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All Journal Jurnal Ilmu Kedokteran dan Kesehatan Indonesia
Rizka Wahyu Syahputra
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Health Professions Public Health

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Evaluasi Penggunaan dan Outcome Terapi Obat Antinyeri pada Pasien Diabetik Neuropati di RS PKU Muhammadiyah Surakarta Rahayu Putri Priyanda; Vivin Marwitari Rohmana; Rizka Wahyu Syahputra
Jurnal Ilmu Kedokteran dan Kesehatan Indonesia Vol. 5 No. 3 (2025): November : Jurnal Ilmu Kedokteran dan Kesehatan Indonesia
Publisher : Pusat Riset dan Inovasi Nasional

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/jikki.v5i3.8288

Abstract

Diabetic neuropathy is a type of neuropathic pain commonly found in patients with diabetes, resulting from damage to the central or peripheral nervous system. Neuropathic pain is one of the most frequent and distressing symptoms experienced by patients with diabetic peripheral neuropathy, affecting approximately 16% to 26% of patients. Neuropathic pain can significantly impact daily activities, self-care ability, work productivity, and sleep quality (Rivani et al., 2024). This study aimed to analyze the patterns of analgesic therapy use in patients with diabetic neuropathy and to evaluate the effectiveness of such therapy in reducing neuropathic pain levels. This study employed a retrospective observational design, using medical records data from January to December 2024. Data collected included patient characteristics, types and doses of analgesic drugs, and clinical outcomes based on pain improvement. Descriptive analysis and Chi-Square tests were performed. A total of 72 samples meeting the inclusion criteria were obtained. The evaluation of the use and outcomes of analgesic therapy in patients with diabetic neuropathy at PKU Muhammadiyah Hospital Surakarta revealed that the effectiveness of therapy was assessed based on patient outcomes after treatment. Most patients showed improvement in pain conditions, with Gabapentin demonstrating the highest effectiveness in reducing neuropathic pain. The Chi-Square test analysis on the relationship between the type of analgesic drug combination and the patient’s pain level after therapy yielded a significance value of 0.005. Since the significance value was <0.05, it can be concluded that there is a statistically significant relationship between the type of drug administered and the patient’s pain level after undergoing therapy.
Formulasi Sediaan Pomade dan Uji Efektivitas Ekstrak Daun Salam (Syzygium Polyanthum) terhadap Pertumbuhan Rambut Kelinci New Zealand White Putri Barlian Nur Cahyaning Tyas; Bangkit Riska Permata; Rizka Wahyu Syahputra
Jurnal Ilmu Kedokteran dan Kesehatan Indonesia Vol. 5 No. 3 (2025): November : Jurnal Ilmu Kedokteran dan Kesehatan Indonesia
Publisher : Pusat Riset dan Inovasi Nasional

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/jikki.v5i3.8332

Abstract

Bay leaves are known to contain flavonoids, tannins, saponins, and essential oils, which have been empirically proven to promote healthy hair. This study aimed to determine the potential of bay leaf extract (Syzygium polyanthum) as an active ingredient in pomade and its effectiveness on hair growth in New Zealand White rabbits. The research method used was an experimental laboratory with four variations of pomade formulations: F0 (without extract), F1 (20%), F2 (25%), and F3 (30%). Evaluations were conducted on physical quality parameters such as organoleptic properties, pH, homogeneity, spreadability, viscosity, and adhesion. Effectiveness testing was conducted on the rabbits' backs for 28 days, measuring hair growth. The results of the study showed that pomade preparations with bay leaf extract had physical qualities that met the requirements for hair growth with various extract effectiveness on the 28th day of peak testing showing Formula I (20%) 0.4 cm, formula II (25%) 0.4 cm, Formula III (30%) 1.0 cm, providing the highest hair growth results, namely Formula III compared to other formulas. The results of SPSS statistical analysis with a significance value <0.05 resulted in differences between treatments. So it can be concluded that bay leaf extract can be formulated into an effective pomade preparation in stimulating hair growth.
Co-Authors Bangkit Riska Permata Putri Barlian Nur Cahyaning Tyas Rahayu Putri Priyanda Vivin Marwitari Rohmana