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All Journal Jurnal Mandala Pharmacon Indonesia
Fadila, Nikma
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Medicine & Pharmacology

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Formulasi Glowing Acne Cream Ekstrak Daun Nipah (Nypa fruticans) Sebagai Produk Untuk Mencegah Pertumbuhan Jerawat Dan Memperbaiki Skin Barrier Adillah, Fadya; Mursyid, Murni; Astari, Chitra; Rahmah, Andi Fikrah; Muthmainnah, Nur Hikmah; Fadila, Nikma
Jurnal Mandala Pharmacon Indonesia Vol. 10 No. 1 (2024): Jurnal Mandala Pharmacon Indonesia
Publisher : Program Studi Farmasi Universitas Mandala Waluya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35311/jmpi.v10i1.488

Abstract

One of the skin problems that often occurs among teenagers today is acne. Acne treatment generally uses antibiotics which can have side effects in the form of irritation or resistance if used long term. Therefore, another alternative is needed in treating acne, namely using natural ingredients which are expected to minimize the side effects of using antibiotics. A natural ingredient that is efficacious as an acne medicine is nipah leaves (Nypa fruticans) which contain flavonoid compounds which function as antibacterial agents. The aim of this research is to determine the physical properties test and at what concentration the glowing acne cream preparation of nipah leaf extract (Nypa fruticans) is effective against Propionibacterium acnes bacteria. The research results showed that the organoleptic test, homogeneity test, pH test, spreadability test, stickiness test, cream type test, viscosity test had fulfilled the preparation evaluation requirements. In the irritation test for all formulas all respondents had negative results and in the hedonic test for F1 color was preferred, aroma and shape were preferred by respondents in F2. Meanwhile, in the antibacterial activity test for the very strong category, it was found in F1 with an inhibitory zone diameter of 20.16mm and for the results of statistical analysis using one way ANOVA, the value P=0.000 was obtained
Formulasi dan Uji Stabilitas Fisik Sediaan Lip Balm Ekstrak Etanol Buah Coppeng (Syzigium cumini) Sebagai Antioksidan fadila, nikma
Jurnal Mandala Pharmacon Indonesia Vol. 10 No. 1 (2024): Jurnal Mandala Pharmacon Indonesia
Publisher : Program Studi Farmasi Universitas Mandala Waluya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35311/jmpi.v10i1.493

Abstract

ABTRACT Lips are a sensitive part of the face, unlike other skin which has protection, lips do not have protection. When the air is too hot or too cold, lips become dry, chapped, and painful. Therefore, you need an alternative to care for your lips, namely by using lip balm or lip moisturizer made from natural ingredients. A natural ingredient that is rich in antioxidants is coppeng fruit (Syzigium cumini). Anthocyanin compounds, phenolic acids, flavonoids and tannins of coppeng fruit (Syzigium cumini) are active compounds that function as antioxidants. Therefore, lip balm is made from coppeng fruit as an antioxidant to treat lip problems. The aim of this research is to determine the physical properties and at what concentration the coppeng fruit extract (Syzigium cumini) lip balm preparation functions as an antioxidant agent, whether F1, F2 or F3. The antioxidant activity test was carried out using the DPPH method. The results of the research showed that in the organoleptic test F0, F1, F2 and F3 met the requirements, namely semi-solid dosage form, the color of F1 was light purple, F2, F3 was dark purple and had a distinctive vanilla aroma. All preparations showed homogeneous results. The average pH test of the preparation was 5.25, the average adhesion test was 5.76/second, the irritation test on F0, F1, F2 and F3 did not irritate all respondents and the most preferred hedonic test was F1. In the antioxidant activity test, the IC50 value for F1 was 86.63989 µ/ml in the strong category, F2 was 49.3719 in the µ/ml category and F3 was 4.603502 in the very strong category. Key words: lip balm preparation, coppeng fruit, antioxidant agent
Co-Authors Adillah, Fadya Astari, Chitra Mursyid, Murni Muthmainnah, Nur Hikmah Rahmah, Andi Fikrah