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Hurulhanifa, Fatmanur
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Health Professions

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Diagnosis Sarkopenia pada Geriatri Menggunakan Akselerometer Actigraph wGT3XBT: Tinjauan Naratif: Analisis Hurulhanifa, Fatmanur; Laranti, Nimas Adiani Sekar; Shabrina, Hanifa Nur; Agatri, Norina; Mahardhika, Gembong Satria
Cermin Dunia Kedokteran Vol 52 No 10 (2025): Oktober 2025
Publisher : PT Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55175/cdk.v52i10.1421

Abstract

Sarcopenia is a degenerative condition of age-related decline in muscle mass and strength. The worldwide occurrence of sarcopenia varied from 8% to 36% in those under the age of 60, and from 10% to 27% in those aged 60 and above. There is 9.92% or around 26.82 million, elderly people in Indonesia. Several studies have stated that in 2020, the incidence of sarcopenia in Indonesia ranged from 9.1% to 59%. Various studies have shown that accelerometers can provide a quantitative measurement of physical activity, positively correlated with muscle mass and strength in the elderly. Accelerometers, particularly the Actigraph wGT3X-BT, offer an objective approach to measuring physical activity and provide important insights into sarcopenia. Accelerometers offer an unbiased method for quantifying physical activity, offering valuable information on sarcopenia, and serving as a clinical diagnostic tool for this disorder characterized by reduced muscle mass and function. Literature review suggests that the Actigraph wGT3X-BT accelerometer has great potential for early detection and diagnosis of sarcopenia. The integrated use of this technology is expected to improve the accuracy of diagnosis and enable more effective interventions, thereby improving the quality of life of the elderly in Indonesia.
Antimicrobial Resistance in Chronic Diarrhea: A Case Report of Cefazolin-Resistant Enteric Infection: Case Report Mahardhika, Gembong Satria; Izzati, Aulia Nurul; Laranti, Nimas Adiani Sekar; Hurulhanifa, Fatmanur; Shabrina, Hanifa Nur; Santosa, Qodri
Cermin Dunia Kedokteran Vol 53 No 10 (2026): Oktober 2026 - CDK 357
Publisher : PT Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55175/cdk.v53i10.1944

Abstract

Introduction: Antimicrobial resistance is an emerging global health challenge that may lead to treatment failure and prolonged illness. Although cefazolin resistance is relatively uncommon, it can complicate infectious disease management, including chronic diarrhea. Case: A 7-month-old girl presented with fever and chronic mucoid diarrhea. Despite treatment with multiple antibiotics, including cefazolin, metronidazole, and vancomycin, her symptoms worsened, with diarrhea increasing to seven episodes daily, accompanied by severe anemia and malnutrition. Antibiotic susceptibility testing revealed isolated cefazolin resistance (MIC = 64 μg/mL). After susceptibility-guided treatment with intravenous ciprofloxacin and supportive care, the patient improved significantly and was discharged after 10 days. Discussion: This case highlights the importance of considering antimicrobial resistance in children with persistent diarrhea who fail to respond to empirical antibiotic therapy. Cefazolin resistance likely contributed to treatment failure and clinical deterioration. Early microbiological investigation and susceptibility-guided therapy were essential to achieve clinical recovery and prevent further complications. Conclusion: Clinicians should consider cefazolin-resistant enteric infection in cases of chronic diarrhea with poor response to empirical treatment. Prompt culture and antibiotic susceptibility testing are crucial to guide appropriate antimicrobial therapy and improve patient outcomes.
Co-Authors Agatri, Norina Izzati, Aulia Nurul Laranti, Nimas Adiani Sekar Mahardhika, Gembong Satria Qodri Santosa, Qodri Shabrina, Hanifa Nur