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All Journal Jurnal Pertahanan : Media Informasi tentang Kajian dan Strategi Pertahanan yang Mengedepankan Identity, Nasionalism dan Integrity West Science Nature and Technology
Sakina, Zafira Naja
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Metagenomic and Functional Profiling of Endophytes from Indonesian Medicinal Plants: Potentials for Sustainable Bioprospecting Sakina, Zafira Naja; Imam Supriyadi; Budi Santoso
West Science Nature and Technology Vol. 3 No. 03 (2025): West Science Nature and Technology
Publisher : Westscience Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58812/wsnt.v3i03.2011

Abstract

Indonesia's extraodinary plant biodiversity remains underutilised in microbial bioprospecting, despite its vast potential to support sustainable biotechnological innovation. This study aims to explore and characterise endophytic microorganisms associated with selected Indonesian medicinal plants, focusing on their genetic and functional traits relevant to bioactive compound production. Addressing a gap in integrative profiling, the study adopts a qualitative literature-based methodology, synthesising findings from over 30 peer-reviewed, Scopus-indexed studies published between 2015 and 2024. These studies involve next-generation sequencing, biosynthetic gene cluster (BGC) analysis, and in vitro functional assays. Notably, endophytes isolated from plants such as Curcuma longa, Andrographis paniculata, and Phyllanthus niruri harbour diverse and unique BGCs, including non-ribosomal peptide synthetases (NRPS) and polyketide synthases (PKS), which are linked to antimicrobial, enzymatic, and plant growth-promoting activities. The originality of this study lies in its interdisciplinary synthesis bridging microbial ecology, genomics, and biotechnology, contributing to the theoretical advancement of microbial symbiosis and offering practical implications for natural product development, sustainable agriculture, and Indonesia's emerging bioeconomy
Co-Hydrothermal Carbonization: An Innovative Solution for Enhancing National Energy Resilience Through the Production of Clean Solid Fuels from Sewage Sludge and Coal Slime Ardyanto, Fakhriyan; Sakina, Zafira Naja; Thamrin, Suyono; Laksmono, Rudy
Jurnal Pertahanan: Media Informasi tentang Kajian dan Strategi Pertahanan yang Mengedepankan Identity, Nasionalism dan Integrity Vol 12, No 1 (2026)
Publisher : The Republic of Indonesia Defense University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33172/jp.v12i1.20031

Abstract

Waste management, particularly the handling of sewage sludge generated from water treatment and coal slime as a byproduct of mining activities, poses a serious environmental challenge. Co-Hydrothermal Carbonization (co-HTC) technology has emerged as an innovative solution to convert these two types of waste into clean and efficient solid fuel. This study aims to explore the characteristics of the co-HTC process, the environmental benefits it offers, the implementation challenges it faces, and its potential applications in supporting a sustainable energy transition. The research employs a literature review approach, gathering information from scholarly articles, research reports, and policy documents related to co-HTC. The selection of literature is based on topic relevance, publication year, and the quality of research methodology. A critical analysis identifies the main characteristics of co-HTC technology, its environmental benefits, implementation challenges, and application opportunities. The findings indicate that co-HTC can significantly reduce waste volume and produce hydrochar as an alternative fuel with high calorific value and low carbon emissions. Additionally, hydrochar has potential as an organic fertilizer that supports sustainable agriculture. However, challenges such as the cost of oxygen production and the need for infrastructure investment remain significant hurdles.
Co-Authors Ardyanto, Fakhriyan Budi Santoso Imam Supriyadi Laksmono, Rudy Thamrin, Suyono