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All Journal Journal of Medical Genetics and Clinical Biology (JMGCB)
Bazzaz, Ayoub A.
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Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Nursing

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ALTERATIONS IN HEMATOLOGICAL INDICES IN ANTENATAL AND POSTNATAL MOTHERS WITHIN KERKUK PROVINCE, IRAQ Azeez, Sarah T.; Bayatli, Feedan J.; Bazzaz, Ayoub A.; Chelebi, Noorhan A.
Journal of Medical Genetics and Clinical Biology Vol. 1 No. 11 (2024): Journal of Medical Genetics and Clinical Biology
Publisher : PT. Antis International Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61796/jmgcb.v1i11.1019

Abstract

Objective: The purpose of this study is to examine changes in hemoglobin, packed cell volume, white blood cells, and platelet counts in Iraqi women from Kirkuk Province during the prenatal and postnatal phases. Methods: During the course of a year, 600 women attended Azadi Hospital in Kirkuk, including 300 pregnant women in the third trimester and 300 postpartum women. An automated analyzer was used to collect and analyze blood samples, and the outcomes were contrasted with those of a control group of 60 university students who were not pregnant. Results Hematological parameters showed notable alterations. During pregnancy, hemoglobin and packed cell volume dropped, but after delivery, they rose (p < 0.022). During pregnancy, the white blood cell count was significantly greater (p < 0.001), and it continued to rise after delivery. There was no discernible change in the platelet count. Instead of clinical situations, these deviations were ascribed to normal physiological processes. Novelty: This study contributes to better health monitoring and risk assessment for maternal care by shedding light on the typical hematological alterations that occur in Iraqi women throughout pregnancy and the postpartum phase.
ACCELERATION HEALING AND OSSEO-INTEGRATION PROCESSES OF CPTI IMPLANT BY COATING TEETH WITH COLLAGEN-POLYCAPROLACTONE FIBER SCAFFOLD Al-Bayati, Shanai; Jassim, Raghdaa; Jabur, Akram; Bazzaz, Ayoub A.
Journal of Medical Genetics and Clinical Biology Vol. 1 No. 12 (2024): Journal of Medical Genetics and Clinical Biology
Publisher : PT. Antis International Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61796/jmgcb.v1i12.1067

Abstract

Objective: This study aimed to enhance osseointegration and healing by combining electrospinning techniques with collagen and polycaprolactone (PCL) as a coating for commercial pure titanium (CpTi) implants. Methods: In vitro experiments utilized glacial acetic acid as a solvent system to create collagen/PCL coatings with varying PCL concentrations (10%, 15%, 20% w/v). Morphological and physical characterizations were conducted using scanning electron microscopy (SEM), atomic force microscopy (AFM), and wettability tests. In vivo studies involved implanting collagen/PCL-coated CpTi cylinders into the femoral bone of New Zealand rabbits, followed by histological analysis at 2 and 6 weeks. Results: SEM revealed that scaffolds with higher PCL concentrations exhibited finer nanofiber structures (average diameter: 232 nm) and enhanced hydrophilicity and roughness. Histological analysis demonstrated significant osteogenic activity and basal bone formation, with well-formed bone plates observed at 6 weeks for implants coated with 20% collagen and 20% PCL. Novelty: The study highlights the potential of electrospun collagen/PCL coatings to create optimal surface properties for dental implants, achieving improved tissue integration and healing outcomes. This innovative approach demonstrates the versatility of electrospinning for fabricating fibrous scaffolds that can incorporate therapeutic agents, offering transformative implications for regenerative medicine and implantology.
INCIDENCE OF SEPSIS IN CHILDREN UNDER 5 YEARS OLD WITHIN KIRKUK PROVINCE Bazzaz, Ayoub A.; Rana W. Al-Hassan; A. Yassin; Noorhan A. Chelebi
Journal of Medical Genetics and Clinical Biology Vol. 2 No. 5 (2025): Journal of Medical Genetics and Clinical Biology
Publisher : PT. Antis International Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61796/jmgcb.v2i5.1317

Abstract

Objectives: Medical researches on septicemia, particularly, in most susceptible age group of children i.e. newborns and young infants in Iraq are scanty. The aim of this study is to assess the incidence of blood poisoning via hematological parameters in children under 5 years old within Kirkuk Province. Methodology: Only 120 children aged 1-60 months admitted to hospital on suspicion of blood poisoning were selected and compared with other 40 healthy children of similar ages used as control. Results: Almost 42.5% of suspected cases admitted to hospital were diagnosed sepsis positive. Over 80% of affected sepsis cases were in children aged 1-18 months old but dropped down as the age advanced. The main blood parameters i.e. leucocytes (WBC), erythrocytes (RBC), hemoglobin (Hb%), Lymphocytes (L), Blood platelets (PLT) were significantly (p≤0.05-0.0001) affected up and down in sepsis patients in comparison with counterpart children. Novelty: It is concluded that the newborn and infants are more susceptible to infection than older ages due to the immaturity of the immune system in these babies, artificial rather than breast feeding, negligence and inexperience of mothers and deficiency of hygienic parameters applied. Early and regular health checkup of newborn babies under 5 years old by pediatricians deems mandatory to promote health measurements and reduce children mortality.
INCIDENCES OF ACUTE APPENDICITIS CAUSED BY VARIOUS PARASITES WITHIN KIRKUK PROVINCE, IRAQ Bazzaz, Ayoub A.; Shaaban, Ruwaida E.; Kopurlu, Sa’ad A.Y.; Al-Basheer, Nada T.; Chelebi, Noorhan A.
Journal of Medical Genetics and Clinical Biology Vol. 2 No. 12 (2025): Journal of Medical Genetics and Clinical Biology
Publisher : PT. Antis International Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61796/jmgcb.v2i12.1500

Abstract

Objective: Acute appendicitis (AA) may initiate due to various agents including bacteria, parasites, mainly Enterobius vermicularis and others meanwhile studies on its etiology are so rare in Iraq. Method: This research involves 50 specimen undergone appendectomies presented with clinical symptoms of AA investigated for various parasites. Results: Four different parasites with various proportions were detected in the 50 appendectomies patients. Almost 27(54%) of cases were diagnosed negative or non-parasitic infection while only 23(46%) were diagnosed infected with various parasites e.g. Entamoeba histolytica, with highest prevalence 12(24%); followed by Enterobius vermicularis with 8(16%); Blantidium coli 2(4%) and finally Ascaris lumbricus 1(2%). Novelty: The percentage of infection by E. vermicularis denotes the highest international record as the main cause of acute appendicitis worldwide which might be interpreted as a most pandemic parasite in poor food hygiene conditions in Iraq. Appendicitis displayed almost no impact on blood parameters. Extra parameters should be adopted to monitor the hygiene of Iraqi local restaurants or takeaways serve the exposed food for public consumption.
Co-Authors A. Yassin Al-Basheer, Nada T. Al-Bayati, Shanai Azeez, Sarah T. Bayatli, Feedan J. Chelebi, Noorhan A. Jabur, Akram Jassim, Raghdaa Kopurlu, Sa’ad A.Y. Noorhan A. Chelebi Rana W. Al-Hassan Shaaban, Ruwaida E.