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All Journal IJRETINA - International Journal of Retina Cermin Dunia Kedokteran
Pratiwi, Karina Satyani
Unknown Affiliation
Health Professions Medicine & Pharmacology Public Health

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Single Arterial Oxygen Tension Elevation Increases the Risk of Stage of Acute Disease Retinopathy of Prematurity Pratiwi, Karina Satyani; Yulia, Dian Estu; Barliana, Julie Dewi; Sitorus, Rita Sita
International Journal of Retina Vol 6 No 2 (2023): International Journal of Retina (IJRetina) - INAVRS
Publisher : Indonesian Vitreoretinal Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35479/ijretina.2023.vol006.iss002.242

Abstract

Introduction: Numerous studies have shown inconclusive results regarding ideal parameter for oxygen supplementation to balance the risk of mortality and retinopathy of prematurity (ROP) development. The purpose of this study is to compare mean partial oxygen tension (PaO2) level in ROP. Methods: This retrospective study was performed on premature infants undergoing ROP screening at our neonatal intensive care unit during 2021. All infants born at our hospital at ≤ 30 weeks, birth weight (BW) ≤ 1500 grams, or high-risk infants with prolonged ventilation were included. ROP screening was performed at chronological age four to six weeks, were followed and managed according to the severity. ROP severity was categorized by International Classification of ROP 3rd edition (ICROP3). We reviewed the characteristics of each group and compared mean PaO2 level in day 1, day 5, and day 10 between incomplete vascularization (IV) group, stage of acute disease (SAD) group, and Aggressive ROP (A-ROP) group. Result: We investigated 124 eyes from 62 eligible PI. The incidence of IV, stage 1, stage 2, stage 3, and A-ROP were 58.9%, 2.4%, 7.3%, 23.4%, and 8.1%, respectively. Mean PaO2 level in day 5 was higher in SAD group compared to IV group (p=0.002). For each level increase in PaO2, there was 1.042 times higher odds of developing SAD (p=0.004). Multivariate logistic regression analysis showed consistent results, simultaneously, each week increase in GA was associated with lower risk of SAD development (p=0.018) and each level increase in PaO2 was associated with higher risk for SAD development (p=0.005). Conclusion: A single elevation in PaO2 during early life of PI increases the risk of developing stage of acute disease ROP, particularly in younger infants. Careful monitoring for PaO2 is mandatory to prevent development of ROP.
Kesadaran Orang Tua terhadap Aplikasi Berbasis Ponsel Pintar untuk Anak-Anak Tunanetra dan Tuli di Yogyakarta, Indonesia: Penelitian Pratiwi, Karina Satyani; Arjana, Adika Zhulhi; Ratnaningrum, Ayu Yunita; Sabana, Manusama Hasan; Chamidah, Atien Nur
Cermin Dunia Kedokteran Vol 53 No 05 (2026): Kedokteran Umum
Publisher : PT Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55175/cdk.v53i05.1823

Abstract

Introduction: Smartphone-based applications (SBA) are currently available to help children with visual impairment (VI) and blindness progress to the next level of learning. This study aims to explore parental awareness of SBA to support the learning process of their visually impaired children. Methods: A cross-sectional study involving 27 children with VI and blindness. Parents were sent a questionnaire to be completed. The 20-item questionnaire measured the history of their children’s general and eye health, and SBA awareness and use, if any. Children were examined for general health and current eye conditions. Results: Blindness was 92.9%. The most common cause of blindness was retinopathy of prematurity. The majority went to a special school for the blind. Parents’ education level was mostly high school graduates. Only 22.2% parents were aware of the existence of SBA for children with VI and blindness. Conclusion: Parental awareness regarding smartphone-based applications (SBA) for children with VI and blindness was low.
Co-Authors Adika Zhulhi Arjana Atien Nur Chamidah Estu Yulia, Dian Julie Dewi Barliana Ratnaningrum, Ayu Yunita Sabana, Manusama Hasan Sitorus, Rita Sita