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TINJAUAN ARTIKEL : UJI MIKROBIOLOGI Nurul, Ahsana; Setiawan, Iwan; Yusa, Delia; Trisna, Dhea; Halisa, Nur; Putri, Odilia; Ekawati, Oktavia; Umi, Yuliana; Ze Fanya
Jurnal Farmasi (Journal of Pharmacy) Vol. 12 No. 2 (2023): Jurnal Farmasi (Journal of Pharmacy), October 2023
Publisher : Sekolah Tinggi Ilmu Kesehatan Nasional & Pengurus Cabang Ikatan Apoteker Indonesia (IAI) Sukoharjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.373013/hawgpe84

Abstract

Microorganisms such as bacteria are one of the causes of disease that many patients suffer. Bacteria can easily reach food or pharmaceutical preparations during the production process, so it is important to carry out antibacterial testing on a product to ensure product safety and quality. The activity of an antibacterial can be observed by several methods such as diffusion, dilution and broth microdilution. The purpose of this article review is to provide information regarding microbiological tests that can be used to test antibacterial activity. The method used is an online search for international journal literature using online search sites such as Google schoolar, Pubmed and Scopus. Various studies have found, it is known that the antibacterial activity test consists of three types. The first diffusion method consisting of a diffusion disc and wells. The purpose of the diffusion method is to determine the sensitivity and resistance of a bacterium to antibiotics. The two dilution methods consist of solid dilution and liquid dilution. The purpose of the dilution method is to determine the Minimum Inhibitory Concentration (MIC) and Minimum Killing Concentration (MBC). The effective microdilution of the three broths was used to determine the Minimum Inhibitory Concentration (MIC) and Minimum Kill Concentration (MBC). In the antibacterial activity test a bacterial inhibition zone will appear which will be measured according to the results. The size of the diameter of the inhibition zone will increase with increasing concentration of antibiotics.
Hubungan Antara Tingkat Pengetahuan dengan Tingkat Kepatuhan Penggunaan Obat Antihipertensi di Instalasi Rawat Jalan RS UNS: Jurnal Farmasi (Journal of Pharmacy), October 2025 Ekawati, Oktavia; Hartono; Dian Anggraini, Truly
Jurnal Farmasi (Journal of Pharmacy) Vol. 14 No. 2 (2025): Jurnal Farmasi (Journal of Pharmacy), October 2025
Publisher : Sekolah Tinggi Ilmu Kesehatan Nasional & Pengurus Cabang Ikatan Apoteker Indonesia (IAI) Sukoharjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.373013/m9kx3655

Abstract

Hypertension is still the largest disease in Central Java Province in the first quarter of 2023 at 63%. Various efforts to reduce mortality and morbidity due to hypertension have been carried out on a massive scale. The success of treating hypertension is influenced by a number of factors. An example of factors that have an impact is the patient's level of knowledge and understanding of hypertension and patient compliance in undergoing treatment. Knowledge and understanding are very necessary for patients to understand what to do and avoid so that treatment is successful. Compliance with hypertension treatment is important to monitor blood pressure and avoid complications. The research was conducted with the aim of determining the relationship between the level of knowledge and compliance with the use of antihypertensive drugs at UNS Sukoharjo Hospital. The study carried out was a cross-sectional type of research using a questionnaire. Compliance was measured using ARMS (Adherence to Refills and Medication Scale). The sampling technique used is purposive sampling which has inclusion provisions: patients who seek treatment in January-March 2024, undergo routine examinations. The number of samples that met the inclusion and exclusion requirements was 178 patients. Data analysis carried out the Spearman rank correlation test. The study findings show that patients who have a poor level of knowledge about hypertension and its treatment are 4.5%, a sufficient level of understanding is 28.1% and a good level of understanding is 67.4%. The level of patient compliance in using antihypertensive drugs in the low category was 62.4% and in the high category was 37.6%. The results of the Spearman rank correlation test obtained a p value of 0.000 (<0.05) which has a correlation value of 0.262. This indicates that there is a relationship with weak correlation strength on the level of knowledge and compliance in using antihypertensive drugs in the outpatient installation of UNS Sukoharjo Hospital.