Lidya Pratiwi Afri Tjaja
Department Of Clinical And Community Pharmacy, STIKes Widya Dharma Husada, Tangerang Selatan

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Pengaruh Kualitas Pelayanan, Harga dan Brand Image dengan Minat Beli Terhadap Keputusan Pembelian Produk Obat OTC di Apotek X Jakarta Timur Tjaja, Lidya Pratiwi Afri; Yantih, Novi; Hatta, Iha Haryani
MAHESA : Malahayati Health Student Journal Vol 3, No 12 (2023): Volume 3 Nomor 12 (2023)
Publisher : Universitas Malahayati

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33024/mahesa.v3i12.12004

Abstract

ABSTRACT The increasingly fierce competition in the pharmaceutical business has forced pharmacies to develop strategies so that more consumers are interested in buying and purchasing OTC medicine products. East Jakarta Pharmacy X's strategy to influence consumer purchasing decision on OTC medicine products using service quality, price and brand image. The purpose of this study focuses on knowing the direct and indirect effect of service quality, price, and brand image with purchase intention on purchasing decisions OTC medicine products at pharmacy X in East Jakarta. The research sample was 200 respondents who were consumers who had purchased OTC medicine products at pharmacy X in East Jakarta at least twice. The sampling technique is purposive sampling. The data analysis technique used Partial Least Square (PLS) Structural Equation Modeling (SEM) analysis which was processed with the help of Smart PLS 3.0 software. The results of the study prove that the service quality, price, and brand image variable directly has a positive and significant effect on purchasing decisions. The price variable directly has a positive and significant effect on purchasing decisions. The service quality, price, and brand image variable has a positive and significant effect on purchasing decisions with purchase intention. Keywords: Service Quality, Price, Brand image, Purchase Intention, Purchase Decision ABSTRAK Persaingan bisnis farmasi yang semakin ketat membuat apotek merancang strategi agar lebih banyak konsumen berminat membeli dan melakukan pembelian produk obat OTC di Apotek X Jakarta Timur. Strategi apotek X Jakarta Timur untuk mempengaruhi keputusan pembelian konsumen pada produk obat OTC menggunakan kualitas pelayanan, harga dan citra merek. Tujuan penelitian ini berfokus untuk mengetahui pengaruh kualitas pelayanan, harga, dan citra merek dengan minat beli terhadap keputusan pembelian produk obat OTC di Apotek X Jakarta Timur. Sampel penelitian sejumlah 200 responden yang merupakan konsumen yang pernah membeli produk obat OTC di Apotek X Jakarta Timur minimal dua kali. Teknik pengambilan sampel yaitu purposive sampling. Teknik analisis data menggunakan analisis Structural Equation Modeling (SEM) Partial Least Square (PLS) yang diolah dengan bantuan software Smart PLS 3.0. Kesimpulan penelitian ini membuktikan bahwa variabel kualitas pelayanan, harga, dan citra merek berpengaruh positif dan signifikan terhadap keputusan pembelian. Variabel kualitas pelayanan berpengaruh positif dan signifikan terhadap keputusan pembelian dengan minat beli. Variabel harga berpengaruh positif dan signifikan terhadap keputusan pembelian dengan minat beli. Variabel citra merek berpengaruh positif dan signifikan terhadap keputusan pembelian dengan minat beli. Kata Kunci: Kualitas Pelayanan, Harga, Citra Merek, Minat Beli, Keputusan Pembelian
In-Silico Study and Antioxidant Capacity from Jamaican Cherry, Red Ginger, Thyme Combination as Multi-target Nutraceutical for Chronic Obstructive Pulmonary Disease Sayyidah Sayyidah; Nenden Nurhasanah; Lidya Pratiwi Afri Tjaja; Nanang Yunarto
Jurnal Kefarmasian Indonesia VOLUME 16, NUMBER 1, JUNE 2026
Publisher : Pusat Penelitian dan Pengembangan Biomedis dan Teknologi Dasar Kesehatan

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Abstract

Chronic obstructive pulmonary disease (COPD) is one of the health concerns in Indonesia with 4.8 million people suffer from COPD. Global Adult Tobacco Survey Indonesia reported 70.2 million active smokers in 2021. This trend raises concerns about the future trajectory of COPD cases in the country. COPD is a chronic condition that impairs the lower respiratory system due to progressive stimuli that initiate oxidant-antioxidant imbalance contributes to dysregulated inflammation cascade response. Some natural ancient plants that had been used to relieve respiratory discomfort are Ginger (Zingiber officinale var.Rubrum) and Thyme (Thymus vulgaris). In order to give synergetic mechanism to imboost antioxidant capacity also mitigate COPD symptoms, this research combine both plants with Jamaican Cherry (Muntingia calabura) leave as a powder drink formulation. This study is conducted to analysis the potential of these combination through in-silico along with antioxidant capacity evaluation from each formulation.  Total 75 compounds that meet Lipinski rules from the plants had been screened to identify the overlapping genes. Based on Network Pharmacology and validated with molecular docking analysis the potential targets based on the best degree value were IL-8(-11.2 kcal/mol), TNF-α (-8.9 kcal/mol), MMP-9(-7.7 kcal/mol) and IL-6(-7 kcal/mol). The highest binding affinity compound was 3’-hydroxydaidzein from Jamaican Cherry. The powder drink formulation made through wet granulation and antioxidant evaluated using DPPH(1,1-diphenyl-2-picrylhydrazyl) method. The antioxidant capacity was IC50 39.99 ppm; 36.10 ppm ; and 28.30 ppm for F1, F2 and F3 respectively compared to ascorbic acid 13.03 ppm. To conclude, this natural combination nutraceutical has potential as supportive natural remedy for COPD.