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Putra, Wayan
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Biochemistry, Genetics & Molecular Biology Education Health Professions Immunology & microbiology Medicine & Pharmacology Public Health Other

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Recurrent Pneumothorax in a Patient with Post-Tuberculosis Sequelae: A Case Report Brama, Bagus; Putra, Wayan
Malang Respiratory Journal Vol. 6 No. 1 (2024): March 2024 Edition
Publisher : Universitaas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.mrj.2024.006.01.02

Abstract

Introduction: Tuberculosis and its complications could lead to a condition with a high mortality and morbidity in which those complications include hemoptysis, pleural effusions, post tubercular lung disease and spontaneous pneumothorax. Pneumothorax in one possible complication in pulmonary tuberculosis with an incidence rate up to 1.5%. Case: A 46 years old man came to emergency room due to shortness of breath that had been felt since one week before and worsened after lifting some weight things 30 minutes prior the admission, the shortness of breath was described as heavy sensation whenever patient breaths, this complaint was accompanied by pain in the right lung, he has a history of lung tuberculosis and had completed his treatment, radiology examination showed right pneumothorax and later patient was hospitalized for a week with Water Seal Drainage (WSD) placed in his right lung. One month later, patient came back to emergency room with the same symptoms and was hospitalized again, but this time, pleurodesis was done. Discussion: Tuberculosis causes damage to lung structure, and disturb its function leaving a sequelae and causing disability called post-tuberculosis lung disease (PTLD). Secondary spontaneous pneumothorax is pneumothorax that occurring in a setting of underlying lung disease. Patients with SSP tolerate pneumothorax less well and display heavier symptoms, even if the pneumothorax is relatively small in size. Conclusions: The inflammation and fibrosis process on Tuberculosis infection leaves a sequelae damage and increased the vulnerability of someone lung’s that could lead to many complications such as pneumothorax. Key words: Pneumothorax, Post-Tuberculosis Sequelae, Recurrent.
A Very Rare Case of Pulmonary Lepidic Adenocarcinoma at a Young Age Man Kristy, Anastasia; Putra, Wayan
Malang Respiratory Journal Vol. 6 No. 2 (2024): September 2024
Publisher : Universitaas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.mrj.2024.006.02.06

Abstract

Introduction: Lung cancer remains one of the higher prevalence of cancer and leading cause of death in the world. Smoking and genetic factors are two important etiologies in lung cancer. Adenocarcinoma is the most common type of non-small cell lung carcinoma. Lepidic predominant adenocarcinoma is one type of adenocarcinoma that has a good prognosis. Case Illustration: A 24-year-old male came with chronic cough and chest pain. He had a history of smoking and no prior family history of cancer. Plain chest Xray and Thorax computed tomography (CT) showed pleural effusion and presence of lung mass with suggestion of bone and liver involvement, respectively. The cytology from pleural effusion and bronchial lavage initially found no malignancy cell. Later thoracostomy biopsy and pathology study suggested lepidic adenocarcinoma. Discussion: Lung cancer is still one of the leading causes of death in men. Even though rarely found in young male, patients with a history of smoking or genetic factor with clinical manifestation suggestive chronic respiratory condition with weight loss should be suspected of the diagnosis. Adenocarcinoma, as the most common non-small cell lung carcinoma, could be later divided into several subtypes. Lepidic adenocarcinoma is distinguished by the pathology finding of a large invasion focus of stromal, lymphatic, vascular, or pleural space. Considered one of the most favorable, lepidic predominant adenocarcinoma has a very high rate of 5 year survival when diagnosed early and responds well to lobe resection. Advanced state however has poor outcome due to limited choice of therapy. Promising trial of targeted chemotherapy have been reported and could improve outcome in the future. Conclusion: Lung cancer in young male is a rare disease but should be suspected in those with chronic cough, chest pain and weight loss. The history of smoking and family history are crucial for this suspicion. Lepidic predominant adenocarcinoma has a good prognosis when diagnosed early. Studies in the future could enhance overall survival in these patients.
Co-Authors Brama, Bagus Kristy, Anastasia