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Peran Filsafat Ilmu dalam Perkembangan Ilmu Pengetahuan di Era Perkembangan Zaman Dongoran, Rosita; Salsabila, Nur Ain; Ali, Fatimah; Rahmad, Ambia Perdana
As-Syirkah: Islamic Economic & Financial Journal Vol. 3 No. 2 (2024): As-Syirkah: Islamic Economic & Financial Journal 
Publisher : Ikatan Da'i Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56672/4v2t5581

Abstract

This study review saspect sof the philosophy of science that focuses on aspect sof the development of science in the era of the industrial revolution 5.0. The study used a qualitative research method with aliteratur estudy approach.The collection of relevant data information is taken from various library sources suchas;books,journals,news, internet in accordance with the topic of discussion. The results of this study were obtained by classifying the dimensions, elements, and sub-elements of the relationship between philosophy and science, philosophy based on its character and function, the relationship between the philosophy of science and other sciences, studying philosophy, science and the industrial revolution 5.0.    
THE EFFECT OF MICROMETRIC PROPERTIES AND SPECIFIC GRAVITY MEASUREMENT METHODS ON PHARMACEUTICAL RAW MATERIALS: A REVIEW Ali, Fatimah; Ilyas, Ika Lismayani; Pratiwi, Ines Septiani
Journal Pharmaceutical Science and Application Vol. 7 No. 1 (2025): Journal Pharmaceutical Science and Application
Publisher : Pharmacy Department, Math and Sciences Faculty, Udayana Univerity

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24843/JPSA.2025.v07.i01.p01

Abstract

Background: Tablet preparations consist of active substance compositions with or without additional substances (excipients). Micrometric properties are taken into consideration in the development of solid formulations because they can play a role in formulating formulations to obtain optimal therapeutic targets and ranges to form products that can be fully developed. In selecting a tablet manufacturing method, namely the direct compression method, it is very necessary to have a substance that has good flowability and compressibility. Objective: In this study, observations were made on the poor micrometric properties in order to increase the specific gravity of the particles used so that an optimal drug formulation is obtained. Methods: The writing method used is a comparative method by collecting various sources obtained from research journals from 2014-2024. Results: Observations of micrometric properties can increase along with modifications to substances or compounds, namely by using the carboxymethylation, crystallization, and agglomeration methods. Conclusion: Pharmaceutical raw materials that have poor micrometric properties can be improved by modifying them either through carboxymethylation, crystallization, or agglomeration processes. So that it can reduce the Carr index and increase the Hausner ratio of the material, then the specific gravity test provides information about the purity of the compound. Keywords: Micrometric; Specific gravity; Carboxymethylation; Crystallization; Agglomeration.