity of white turi leaf extract on liver function by assessing SGOT and SGPT levels in mice (Mus musculus). Results: Laboratory experiments using a posttest-only control group design were conducted with multiple dosage levels. Statistical analysis with Kruskal-Wallis revealed no significant differences in SGOT (p = 0.896) and SGPT (p = 0.527) levels between treatment and control groups, while ANOVA showed no significant change in liver weight (p = 0.089). Novelty: This research provides the first evidence that ethanolic white turi leaf extract, within the tested doses and 14-day observation, does not induce measurable hepatic dysfunction in mice. Implications: The findings suggest relative safety of white turi extract at tested doses, supporting its potential traditional use while highlighting the importance of further chronic toxicity studies. Highlights : White turi leaf extract showed no hepatotoxic effect in mice. SGOT-SGPT levels and liver weight remained within normal range. Supports safe traditional use but requires chronic toxicity evaluation. Keywords : Sesbania Grandiflora, White Turi Leaf, SGOT, SGPT, Hepatotoxicity
Peningkatan Kemampuan Membaca Al-Qur’an melalui Scientific Approach pada Pembelajaran Ilmu Tajwid di SD Insan Terpadu Sumberanyar Paiton Probolinggo Musolli, Musolli; Makrufah, Makrufah
TRILOGI: Jurnal Ilmu Teknologi, Kesehatan, dan Humaniora Vol 2, No 1 (2021): Sains dan Pendidikan Berbasis Teknologi Informasi
Publisher : Universitas Nurul Jadid

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (417.666 KB) | DOI: 10.33650/trilogi.v2i1.2819

Abstract

This study discusses learning tajwid in improving the ability to read the Qur'an through a scientific approach at SD Insan Terpadu Sumberanyar Paiton. Learning tajwid is part of the procedure for reading the Qur'an, so that in its journey many methods or approaches are found in learning. One approach that can be used to strengthen the learning of tajwid is scientific learning, namely a learning approach which consists of activities; observing, questioning, associating, experimenting, and networking. This study uses a qualitative case study type method. The results of his research show that the Scientific Approach approach in the learning process of Tajweed Science at SD Insan Terpadu is very effective so that it can improve students' reading of the Qur'an and is very enjoyable. In addition, students are also able to master the material of recitation, gharib, and hadiths that they have learned.
Co-Authors Jamilatur Rohmah Musolli, Musolli