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All Journal Bioscientist : Jurnal Ilmiah Biologi
Kundera, I Negah
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Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Education Immunology & microbiology Social Sciences

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Pengaruh Ekstrak Tembuluk Kelapa Merah (Cocos nucifera var. rubescens) Terhadap Penurunan Kadar Glukosa Darah Pada Mencit (Mus musculus) Novi, Winda Cinthia; Sutrisnawati, Sutrisnawati; Ramadhan, Achmad; Trianto, Manap; Masrianih, Masrianih; Kundera, I Negah
Bioscientist : Jurnal Ilmiah Biologi Vol. 13 No. 2 (2025): June
Publisher : Department of Biology Education, FSTT, Mandalika University of Education, Indonesia.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33394/bioscientist.v13i2.16418

Abstract

This study aims to determine the effect of red coconut embryo extract (Cocos nucifera var. rubescens) on reducing blood glucose levels in mice (Mus musculus). The research employed a true experimental method using a completely randomized design (CRD). A total of 24 mice were used, divided into 6 groups with 5 replications each. The normal control group (KN) was given food and water ad libitum, while the positive control (K+), negative control (K−), and treatment groups (PI, PII, PIII) were induced with alloxan for 7 days. The positive control group (K+) was administered 1.3 mg of synthetic metformin per 20 grams of body weight. Both the normal control (KN) and negative control (K−) groups were given food and water ad libitum. The treatment groups PI, PII, and PIII were administered red coconut embryo extract at varying concentrations. Treatment group 1 (PI) received 40% extract, group 2 (PII) received 60%, and group 3 (PIII) received 80%. Observation data were analyzed using ANOVA. The results showed that the red coconut embryo extract had a significant effect on reducing blood glucose levels in alloxan-induced mice. The most effective concentration was 40% (PI), with an average blood glucose level of 98.6 mg/dL.
Co-Authors Achmad Ramadhan Manap Trianto Masriani . Novi, Winda Cinthia Sutrisnawati Mardin