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Febriyanti, audy zahra
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Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Education Immunology & microbiology Public Health

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Aktivitas Antibakteri Dan Antijamur Ekstrak Etanol Daun Jamblang (Syzygium cumini L.) Terhadap Bakteri Propionibacterium acnes, Pseudomonas aeruginosa Dan Jamur Candida albicans ULFAH, MARIAM -; irawan, ade -; Febriyanti, audy zahra
BEST Journal (Biology Education, Sains and Technology) Vol 8, No 2 (2025): September 2025
Publisher : Program Studi Pendidikan Biologi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30743/best.v8i2.11971

Abstract

This research is motivated by the researcher's observation of the many cases of skin diseases in Indonesia, one of which is skin infections caused by bacteria and fungi that can be treated with natural ingredients such as jamblang leaves (S. cumini L.). This study aims to identify secondary metabolite compounds and prove the ability of ethanol extract of jamblang leaves (S. cumini L.) to inhibit the growth of Propionibacterium acnes, Pseudomonas aeruginosa, and Candida albicans. The extract was made by maceration using 96% ethanol for 3x24 hours. Then, phytochemical screening, TLC analysis and testing of antibacterial and antifungal activity were carried out with concentration variations of 20%, 40%, and 60% using the disc diffusion method. Based on the results of the study, it can be concluded that the ethanol extract of jamblang leaves contains secondary metabolites such as alkaloids, tannins, saponins, and flavonoids that play a role in inhibiting the growth of bacteria and fungi. Antibacterial and antifungal activity showed that the 60% concentration had the largest inhibition zone, namely P. acnes bacteria of 14.38 mm, P. aeruginosa of 12.61 mm, and C. albicans fungus of 11.23 mm, so that all results were categorized as "strong".
Aktivitas Antibakteri Dan Antijamur Ekstrak Etanol Daun Jamblang (Syzygium cumini L.) Terhadap Bakteri Propionibacterium acnes, Pseudomonas aeruginosa Dan Jamur Candida albicans Ulfah, Mariam; Irawan, Ade; Febriyanti, Audy Zahra
BEST Journal (Biology Education, Sains and Technology) Vol 8, No 2 (2025): September 2025
Publisher : Program Studi Pendidikan Biologi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30743/best.v8i2.13516

Abstract

Penelitian ini dilatarbelakangi oleh pengamatan peneliti terhadap banyaknya kasus penyakit kulit di Indonesia, salah satunya adalah infeksi kulit yang disebabkan oleh bakteri dan jamur yang dapat diobati dengan bahan alami seperti daun jamblang (S. cumini L.). Penelitian ini bertujuan untuk mengidentifikasi senyawa metabolit sekunder dan membuktikan kemampuan ekstrak etanol daun jamblang (S. cumini L.) dalam menghambat pertumbuhan Propionibacterium acnes, Pseudomonas aeruginosa, dan Candida albicans. Ekstrak dibuat dengan cara maserasi menggunakan etanol 96% selama 3x24 jam. Kemudian dilakukan skrining fitokimia, analisis KLT dan pengujian aktivitas antibakteri dan antijamur dengan variasi konsentrasi 20%, 40%, dan 60% menggunakan metode difusi cakram. Berdasarkan hasil penelitian, dapat disimpulkan bahwa ekstrak etanol daun jamblang mengandung metabolit sekunder seperti alkaloid, tanin, saponin, dan flavonoid yang berperan dalam menghambat pertumbuhan bakteri dan jamur. Aktivitas antibakteri dan antijamur menunjukkan bahwa konsentrasi 60% memiliki zona hambat terbesar, yaitu bakteri P. acnes sebesar 14,38 mm, P. aeruginosa sebesar 12,61 mm, dan jamur C. albicans sebesar 11,23 mm, sehingga semua hasil dikategorikan "kuat
Co-Authors Ade Irawan irawan, ade - Ulfah, Mariam ULFAH, MARIAM -