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All Journal Jurnal Riset Rumpun Ilmu Kesehatan (JURRIKES) International Journal of Health, Engineering and Technology Detector: Jurnal Inovasi Riset Ilmu Kesehatan Jurnal Ilmu Kedokteran dan Kesehatan Indonesia
Bangkit Riska Permata
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Agriculture, Biological Sciences & Forestry Chemical Engineering, Chemistry & Bioengineering Dentistry Engineering Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Mechanical Engineering Medicine & Pharmacology Nursing Public Health Veterinary

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Formulation and Antibacterial Activity Test of Dragon Tail Leaf Extract Cream (Rhaphidophorapinnata (L.f) Schott) Against Staphylococcus aureus ATCC (25923) Mutia Della Citra; Bangkit Riska Permata; Kharisma Jayak Pratama
International Journal of Health Engineering and Technology Vol. 4 No. 3 (2025): IJHET SEPTEMBER 2025
Publisher : CV. AFDIFAL MAJU BERKAH

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

This study aims to formulate a cream containing Rhaphidophora pinnata (L.f) Schott leaf extract and evaluate its antibacterial activity against Staphylococcus aureus ATCC 25923. The background of this research is rooted in the potential of Indonesian medicinal plants and the increasing cases of antibiotic resistance, which drives the development of natural antibacterial agents. A quantitative experimental laboratory method was employed. The study population was the Rhaphidophora pinnata plant from Sragen, with a sample of 8 kg of fresh leaves. Antibacterial activity was tested using the disc diffusion method, and data were analyzed descriptively and inferentially using One-Way ANOVA with SPSS. The results showed that cream formulations at 10%, 30%, and 40% concentrations had physical qualities that met standards, including a safe pH (6.0–6.8) and stable viscosity. The antibacterial test demonstrated the highest activity at the 40% concentration, producing the largest inhibition zone against S. aureus. However, its efficacy was still lower than that of the positive control (gentamicin cream). In conclusion, R. pinnata leaf extract has the potential to be developed as a natural antibacterial cream, and further research is needed for stability and clinical testing.
Formulasi Sediaan Pomade dan Uji Efektivitas Ekstrak Daun Salam (Syzygium Polyanthum) terhadap Pertumbuhan Rambut Kelinci New Zealand White Putri Barlian Nur Cahyaning Tyas; Bangkit Riska Permata; Rizka Wahyu Syahputra
Jurnal Ilmu Kedokteran dan Kesehatan Indonesia Vol. 5 No. 3 (2025): November : Jurnal Ilmu Kedokteran dan Kesehatan Indonesia
Publisher : Pusat Riset dan Inovasi Nasional

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/jikki.v5i3.8332

Abstract

Bay leaves are known to contain flavonoids, tannins, saponins, and essential oils, which have been empirically proven to promote healthy hair. This study aimed to determine the potential of bay leaf extract (Syzygium polyanthum) as an active ingredient in pomade and its effectiveness on hair growth in New Zealand White rabbits. The research method used was an experimental laboratory with four variations of pomade formulations: F0 (without extract), F1 (20%), F2 (25%), and F3 (30%). Evaluations were conducted on physical quality parameters such as organoleptic properties, pH, homogeneity, spreadability, viscosity, and adhesion. Effectiveness testing was conducted on the rabbits' backs for 28 days, measuring hair growth. The results of the study showed that pomade preparations with bay leaf extract had physical qualities that met the requirements for hair growth with various extract effectiveness on the 28th day of peak testing showing Formula I (20%) 0.4 cm, formula II (25%) 0.4 cm, Formula III (30%) 1.0 cm, providing the highest hair growth results, namely Formula III compared to other formulas. The results of SPSS statistical analysis with a significance value <0.05 resulted in differences between treatments. So it can be concluded that bay leaf extract can be formulated into an effective pomade preparation in stimulating hair growth.
Formulasi Dan Uji Mutu Fisik Sediaan Bedak Padat Ekstrak Biji Bunga Matahari (Halianthus Annuus L.) Sebagai Antioksidan Ilham La Tansa; Bangkit Riska Permata; Kusumaningtyas Siwi Artini
Detector: Jurnal Inovasi Riset Ilmu Kesehatan Vol. 1 No. 4 (2023): November : Jurnal Inovasi Riset Ilmu Kesehatan
Publisher : Pusat Riset dan Inovasi Nasional

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/detector.v1i4.2517

Abstract

Sunflower (Halianthus annuus L.) is a flower that is widely consumed by the world's people. The part that is consumed from the sunflower is the seeds of the flower. Sunflower seeds have many useful ingredients in them, such as high nutritional value, being a good source of unsaturated fat, protein, inorganic compounds, vitamin E. One of the plants that has the potential as an antioxidant is sunflower (Halianthus annuus L.). The purpose of this study was to determine whether sunflower seed extract pressed powder (Halianthus annuus L.) had good physical quality, to determine whether sunflower seed extract pressed powder (Halianthus annuus L.) had antioxidant activity, to determine what concentrations of sunflower seed extract pressed powder (Halianthus annuus L.) had strong antioxidant activity as a good compact powder. Testing the antioxidant activity using the DPPH method with a positive control, namely vitamin c. The results of this study indicate that sunflower seed extract (Halianthus annuus. L) can be made into solid powder preparations, has an extract antioxidant activity of 96.78 μg/mL and has antioxidant activity when made into pressed powder preparations of 176.20 μg/mL with a concentration of 2.5%, 143.51 μg/mL with a concentration of 5%, and 121.22 μg/mL with a concentration of 7.5%.
Uji Aktivitas Antioksidan dan Penentuan Nilai Sun Protection Factor (SPF) Sediaan Lip Balm Ekstrak Kayu Secang (Caesalpinia Sappan L.) Nugrahaeni Ayuningtyas; Niken Luthfiyanti; Bangkit Riska Permata
JURNAL RISET RUMPUN ILMU KESEHATAN Vol. 4 No. 3 (2025): Desember : Jurnal Riset Rumpun Ilmu Kesehatan
Publisher : Pusat riset dan Inovasi Nasional

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/jurrikes.v4i3.6755

Abstract

Sappan wood (Caesalpinia sappan L.) is known to contain various bioactive compounds such as saponins, tannins, flavonoids, phenols, brazilin, and gallic acid. These compounds play an important role as antioxidants that can ward off free radicals and absorb UVA and UVB radiation that are harmful to the skin. Ultraviolet radiation is known to accelerate premature aging and cause tissue damage, so a topical formulation is needed that can provide protection while maintaining skin health. This study aims to determine the antioxidant activity and sunscreen ability of sappan wood extract in the form of lip balm with varying extract concentrations. Antioxidant activity was evaluated using the DPPH (1,1-Diphenyl-2-Picrylhydrazyl) method, while the Sun Protection Factor (SPF) value was determined by the Mansyur method using UV-Vis spectrophotometry. Sappan wood extract was formulated into four lip balm preparations, namely F0 (control without extract), F1 (5%), F2 (10%), and F3 (15%). Physical tests including homogeneity, pH, spreadability, adhesiveness, and organoleptic were conducted to ensure the quality of the preparation. The results showed that sappanwood extract had an IC50 value of 23.62 ppm which was categorized as very strong antioxidant activity. In the lip balm formulation, the IC50 values ​​obtained were F0 = 246.76 ppm (very weak), F1 = 92.68 ppm (strong), F2 = 78.03 ppm (strong), and F3 = 63.58 ppm (strong). The SPF test showed a protection value of F0 = 2.11 (minimum), F1 = 13.64 (maximum), F2 = 14.25 (maximum), and F3 = 18.28 (ultra). Thus, lip balm made from sappanwood extract has the potential as a cosmetic preparation that not only meets physical criteria, but also provides high antioxidant activity and effective sunscreen protection.
Co-Authors Ilham La Tansa Kharisma Jayak Pratama Kusumaningtyas Siwi Artini Mutia Della Citra Niken Luthfiyanti Nugrahaeni Ayuningtyas Putri Barlian Nur Cahyaning Tyas Rizka Wahyu Syahputra