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All Journal Journal of Medical Genetics and Clinical Biology (JMGCB) Magenta Journal De Healthymedi
Mohammed, Nebras Rada
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Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Nursing Public Health Veterinary

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ELIMINATION OF BIOFILM PRODUCED BY ESCHERICHIA COLI AFTER EXPOSURE TO STRONTIUM SR90 AND CESIUM CS137 RADIOACTIVE SOURCE IN DIFFERENT DOSES Mohammed, Nebras Rada
Journal of Medical Genetics and Clinical Biology Vol. 1 No. 8 (2024): Journal of Medical Genetics and Clinical Biology
Publisher : PT. Antis International Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61796/jmgcb.v1i8.831

Abstract

Objective:. The purpose of this research in order to remove biofilm produced from E. coli with different radioactive sources.Study design: Case–control in analytical and cross-sectional in descriptive study design. Backgrounds: The bacterium E. coli which is pathogenic to the urinary tract, depends on a wide number of virulence determinants, as it is the most important bacterium responsible for urinary tract infections. Radiation is power in the appearance of undulations or spout of mote. There are several types of radiance overall concerning us. Alpha dissolution occurs while the mote throw of the nucleus that constitute of two no and two P+. Beta dissolution a no is convert a P+ and an e- is released of the nucleus. Gamma dissolution happen through residuum power in the nucleus next alpha or beta dissolution or subsequent no catch (a kind of atomic response) in a nuclear reactor. Methodology: Study populations and bacterial isolates with diagnosing E. coli from catheter and several diseases from patients in Baghdad hospitals in 2023/ 2024. Expose the bacteria to radiance released of Sr90 and CS137 radioactive sources in various doses with screening biofilm production before and after exposure to radiation. Results: The results show that there is a high killing rate of E. coli during exposure to Cesium-90 and Cesium-137 radioactive sources. As well as loss of biofilm production at different doses. Conclusion: Firstly, the impact of radiance of various radioactive sources occasion the homicide of E. coli. Secondly, the impact of radiance released of radioactive sources in various doses is analogous in homicide of E. coli.
The Therapeutic Strategies for Eliminating Biofilm Produced by Staphylococcus Aureus Isolated from Catheter by Exposing to Radiation Emitted from Radioactive Sources (In Vitro) Mohammed, Nebras Rada; Ali, Noor
Magenta Journal De Healthymedi Vol. 1 No. 2 (2024): Magenta Journal De Healthymedi
Publisher : Generasi Sains Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37899/mjdh.v1i2.45

Abstract

This study aimed to evaluate the effectiveness of Sr90 radiation in eliminating biofilm production and inhibiting the growth of Staphylococcus aureus, a Gram-positive, facultative anaerobic bacterium responsible for infections such as pneumonia, sepsis, and bacteremia, whose virulence is enhanced by biofilm formation. A cross-sectional descriptive design combined with a case–control analytical approach was employed, with bacterial isolates obtained from catheters and other clinical samples of patients in Baghdad hospitals during 2023–2024. Biofilm-producing S. aureus isolates were exposed to varying doses of Sr90 radiation, with and without aluminum shielding, and their biofilm activity was assessed using Congo-Red Agar before and after exposure. Results demonstrated that all isolates (100%) exhibited biofilm production prior to treatment; however, after exposure to Sr90, biofilm production was completely inhibited (0%), as indicated by red colony coloration on Congo-Red Agar. Furthermore, Sr90 exposure produced 100% bactericidal activity across increasing doses and time intervals, whether aluminum shielding was applied or not. These findings provide evidence that Sr90 radiation effectively disrupts biofilm production and eradicates S. aureus, highlighting its potential as an innovative therapeutic strategy for managing biofilm-associated infections.
Co-Authors Ali, Noor