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All Journal Majalah Obat Tradisional As-syifaa Jurnal Farmasi Journal of Economics Research and Social Sciences Jurnal Buana Farma
haq, Nasrul
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Biochemistry, Genetics & Molecular Biology Chemistry Economics, Econometrics & Finance Health Professions Immunology & microbiology Medicine & Pharmacology Public Health

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Analisis Pengaruh Investasi, Angkatan Kerja dan Pendidikan Terhadap Pertumbuhan Ekonomi di Pulau Kalimantan Haq, Nasrul; Yuliadi, Imamudin
Journal of Economics Research and Social Sciences Vol 2, No 2 (2018)
Publisher : Program Studi Ekonomi FEB UMY

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18196/jerss.v2i2.9876

Abstract

Pada era ekonomi saat ini, peran ekonomi tidak hanya dimainkan oleh pemerintah pusat atau negara saja. Lebih dari itu setiap daerah memiliki peran penting dalam andil memajukan perekonomian negara. Pemerintah daerah dianggap lebih memahami kondisi ekonomi di lapangan, sehingga kebijakan yang dibuat sudah seharusnya berdasarkan kebutuhan pembangunan ekonomi daerah. Maka dari itu, penelitian ini bertujuan untuk menganalisis pengaruh investasi, angkatan kerja dan pendidikan terhadap pertumbuhan ekonomi daerah, tepatnya di pulau Kalimantan. Penelitian ini merupakan penelitian empiris dengan pendekatan kuantitatif. Data yang digunakan dalam penelitian ini berupa data sekunder dari 4 Provinsi di pulau Kalimantan pada tahun 2008-2016. Model analisis yang digunakan adalah analisis regresi data panel dengan fixed effect model. Hasil penelitian ini menunjukan bahwa variabel investasi berpengaruh positif dan signifikan terhadap pertumbuhan ekonomi, variabel angkatan kerja berpengaruh positif dan signifikan terhadap pertumbuhan ekonomi dan variabel pendidikan berpengaruh positif dan signifikan terhadap pertumbuhan ekonomi.
SYSTEMATIC LITERATURE REVIEW: KANDUNGAN SENYAWA BIOAKTIF DAN AKTIVITAS SITOTOKSIK EKSTRAK ALANG-ALANG TERHADAP SEL KANKER Nuh, Muhammad; Ma’rifah; Haq, Nasrul; Akrom
Jurnal Buana Farma Vol. 5 No. 3 (2025): Jurnal Buana Farma : Jurnal Ilmiah Farmasi
Publisher : Fakultas Farmasi Universitas Buana Perjuangan Karawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36805/jbf.v5i3.1452

Abstract

Imperata cylindrica (Imperata cylindrica) is a traditional medicinal plant long used in various countries and is known to contain various bioactive compounds with anticancer potential. Research on the cytotoxic activity of Imperata cylindrica continues to develop, but results are still varied, requiring a systematic review to summarize the available scientific evidence. This study aims to review the bioactive compound content and cytotoxic activity of Imperata cylindrica extract against various cancer cells. A systematic literature review method was conducted by searching articles from international and national databases using relevant inclusion and exclusion criteria. Of the total 410 articles found, 10 articles were selected to meet the requirements for analysis. The results of the study showed that cogongrass extract with various solvents (ethanol, methanol, water, n-hexane fraction, ethyl acetate fraction, and chloroform) has cytotoxic activity against various cancer cell lines, such as breast (MCF-7), cervical (HeLa), colon (HT-29), lung (A549), liver (HepG2), prostate (PC-3), and leukemia (HL-60). The identified cytotoxic mechanisms include induction of apoptosis, cell cycle arrest, inhibition of migration, antioxidant, anti-inflammatory, and immunomodulatory activities. The dominant compounds that play a role include flavonoids, alkaloids, terpenoids, saponins, and tannins. In conclusion, cogongrass extract has great potential as a candidate for natural anticancer agents, although further research in the form of in vivo tests and clinical trials is still very necessary to ensure its effectiveness and safety.
PENENTUAN NILAI SPF DARI EKSTRAK ETANOL DAUN KELOR (Moringa oleifera Lam) DAN DAUN KEMANGI (Ocimum basilicum L.) Mirawati, Mirawati; Purnamasari M, Vina; Harliman, Isrhopana Kinana; Sahira, Sahira; Bade, Iskandar Zulkarnain Mahmud; Hasrawati, A.; Haq, Nasrul
As-Syifaa Jurnal Farmasi Vol 17, No 1 (2025): AS-SYIFAA JURNAL FARMASI
Publisher : Fakultas Farmasi UMI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56711/jifa.v17i1.1144

Abstract

Excessive exposure to ultraviolet (UV) radiation can lead to various skin issues, ranging from premature aging to an increased risk of skin cancer. As a result, the exploration of natural ingredients for UV protection has gained growing attention in cosmetic research. This study aims to evaluate the UV-absorbing potential of ethanolic extracts from Moringa oleifera Lam leaves and Ocimum basilicum L. leaves by determining their Sun Protection Factor (SPF) values. Using spectrophotometric analysis across different concentrations, both extracts demonstrated significant potential as natural sunscreen agents. At a concentration of 1500 ppm, the highest SPF values were recorded at 45.683 for Moringa oleifera Lam and 47.037 for Ocimum basilicum L. These findings highlight the promising potential of both plant extracts as active ingredients in sun-protective skincare formulations
Molecular Analysis and Activities of Bioactive Compounds from Symbiont Bacteria Isolates Polycarpa aurata Herwin, Herwin; Alam, Gemini; Sartini, Sartini; Rahim, Abdul; Nurung, Ayyub Harly; Amirullah, Amirullah; Haq, Nasrul
Majalah Obat Tradisional Vol 31, No 1 (2026)
Publisher : Faculty of Pharmacy, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/mot.105930

Abstract

Symbiont bacteria associated with Polycarpa aurata are known to produce secondary metabolites with diverse bioactive properties, including antibacterial, anticancer, antifungal, and antiprotozoal activities. This study evaluated the antibacterial and antibiofilm activities of symbiotic bacterial isolates obtained from the white morphotype of P. aurata collected from Barrang Lompo Island, Makassar City, Indonesia. The agar diffusion method and ELISA reader assay were employed for antibacterial and antibiofilm analyses, respectively. Four pure isolates were obtained and designated AQ2-1, AL2-3, AL2-4, and AL2-5. Molecular identification based on 16S rRNA gene sequencing indicated that isolate AQ2-1 corresponded to Pseudomonas aeruginosa strain AB18. This isolate exhibited a pronounced inhibition zone against Bacillus subtilis, with an optimal incubation period of 68 h for secondary metabolite production. Chemical analysis of the bioactive compounds from isolate AQ2-1 identified adenine riboside and bis(2-ethylhexyl) benzene-1,2-dicarboxylate as the major constituents. Adenine riboside exhibited the highest antibacterial activity, producing an inhibition zone of 12.2 mm against Escherichia coli ATCC 25922, while bis(2-ethylhexyl) benzene-1,2-dicarboxylate produced an inhibition zone of 10.8 mm against Staphylococcus epidermidis ATCC 14990. In the antibiofilm assay, adenine riboside achieved the highest inhibition at 77.09% against Staphylococcus aureus ATCC 25923, whereas bis(2-ethylhexyl) benzene-1,2-dicarboxylate inhibited Streptococcus mutans ATCC 25175 by 73.61%. These findings demonstrate that secondary metabolites produced by the AQ2-1 isolate of symbiont bacteria from P. aurata possess strong antibacterial and antibiofilm activities and may serve as promising candidates for future antimicrobial development.
Co-Authors A Hasrawati Abdul Rahim Akrom, Akrom Amirullah -, Amirullah Bade, Iskandar Zulkarnain Mahmud Gemini Alam Harliman, Isrhopana Kinana Herwin Herwin, Herwin Imamudin Yuliadi, Imamudin Ma’rifah Mirawati Mirawati Muhammad Nuh Nurung, Ayyub Harly Sahira, Sahira Sartini Sartini Vina Purnamasari M, Vina