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Khairani , Tetty Noverita
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Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Nursing Public Health

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Kombinasi Formulasi Simplisia Serbuk Daun Seroja (Nelumbo nucifera Gaertn.) Dengan Serbuk Rimpang Jahe (Zingiber officinale) Dalam Sediaan Teh Celup Sebagai Minuman Kesehatan Fitri , Khairani; Khairani , Tetty Noverita; Tarigan , Rida Evalina; Ananda , Sheila Rizka; Arista , Eni
Journal of Pharmaceutical and Sciences JPS Volume 8 Nomor 3 (2025)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v8i3.1078

Abstract

Introduction: Indonesia is a tropical country with high humidity that supports the growth of various plants, including medicinal herbs such as lotus leaves and ginger. Objective: This study aims to formulate a combination of powdered lotus leaves (Nelumbo nucifera Gaertn.) and powdered ginger rhizome (Zingiber officinale) into tea bag preparations and to evaluate their quality. Methods: The study employed an experimental method. Testing was conducted based on the Indonesian National Standard (SNI) parameters for tea bags, including organoleptic evaluation, moisture content test, total ash content test, acid-insoluble ash test, water-soluble extractive test, and hedonic test. Results: The concentrations of lotus leaf powder and ginger powder formulated were 100:0 (F0), 90:10 (F1), 80:20 (F2), 70:30 (F3), 60:40 (F4), and 50:50 (F5). The hedonic test results indicated that formula F5 (50:50) was the most preferred by the panelists compared to other formulas, with the highest average score. However, overall, the commercial tea (positive control) still obtained a higher preference score. Conclusion: The combination of lotus leaf powder and ginger rhizome powder was successfully formulated into tea bag preparations. Formula F5 (50:50) was selected as the best among all tested formulations, although its preference level remained lower than that of commercial tea.
Analisis Escherichia coli dan Zat Kimia pada Minuman Es Jagung Khairani , Tetty Noverita; Fitri , Khairani; Tarigan, Rida Evalina; Khairani, Cut; Natasya, Alfa
Journal of Pharmaceutical and Sciences JPS Volume 8 Nomor 3 (2025)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v8i3.1079

Abstract

The addition of inappropriate food additives (BTM) such as artificial sweeteners, and synthetic dyes which are added intentionally by food vendors is one of the problems that cause food not suitable for consumption because it can cause health problems. The purpose of this study was to analyze the dyes, sweeteners and E.coli in corn ice drinks sold in Pakam. The study design uses qualitative laboratory analysis. The population in this study is the corn ice traders in the city of Lubuk Pakam, amounting to 5 traders. The sample consisted of 5 traders who were in the Regent's Office, Galang Street, Segangular Field, Labu Beach and Ahmad Dahlan Street. The work procedure is by checking the coloring agent, sweetener and Escerichia coli examination. The results of laboratory tests revealed that the coloring agents in samples A and E contained Tartrazine and in samples B, C and D contained Tartrazine and Sunset Yellow, sweeteners were found in samples C and E and in samples A, B and D were not found to contain artificial sweeteners and 5 samples (100%) showed a total value of escerichia coli <3 APM / ml per ml sample. The conclusion in this study is that corn ice drinks sold in the city of Lubuk Pakam use coloring agents and sweetening agents that are permitted based on the Republic of Indonesia Ministerial Regulation No. 033 of 2012 and containing Escerichia coli of <3 APM / ml are still within the allowed limits in accordance with the Indonesian National Standard (SNI) and the Head of Indonesian National Drug and Food Control Agency Regulation No. HK.00.06.1.52.4011.
Pengaruh Ekstrak Daun Nanas Terhadap Pertumbuhann Candida albicans Dan Malassezia furfur Dalam Bentuk Sediaan Shampo Herbal Abadi , Hafizhatul; Khairani , Tetty Noverita; Fitri, Khairani; Diana, Vivi Eulis; Leny, Leny; Hasibuan, Amalia Juliani
Journal of Pharmaceutical and Sciences JPS Volume 8 Nomor 4 (2025)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v8i4.1181

Abstract

Background: Dandruff is a common scalp problem often caused by the overgrowth of fungi such as Candida albicans and Malassezia furfur. Pineapple leaves (Ananas comosus (L.) Merr.) are known to contain active antifungal compounds, such as alkaloids, flavonoids, saponins, and tannins, making them a potential active ingredient for anti-dandruff preparations. Objective: This study aimed to formulate an herbal anti-dandruff shampoo using pineapple leaf ethanol extract and to evaluate its effectiveness in inhibiting the growth of Candida albicans and Malassezia furfur. Methods: This experimental research used the disc diffusion method with PDA and SDA media to test antifungal inhibition. The shampoo preparations were formulated with varying extract concentrations (10%, 20%, 30%). The evaluation of the preparations included organoleptic tests, homogeneity, pH, foam height, viscosity, stability (cycling test), skin irritation, and hedonic tests. Results: The resulting shampoo preparation had a blackish-brown color, liquid form, and a menthol odor. Evaluation results showed the preparation was homogeneous, with pH values (5.0-5.8), foam height, and viscosity meeting the requirements. The preparation was also stable during the cycling test and did not cause irritation. The antifungal activity test showed that increasing the extract concentration increased the inhibitory power. The formula with a 30% concentration (F3) provided the greatest inhibition against Candida albicans (average 15.76 mm) and Malassezia furfur (average 15.9 mm), which is categorized as strong. Conclusion: Pineapple leaf ethanol extract was successfully formulated into an effective herbal anti-dandruff shampoo preparation, with the 30% concentration being the most optimal. It is recommended that further research investigate the antifungal activity of this extract against other types of fungi and in different dosage forms.
Co-Authors Abadi , Hafizhatul Ananda , Sheila Rizka Arista , Eni Diana, Vivi Eulis Fitri , Khairani Fitri, Khairani Hasibuan, Amalia Juliani Khairani, Cut Leny Leny, Leny Natasya, Alfa Rida Evalina Tarigan Tarigan , Rida Evalina