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All Journal Jurnal Buana Farma International Journal of Social Science, Educational, Economics, Agriculture Research, and Technology (IJSET)
Ma’rifah
Unknown Affiliation
Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemistry Computer Science & IT Economics, Econometrics & Finance Education Immunology & microbiology Medicine & Pharmacology

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SYSTEMATIC LITERATURE REVIEW: KANDUNGAN SENYAWA BIOAKTIF DAN AKTIVITAS SITOTOKSIK EKSTRAK ALANG-ALANG TERHADAP SEL KANKER Nuh, Muhammad; Ma’rifah; Haq, Nasrul; Akrom
Jurnal Buana Farma Vol. 5 No. 3 (2025): Jurnal Buana Farma : Jurnal Ilmiah Farmasi
Publisher : Fakultas Farmasi Universitas Buana Perjuangan Karawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36805/jbf.v5i3.1452

Abstract

Imperata cylindrica (Imperata cylindrica) is a traditional medicinal plant long used in various countries and is known to contain various bioactive compounds with anticancer potential. Research on the cytotoxic activity of Imperata cylindrica continues to develop, but results are still varied, requiring a systematic review to summarize the available scientific evidence. This study aims to review the bioactive compound content and cytotoxic activity of Imperata cylindrica extract against various cancer cells. A systematic literature review method was conducted by searching articles from international and national databases using relevant inclusion and exclusion criteria. Of the total 410 articles found, 10 articles were selected to meet the requirements for analysis. The results of the study showed that cogongrass extract with various solvents (ethanol, methanol, water, n-hexane fraction, ethyl acetate fraction, and chloroform) has cytotoxic activity against various cancer cell lines, such as breast (MCF-7), cervical (HeLa), colon (HT-29), lung (A549), liver (HepG2), prostate (PC-3), and leukemia (HL-60). The identified cytotoxic mechanisms include induction of apoptosis, cell cycle arrest, inhibition of migration, antioxidant, anti-inflammatory, and immunomodulatory activities. The dominant compounds that play a role include flavonoids, alkaloids, terpenoids, saponins, and tannins. In conclusion, cogongrass extract has great potential as a candidate for natural anticancer agents, although further research in the form of in vivo tests and clinical trials is still very necessary to ensure its effectiveness and safety.
THE SYNERGY OF HUMAN AND AI CREATIVITY: AN EXPERIMENT IN CO-CREATING EFFECTIVE MARKETING CONTENT Ma’rifah; Lukmanul Hakim; Tibrani
International Journal of Social Science, Educational, Economics, Agriculture Research and Technology (IJSET) Vol. 5 No. 5 (2026): APRIL
Publisher : RADJA PUBLIKA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.5281/zenodo.19641415

Abstract

This study explores the synergy between human and artificial intelligence (AI) creativity in the co-creation of effective marketing content. As generative AI tools become increasingly integrated into marketing practices, understanding how human and AI capabilities interact has become essential. Using an experimental approach, this research compares human-created, AI-generated, and co-created content across key dimensions, including creativity, authenticity, engagement, and overall effectiveness. The findings reveal that while human-created content excels in emotional depth and authenticity, and AI-generated content demonstrates strengths in efficiency and scalability, co-created content consistently achieves the most balanced and effective outcomes. Perceived creativity and authenticity emerge as critical mediating factors that influence consumer responses, shaping trust, engagement, and persuasive impact. The study also highlights the role of moderating factors such as consumer familiarity with AI and task complexity in determining the effectiveness of different content creation modes. A conceptual framework is proposed to explain the relationships between content creation mode, perceptual mediators, and marketing outcomes. This research contributes to the literature on hybrid creativity and provides practical insights for marketers seeking to optimize content strategies through human–AI collaboration.
Co-Authors Akrom, Akrom haq, Nasrul Lukmanul Hakim Muhammad Nuh Tibrani