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All Journal JOURNAL LA MEDIHEALTICO Innovative: Journal Of Social Science Research
Iswahyudi, Andi Alfiyah Az-Zahro
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Humanities Computer Science & IT Health Professions Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Nursing Public Health Veterinary Other

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Pengaruh Aktivitas Fisik Terhadap Kejadian Gagal Jantung Kongestif Di RS Ibnu Sina Makassar Tahun 2022 Iswahyudi, Andi Alfiyah Az-Zahro; Wisudawan, Wisudawan; Darma, Sidrah; Nurhikmahwati, Nurhikmahwati; Nurmadilla, Nesyana
Innovative: Journal Of Social Science Research Vol. 4 No. 1 (2024): Innovative: Journal Of Social Science Research
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/innovative.v4i1.8909

Abstract

Latar Belakang: Gagal Jantung Kongestif adalah kumpulan gejala kompleks akibat adanya gangguan pada proses kerja jantung, baik secara struktural maupun fungsional. Upaya untuk meningkatkan kapasitas fungsional dengan melakukan latihan fisik. Tujuan: Mengetahui pengaruh aktivitas fisik terhadap kejadian gagal jantung kongestif di RS Ibnu Sina Makassar tahun 2022. Metode: Penelitian ini menggunakan desain penelitian observasional dengan  pendekatan cohort retrospektif berdasarkan data primer melalui wawancara dengan kuesioner terstruktur IPAQ (International Physical Activity Questionnare). Hasil: Di dapatkan 28 pasien terdiagnosis gagal jantung kongestif sebanyak 16 orang berjenis kelamin laki-laki (57.1%), mayoritas pada kelompok usia 55-65 tahun sebanyak 13 orang (46.4%), 14 orang melakukan aktivitas fisik sedang (50%), 13 orang melakukan aktivitas fisik rendah (46.4%) dan 1 orang melakukan aktivitas fisik berat (3.6%) dan terdapat hubungan bermakna antara hubungan usia dengan aktivitas fisik dengan nilai p-value 0.031 (p-value < 0.05). Di dapatkan 28 pasien terdiagnosis gagal jantung kongestif berdasarkan klasifikasi NYHA dimana mayoritas berada pada kelas 2 dengan jumlah 24 orang (85,7%) dan 4 orang berada pada kelas 1 (14.3%). 28 pasien terdiagnosis Gagal Jantung Kongestif berdasarkan berdasarkan aktivitas fisik, dimana sebanyak 24 orang berada pada NYHA kelas 2. Sebanyak 11 orang melakukan aktivitas fisik rendah (45.8%), 12 orang melakukan aktivitas fisik sedang (50%) dan 1 orang melakukan aktivitas fisik berat (4.2%). Berdasarkan hasil perhitungan Chi-square diperoleh p-value = 0.914 < α = 0,05 (nilai p-value lebih besar dari α = 0,05). Hal ini berarti terdapat hubungan yang signifikan antara Hubungan Jenis Kelamin Pasien Jantung Kongestif dengan Aktivitas Fisik yang dilakukan pasien Gagal Jantung Kongestif di RS Ibnu Sina Makassar. Kesimpulan: Pasien terdiagnosis gagal jantung kongestif dari 28 pasien mayoritas berjenis kelamin laki-laki, kelompok usia 55-65 tahun dan berdasarkan tingkat aktivitas fisik paling banyak melakukan aktivitas fisik sedang.
Effectiveness of Angiotensin Converting Enzyme Inhibitors and Beta-Blockers in Reducing Mortality in Patients with Congestive Heart Failure Iswahyudi, Andi Alfiyah Az-Zahro; Wisudawan; Ardiyanto
Journal La Medihealtico Vol. 7 No. 2 (2026): Journal La Medihealtico
Publisher : Newinera Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37899/journallamedihealtico.v7i2.3218

Abstract

CHF is a chronic and progressive cardiovascular disease with high morbidity, frequent hospitalization and a high mortality rate, especially for individuals with HFREF. The purpose of this study is to assess the efficacy of angiotensin converting enzyme inhibitors and beta blockers in the reduction of mortality in congestive heart failure patients especially in terms of the neurohormonal modulation and long-term clinical results. In this study, a narrative literature review design was used to obtain secondary data from national and international journals, textbooks, ClinicalKey, ScienceDirect, PubMed, Google Scholar, scientific websites of publishers, and other relevant scientific sources. The existing literature focused on studies from 2015 to 2026, with the exception of landmark studies from the past that provided foundational evidence relevant to heart failure pharmacotherapy. The results suggest that ACE inhibitors and beta blockers are associated with consistently lower mortality, hospitalization rate and clinical stability, particularly in those with heart failure with reduced EF. Angiotensin converting enzyme inhibitors (ACE inhibitors) can help decrease the harmful effects of activation of the renin angiotensin aldosterone system (RAAS) while beta blockers can help to reduce excessive sympathetic nervous system activity. They both have complementary neurohormonal control and can have a wider clinical effect than monotherapy, if used appropriately. The therapeutic efficacy, however, is not consistent in every patient, and may be affected by the level of ejection fraction (EF), age, comorbidities, disease severity, drug tolerance, dose optimization, and adherence to therapy. This review demonstrates that ACE inhibitors and beta blockers are still employed by patients with CHF and are still considered critical components of guideline directed pharmacologic therapy, especially in those patients with reduced EF.
Co-Authors Ardiyanto Darma, Sidrah Nurhikmahwati, Nurhikmahwati Nurmadilla, Nesyana Wisudawan Wisudawan, Wisudawan