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Identifikasi Mikroorganisme Bakteri Laktobasilus sp dari Hasil Permentasi Ikan Channa Striata (Ikan Gabus) Bathin VIII Sarolangun Jambi Muthiya Amalia; Ardi Mustakim
Konstanta : Jurnal Matematika dan Ilmu Pengetahuan Alam Vol. 3 No. 3 (2025): September : Jurnal Matematika dan Ilmu Pengelatuan Alam
Publisher : International Forum of Researchers and Lecturers

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59581/konstanta.v3i3.5362

Abstract

This study aims to identify Lactobacillus sp. bacteria obtained from the fermentation of Channa striata fish (snakehead fish) originating from Bathin VIII, Sarolangun, Jambi. Snakehead fish is known to have high protein content and bioactive compounds that support the growth of probiotic microorganisms, especially lactic acid bacteria (LAB). Fermentation was carried out naturally for several days under controlled conditions, then isolation and characterization of bacteria were carried out through culture techniques on de Man Rogosa Sharpe Agar (MRSA) media. Initial identification was carried out using colony morphology tests, Gram staining, and basic biochemical tests. The isolation results showed the presence of round, convex, and milky white colonies, and showed Gram-positive and rod-shaped properties, which are typical characteristics of Lactobacillus sp. This study indicates that fermented snakehead fish can be a natural source of Lactobacillus sp. isolates that have the potential to be developed as probiotics in functional foods or local fermented products. These findings are expected to contribute to the development of local microorganism-based food technology and increase the economic value of snakehead fish in the Jambi region. Further research is needed to test the functional potential and safety of the isolated strains.
Inovasi Terbaru dalam Terapi Gen, Terapi Berbasis Sel, dan Pengembangan Obat Anti Kanker dari Bahan Alam Muthiya Amalia; Ardi Mustakim
Jurnal Cakrawala Pendidikan dan Biologi Vol. 2 No. 1 (2025): Maret: Jurnal Cakrawala Pendidikan dan Biologi
Publisher : Asosiasi Riset Ilmu Pendidikan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61132/jucapenbi.v2i1.150

Abstract

Cancer therapy has undergone remarkable advancements in recent decades, driven by innovations in gene therapy, cell-based therapy, and the development of anti-cancer drugs from natural products. Gene therapy offers the possibility of correcting genetic mutations that cause cancer, while cell-based therapies, such as CAR-T cell therapy, provide personalized and effective solutions. Additionally, the exploration of natural compounds continues to be a promising approach in anti-cancer drug development. This paper discusses recent progress in these three fields, highlighting their potential, challenges, and implications for future clinical applications.