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Potential of Kopasanda Leaf Ethanol Extract as Anti-Hyperglycemia Hartati; Sahribulan, Sahribulan; Duprah, Nur Awaliah
Jurnal Biologi Tropis Vol. 24 No. 4 (2024): Oktober - Desember
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v24i4.7921

Abstract

Indonesia has various types of plants that grow and spread naturally that have the potential as medicinal plants. Plants that are commonly used by the community as medicinal ingredients are kopasanda (Chromolaena odorata L.) or known as kirinyu. Kopasanda leaves contain several main compounds such as tannins, phenols, flavonoids, saponins and steroids. Essential oils from the leaves contain isomers of α-pinene, cadinene, camphora, limonene, β-caryophyllene and candinol. The flavonoid group has antioxidant activity including flavones, flavonols, isoflavols, isoflavones, cathexins, and chalcones, so that kopasanda leaves are rich in antioxidants that can lower blood glucose levels. According to the above description, the researcher will investigate the potential benefits of kopasanda leaf ethanol extract as an anti-hyperglycemia agent in mice. In this study, kopasanda leaves are extracted using an ethanol solvent, and the effect of the extract on the blood glucose levels of mice is tested. According to the findings, kopasanda leaf ethanol extract at a dose of 150 mg/kgBW significantly reduced blood glucose levels by 54.99%. The administration of kopasanda leaf extract significantly lowers blood glucose levels in mice, according to the findings. The ethanol extract of kopasanda leaves at a concentration of 150% is the most effective at lowering blood glucose levels, with a 54.99% reduction.
Epistemology of Biology Education in The Technology Era: from Real Experiments to Virtual Laboratories Duprah, Nur Awaliah; Ismail, Ismail
Biology Teaching and Learning Vol 8, No 2 (2025): December
Publisher : Universitas Negeri Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35580/btl.v8i2.78018

Abstract

Abstract. Digital transformation in biology education has resulted in fundamental changes in how scientific knowledge is understood, constructed, and validated by students. This article examines new directions in the epistemology of biology education through a review of 24 articles discussing epistemic cognition, epistemic practices, the use of virtual laboratories, and the shift from real experiments to digital environments. The research method used a literature review with thematic analysis on three focuses: the epistemology of biology education in the technological era, the reconstruction of experimental experiences in virtual laboratories, and the epistemological implications of using technology in biology learning. The results of the study show that technology changes the representation of knowledge and influences the way students interpret evidence, construct arguments, and understand scientific processes, as indicated by the analysis of 24 articles, around 60% of which highlight the shift in experimental practices from real laboratories to virtual laboratories. Virtual laboratories offer advantages in terms of accessibility, visualization, and variable control, but pose epistemic challenges related to the validity of evidence and the potential for misrepresentation. This study emphasizes the need for a hybrid epistemological approach that integrates direct empirical experience with technology-based learning to shape epistemic literacy relevant to the demands of the digital age. Keywords: biology education, digital epistemology, epistemic cognition,, virtual laboratory