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Tinjauan Pola Penggunaan Antibiotik Pada Pasien Anak Demam Tifoid di Instalasi Rawat Inap RSUP dr. Kariadi Semarang Tahun 2009 Dian Anggraini, Truly
Jurnal Farmasi (Journal of Pharmacy) Vol. 2 No. 1 (2013): Jurnal Farmasi (Journal of Pharmacy), October 2013
Publisher : Jurnal Farmasi (Journal of Pharmacy)

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Typhoid fever including one of disease the infection found many in developing countries with high density and also health of low environment. Pursuant to report WHO mentioned that Indonesia is one of the State with number occurence of high typhoid fever, that is > 100 per 100.000 resident per year. Epidemiology study is recently show to start the existence of risk multi drug resisten (MDR) at usage of antibiotic for the medication of typhoid fever. So that this research is done to know the pattern usage of antibiotic at typhoid fever child patient in Installation of Hospitalization RSUP Dr. Kariadi Semarang in the year 2009. This research is non-experimental. The data was collected retrospectively from patient medical records. Counted 100 sampel obtained, and the results were analyzed using descriptive non-analytic method. Patterns of use of antibiotics for typhoid fever seen through a class of antibiotics used, the presence or absence of antibiotics during replacement therapy, a combination of antibiotics given, route of administration, duration of antibiotics, antibiotic side effects, and drug interactions that occur due to the use of antibiotics. Research result indicate that at period of year of 2009 in Installation of Hospitalization RSUP Dr. Kariadi typhoid fever predominated by men patient at spanning the age of 6-10 year. The Antibiotic faction at most used is from faction sefalosporin equal to 55,22%, from 100 case of 35 between natural it’s of replacement antibiotic, usage of antibiotic combination equal to 50%, supply of antibiotic more given in the form of hypodermic and for the giving of antibiotic there are to don’t according giving of antibiotic at patient with written Standard Procedure Operational that is much more brief.

EVALUASI PENGARUH KESESUAIAN TERAPI HIPERTENSI DENGAN GUIDELINE JNC 7 TERHADAP TERCAPAINYA TARGET TEKANAN DARAH PASIEN DI RS PANTI WALUYO SURAKARTA PERIODE JANUARI-DESEMBER 2013 Dian Anggraini, Truly; Puspita Sari, Ika; Probosuseno
Jurnal Farmasi (Journal of Pharmacy) Vol. 5 No. 1 (2016): Jurnal Farmasi (Journal of Pharmacy), October 2016
Publisher : Jurnal Farmasi (Journal of Pharmacy)

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Hypertension is a major public health problem worldwide and is the most common risk factor for cardiovascular disease. The prevalence of hypertension in the population aged 18 years and above at 29.8%. Epidemiological data indicates that an increase of blood pressure would improve cardiovascular events. Therefore, hypertension should be treated appropriately by controlling blood pressure. This research aims to evaluate the effect of appropriateness of therapy hypertension based on JNC7 guideline in order to gain targeted blood pressure in RS Panti Waluyo Surakarta during January-December 2013. This study conducted using cohort retrospectively in inpatients medical record in RS Panti Waluyo Surakarta. A total of 116 samples were analyzed with descriptive-analytic method. Both monotherapy and combination of anti-hypertension drug were analyzed with JNC 7 guideline while the target blood pressure were statistically analized using Chi-square test. This research result showed that 50 patients exhibited the appropriate anti-hypertension therapy, while 66 patients showed the inappropriate anti-hypertension therapy. The pattern of anti-hypertension was that 38 patients prescribed single anti-hypertension medicine, 34 patients prescribed combination of 2 anti-hypertension medicine. Like the patients in appropriate group (66%), there were (47%) patients in inappropriate group could achive the target of blood pressure. In conclusion, there is a significant relationship between appropriateness of anti-hypertension use and target blood pressure (p <0.05).

PENGARUH RASIONALITAS PENGGUNAAN ANTIHIPERTENSI DENGAN STANDART GUIDELINE JNC 8 TERHADAP KEBERHASILAN TERAPI HIPERTENSI DI RS PANTI WALUYO SURAKARTA Dian Anggraini, Truly; Wisnu Kusuma, Eka; Diandari, Deswinda
Jurnal Farmasi (Journal of Pharmacy) Vol. 6 No. 1 (2017): Jurnal Farmasi (Journal of Pharmacy), October 2017
Publisher : Jurnal Farmasi (Journal of Pharmacy)

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Hypertension is one of the main problems of public health in the whole world and a factor tersering the risks of cardiovascular diseases .The prevalence of hypertension in the population of 18 years and older age of 29,8 % .An epidemiological data shows that a rise in blood pressure will increase the cardiovascular diseases, must be treated with proper and hypertension. The study aimed to identify the influence of rationality use of antihypertensives to the standard guideline jnc 8 to successful therapy hypertension in the hospital at waluyo surakarta year 2016 . The research is research cohort where over the withdrawal of funds data was undertaken in the manner of a retrospective from the records of record medical exam patients hypertension as an in patient in the year 2016 .After the recent retrieval of so sample will be analyzed the usage patterns antihypertensive drug as well as rationality the use of antihypertensive drug with a standard guideline jnc 8 have been analyzed in the manner of a diskriptif, the influence of rationality the use of antihypertensive drug with a standard guideline jnc 8 to successful ( therapy the point of view of achieve the target of the pressure of the blood patients ) have been analyzed is statistically use chi-square. The results of the study , 84 patients get therapy hypertension that is rational in accordance with guideline jnc 8 and 16 patients get therapy hypertension that is irrational with guideline jnc 8. The pattern of an antihypertensive drug, 52 patients prescribed an antihypertensive drug only begotten or unique son, 43 patients a combination 2 an antihypertensive dru , this is more than the patients prescribed more than 2 antihypertensive drug .The success of thera, 65 the patient from 84 cases of patients who get therapy hypertension that is rational managed to reach the target the pressure of the blood and he received treatment therapy assessed as being successful. A significant relation exists between rationality therapy hypertension with guideline jnc 8 against ketercapaian the success of therapy ( p<0,05 ).

Gambaran Penggunaan Obat Pada Hepatitis A Pasien Rawat Inap di Rumah Sakit Umum Daerah dr. Soediran Mangun Sumarso Wonogiri Periode Januari 2017 – Juni 2019 Noor Hidayati, Listiana; Dian Anggraini, Truly
Jurnal Farmasi (Journal of Pharmacy) Vol. 9 No. 1 (2020): Jurnal Farmasi (Journal of Pharmacy), April 2020
Publisher : Jurnal Farmasi (Journal of Pharmacy)

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Hepatitis A is an infectious disease of the liver caused by the hepatitis A virus. Number of cases of hepatitis A inpatients at the Regional General Hospital dr. Soediran Mangun Sumarso Wonogiri during 2017 - June 2019 as many as 110 patients. The purpose of this study was to determine the description of drug use in hepatitis A patients including the characteristics and treatment of patients. This research is a non-experimental study with a descriptive analysis design, by collecting data information through medical records of hepatitis A patients diagnosed in the period January 2017 - June 2019. The parameters used are the percentage of the characteristics of hepatitis A patients calculated based on age, sex, type of comorbidities and description of treatment of hepatitis A patients including the type and amount of drug used, the type and amount of infusion fluid used. The results showed that the percentage based on the age of patients with the most age range ≥ 56 years (30.91%), the percentage based on the most sexes of men (55%), the percentage based on the types of comorbidities with most types of typhoid disease (53.33%) , the percentage based on the use of drugs that are widely used is curcuma (12.37%), and the percentage based on the use of most intravenous fluids is ringer acetate (58.78%).

KESESUAIAN ASEPTIK DISPENSING INJEKSI ANTIBIOTIK PADA PASIEN ANAK RUMAH SAKIT UMUM DAERAH DR. SOEDIRAN MANGUN SUMARSO WONOGIRI Rusmiyati, Eny; Dian Anggraini, Truly
Jurnal Farmasi (Journal of Pharmacy) Vol. 11 No. 2 (2022): Jurnal Farmasi (Journal of Pharmacy), October 2022
Publisher : Sekolah Tinggi Ilmu Kesehatan Nasional & Pengurus Cabang Ikatan Apoteker Indonesia (IAI) Sukoharjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.373013/hvvtre46

The use of injection preparations in hospitalized patients has a high prevalence rate so that dispensing injections needs attention because there are many risks that can arise during the mixing process. The purpose of the study was to determine the suitability of the aseptic procedure for dispensing antibiotics in pediatric patients with standard operating procedures applicable at the dr. Sudirman Mangun Sumarso Wonogiri. This study used a retrospective method with descriptive analysis of the data for August – October 2021. Conformity was measured using a checklist form and the percentage of conformity was calculated. The results showed that from 106 antibiotic mixtures consisting of Cefotaxim inj (46%), Ceftriaxon inj (12%), Chloramphenicol inj (3%), and Gentamicin inj (39%) obtained 85.71% according to standard operating procedures. Compliance that has met the standard includes reviewing prescriptions, doing 5 correct, calculating dosage suitability, choosing solvents, calculating solvent volumes, making delivery forms and those that are not appropriate, namely checking the condition of the drug when it is received. Examination of the condition of the drug when it is received should be carried out accompanied by a form so that there is a record that can be used for tracing when a medication error occurs.

KAJIAN ETNOFARMASI PENGGUNAAN TUMBUHAN OBAT SEBAGAI ALTERNATIF PENGOBATAN DIARE OLEH MASYARAKAT SUKU OSING DUSUN KRAJAN Septa, Amira; Hartono; Dian Anggraini, Truly
Jurnal Farmasi (Journal of Pharmacy) Vol. 12 No. 1 (2023): Jurnal Farmasi (Journal of Pharmacy), April 2023
Publisher : Sekolah Tinggi Ilmu Kesehatan Nasional & Pengurus Cabang Ikatan Apoteker Indonesia (IAI) Sukoharjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.373013/rn63em44

Diarrhea is a disease that is still a health problem worldwide, including Indonesia. Diarrhea is included in the top 10 diseases that still occur frequently and is ranked 5th in the Osing Tribe. The Osing tribe community treats diarrhea by utilizing plants as medicinal plants that are used from generation to generation. This study was conducted to determine the use of ethnopharmaceuticals in the Osing tribe as a preliminary study for the development of traditional medicine by the Osing tribe as a standardized herbal medicine or phytopharmaca. This research is a descriptive study using qualitative methods with snowball sampling techniques through open- ended interviews with filling out informant information sheets and involving 22 community informants from the Osing tribe, Krajan Hamlet, Kemiren, Glagah, Banyuwangi, East Java. The results of ethnopharmaceutical research in the Osing tribe showed that there were 8 types of plants used for the treatment of diarrhea. Analysis using ICF (Informant Consensus Factor) with a result of 0.6 means that the plant is trusted and used as a hereditary treatment of diarrhea treatment. In the PPV (Plant Part Value) value analysis, which is to calculate the part of the plant used, the results obtained were 50% of the leaves, 23% of the fruit, 27% of the rhizome. Fidelity Level (FL) to determine the type of plant that is most often used in treating diarrhea with the highest result of 100% from among others Guava (Psidium guajava L.) and Cassava (Manihot esculenta).

Hubungan Antara Tingkat Pengetahuan dengan Tingkat Kepatuhan Penggunaan Obat Antihipertensi di Instalasi Rawat Jalan RS UNS: Jurnal Farmasi (Journal of Pharmacy), October 2025 Ekawati, Oktavia; Hartono; Dian Anggraini, Truly
Jurnal Farmasi (Journal of Pharmacy) Vol. 14 No. 2 (2025): Jurnal Farmasi (Journal of Pharmacy), October 2025
Publisher : Sekolah Tinggi Ilmu Kesehatan Nasional & Pengurus Cabang Ikatan Apoteker Indonesia (IAI) Sukoharjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.373013/m9kx3655

Hypertension is still the largest disease in Central Java Province in the first quarter of 2023 at 63%. Various efforts to reduce mortality and morbidity due to hypertension have been carried out on a massive scale. The success of treating hypertension is influenced by a number of factors. An example of factors that have an impact is the patient's level of knowledge and understanding of hypertension and patient compliance in undergoing treatment. Knowledge and understanding are very necessary for patients to understand what to do and avoid so that treatment is successful. Compliance with hypertension treatment is important to monitor blood pressure and avoid complications. The research was conducted with the aim of determining the relationship between the level of knowledge and compliance with the use of antihypertensive drugs at UNS Sukoharjo Hospital. The study carried out was a cross-sectional type of research using a questionnaire. Compliance was measured using ARMS (Adherence to Refills and Medication Scale). The sampling technique used is purposive sampling which has inclusion provisions: patients who seek treatment in January-March 2024, undergo routine examinations. The number of samples that met the inclusion and exclusion requirements was 178 patients. Data analysis carried out the Spearman rank correlation test. The study findings show that patients who have a poor level of knowledge about hypertension and its treatment are 4.5%, a sufficient level of understanding is 28.1% and a good level of understanding is 67.4%. The level of patient compliance in using antihypertensive drugs in the low category was 62.4% and in the high category was 37.6%. The results of the Spearman rank correlation test obtained a p value of 0.000 (<0.05) which has a correlation value of 0.262. This indicates that there is a relationship with weak correlation strength on the level of knowledge and compliance in using antihypertensive drugs in the outpatient installation of UNS Sukoharjo Hospital.

ANALISIS SWAMEDIKASI OBAT ANALGETIK PADA PENDERITA SAKIT GIGI DI MASYARAKAT CEMANI KECAMATAN GROGOL KABUPATEN SUKOHARJO Mursiany, Anita; Nur Khasanah, Isna; dian anggraini, Truly
Jurnal Locus Penelitian dan Pengabdian Vol. 2 No. 8 (2023): Jurnal Locus Penelitian dan Pengabdian
Publisher : Riviera Publishing

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58344/locus.v2i8.1329

Obat analgetik diketahui dapat mengurangi rasa nyeri yang disebabkan sakit gigi. Obat analgetik non narkotik bisa diperoleh di apotek dengan resep maupun tanpa menggunakan resep. Kemudahan dalam mengakses informasi di internet membuat masyarakat memilih untuk melakukan swamedikasi (pengobatan sendiri). Tujuan dari penelitian ini adalah untuk mengetahui swamedikasi penggunaan obat analgetik pada pasien sakit gigi di masyarakat cemani, kecamatan grogol, kabupaten sukoharjo. Penelitian menggunakan rancangan deskriptif observasional. Sampel penelitian dipilih secara purposive sampling sesuai kriteria inklusi dan eksklusi, jumlah responden sebanyak 100 orang. Instrument penelitian ini menggunakan teknik wawancara terstruktur. Kriteria inklusi adalah responden berusia > 17 tahun, responden pernah menderita sakit gigi, dan responden membeli obat di apotek tanpa resep. Hasil dari penelitian jenis obat analgetik yang banyak digunakan adalah asam mefenamat sebanyak 36 %, paracetamol sebanyak 19 %, kalium diklofenak sebanyak 23 %, natrium diklofenak sebanyak 12 %, ibuprofen 7 %, asetosal 1%, dan obat kombinasi paracetamol dan kafein sebanyak 1 %.

PENETAPAN KADAR FLAVONOID TOTAL INFUSA RAMBUT JAGUNG MANIS (Zea mays Saccharata Sturt) MENGGUNAKAN SPEKTROFOTOMETRI UV-VIS SECARA KOLORIMETRI Mursiany, Anita; Olivia Umboro, Recta; Dian Anggraini, Truly
Jurnal Locus Penelitian dan Pengabdian Vol. 2 No. 12 (2023): jurnal locus penelitian dan pengabdian
Publisher : Riviera Publishing

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58344/locus.v2i12.2354

Rambut jagung manis selama ini dianggap sebagai limbah dan belum dimanfaatkan secara optimal. Hasil penelitian menunjukkan bahwa ekstrak air rambut jagung muda umur 40 hari dan rambut jagung umur 60 hari mengandung senyawa flavonoid, alkaloid, saponin, tanin, dan fenol. Penelitian ini bertujuan untuk mengetahui kandungan total flavonoid pada infusa rambut jagung manis (Zea mays Saccharata Sturt). Metode penelitian yang digunakan adalah penentuan kadar flavonoid total yang dilakukan secara Spektrofotometri UV-Vis secara kolorimetri. Kandungan total flavonoid dalam (mgQE/g ekstrak) berturut-turut adalah 0,0061, 0,0047, 0,0085, dan dalam persen (%) 0,61, 0,47, 0,85. Sehingga dapat disimpulkan bahwa infusa rambut jagung manis (Zea mays Saccharata Sturt) mengandung senyawa flavonoid dan rata-rata kadar flavonoid total sebesar 0,0064 ± 0,0019 mgQE/g ekstrak dengan persentase sebesar 0,6433 ± 0,1921%.

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