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Aisyah, -
Fakultas MIPA dan Kesehatan Universitas Muhammadiyah Riau
Agriculture, Biological Sciences & Forestry Chemistry Nursing Physics

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SINTESIS DAN UJI AKTIVITAS ANTIOKSIDAN SENYAWA 3-(4-METOKSIFENIL)-5-NAFTALEN-1-IL-1-FENIL-4,5-DIHIDRO-PIRAZOL Aisyah, -; Jasril, -; Teruna, Hilwan Yuda
Sistem Informasi Vol 8 No 01 (2017): Jurnal Photon
Publisher : Fakultas MIPA dan Kesehatan Universitas Muhammadiyah Riau

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Abstract

A pyrazoline analog, 3-(4-methoxy-phenyl)-5-naphtalen-1-yl-1-phenyl-4,5-dihydro-pyrazole (PF CA-4OMe) has been synthesized via intermolecular cyclization between substituted chalcones and phenylhydrazine using glacial acetic acid as a catalyst under microwave irradiation. The structure of the compound was characterized based on the interpretation of UV, FTIR, HRMS, 1H-NMR, 13C-NMR, HSQC and HMBC spectra. The antioxidant test was carried out by 2,2-diphenyl-1-picrylhydrazyl (DPPH) method. The result show that PF CA-4OMe was proved to have antioxidant activity with IC50 387,64 µg/mL.
Co-Authors Hilwan Yuda Teruna Jasril Jasril