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All Journal Jurnal Respirasi (JR) Jurnal Prima Medika Sains Malang Respiratory Journal
Kristy, Anastasia
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Biochemistry, Genetics & Molecular Biology Education Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health Other

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Efektivitas sabun antiseptik dalam menghambat pertumbuhan Escherichia coli dan Salmonella typhi Kristy, Anastasia; Lubis, Adhayani; Rahimi, Armon; Alexander, Rico; -, Janice; Rosari, Anita; Kotsasi, Fransiska; Pardianto, Gede
Jurnal Prima Medika Sains Vol. 3 No. 1 (2021): Juni
Publisher : Program Studi Magister Kesehatan Masyarakat Universitas Prima Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34012/jpms.v3i1.1788

Abstract

Tujuan dari penelitian ini adalah untuk menguji daya hambat sabun antiseptik dalam menghambat pertumbuhan bakteri Escherichia coli dan Salmonella typhi. Sampel yang dipakai adalah sebanyak 4 sabun antiseptik (sabun A, B, C dan D) dengan masing-masing konsentrasi sebesar 10%, 20%, 30% dan 40%. Proses pengenceran sesuai dengan konsentrasinya dapat mengubah kemampuan sabun dalam menghambat pertumbuhan bakteri yang diuji dengan metode difusi. Hasil penelitian didapatkan bahwa keempat sampel sabun antiseptik memiliki efektivitas antibakteri terhadap Escherichia coli dan Salmonella typhi. Namun pada Escherichia coli, rata-rata diameter zona hambat yang paling besar adalah pada sabun antiseptik A dengan konsentrasi 40% yaitu 26 mm dan rata-rata diameter zona hambat paling kecil adalah pada sabun antiseptik D dengan konsenstrasi 10% yaitu 7 mm. Sedangkan pada Salmonella typhi rata-rata diameter zona hambat paling besar adalah pada sabun antiseptik A dengan konsentrasi 40% yaitu 20 mm dan rata-rata diameter zona hambat paling kecil adalah pada sabun antiseptik B dengan konsentrasi 10% yaitu 10 mm. Hal tersebut dapat terjadi karena dinding penyusun dari kedua bakteri tersebut berbeda dan kandungan dari masing-masing sabun juga berbeda.
Diagnostic challenge of Pneumocystis jirovecii pneumonia infection mimicking interstitial lung disease in initially HIV negative patient Kristy, Anastasia; Yaniswari, Ni Made Dwita
Jurnal Prima Medika Sains Vol. 5 No. 2 (2023): December
Publisher : Program Studi Magister Kesehatan Masyarakat Universitas Prima Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34012/jpms.v5i2.4455

Abstract

Background: Pneumocystis jirovecii pneumonia (PJP) infections are common in immunocompromised patients and are rarely found in immunocompetent patients. Lung radiology in PJP patients could mimic the appearance of interstitial lung disease (ILD) and could be used to diagnose HIV-negative patients. Clinicians should rule out false negatives in patients with patterns suggestive of opportunistic infections and risk factors for HIV infection. Case illustration: A 34-year-old man presented with a chief complaint of shortness of breath, had history of 15 years of smoking, and daily chlorine exposure. The radiology pattern and initial HIV-negative test results suggested an ILD diagnosis. Owing to persistent symptoms despite initial management and the presence of risk factors, repeat HIV testing was initiated and was positive. The patient was treated with cotrimoxazole and showed rapid clinical improvement. Discussion: The diagnosis of PJP in our patient was based on radiology and an HIV-positive status.  In patients who are not immunocompromised, the diagnosis of PJP is unlikely, and other diagnoses, such as ILD, should be considered. However, in the HIV testing window period of infection, a poor advanced state of HIV could cause a false negative result. Therefore, clinical judgement is essential in suspecting such a result. The empirical treatment course of cotrimoxazole has been shown to provide better clinical outcomes in PJP. Conclusion: The possibility of PJP must be considered in patients with initially HIV-negative results, especially in patients with risk factors and clinical symptoms suggestive of immunocompromise. While some ILD showed similar PJP, the risk factors for ILD and PCP could be distinguishing factors. Retesting for HIV infection can confirm the diagnosis and rule out false-negative results.
The role of air purifier in reducing indoor airborne particulate matter to improve respiratory health Kristy, Anastasia; Putra, Wayan Wahyu Semara
Jurnal Prima Medika Sains Vol. 6 No. 2 (2024): December
Publisher : Program Studi Magister Kesehatan Masyarakat Universitas Prima Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34012/jpms.v6i2.6144

Abstract

Introduction: The recent surge in respiratory diseases has heightened concerns about air quality, particularly for individuals who spend most of their time indoors. Air purifiers, alongside good ventilation and self-protection are now among the preferred methods for ensuring clean and breathable air. Discussion: Reducing the levels of airborne pollutants is crucial for maintaining respiratory health, reducing the incidence of respiratory diseases, and preserving pulmonary function. Particulate matter (PM) serves as a key indicator of air quality. Conclusion: Air purifiers, such as those with High-Efficiency Particulate Air (HEPA) filters, are closely linked to improved air quality by effectively reducing particulate matter (PM), thereby offering long-term health benefits.
The Role of Macronutrients in Chronic Obstructive Pulmonary Disease: A Review Kristy, Anastasia; Hardian, Harris; Putra, Wayan Wahyu Semara; Yaniswari, Ni Made Dwita; Tania, Tryna
Jurnal Respirasi Vol. 10 No. 2 (2024): May 2024
Publisher : Faculty of Medicine Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jr.v10-I.2.2024.161-167

Abstract

The incidence of chronic obstructive pulmonary disease (COPD) is rising and is still regarded as one of the challenging medical issues. Regardless of the main relationship between tobacco smoking and toxic particle exposure with COPD, factors like nutritional status also play an important role in COPD progression and outcome, as the factor is an adaptable aspect. Malnutrition, sarcopenia, and obesity are nutritional problems that are often encountered in COPD patients. Macronutrients, namely carbohydrates, fat, and protein, support the adjunctive treatment options for COPD. The ideal dietary pattern includes low carbohydrates, medium fats preferably polyunsaturated fatty acids (PUFA), and high proteins to improve COPD symptoms, preserve muscle mass, and delay disease progression. High carbohydrate intake might also increase the respiratory quotient (RQ) which results in higher carbon dioxide (CO2) production and oxygen (O2) demand compared to fat and protein intake. Daily calorie intake should be adjusted to personal nutritional status. Higher calories in malnourished, sarcopenic patients and targeted weight loss in obese patients show improvements in lung function, frequency of exacerbations, and hospitalization rate. In obese individuals with COPD, however, maintaining a slightly higher body mass index (BMI) of 25-30 kg/m2 was associated with lower mortality. This literature review summarized the significant role of macronutrients in COPD patients and the practical approach to macronutrient intervention in individuals with different nutritional statuses.
A Very Rare Case of Pulmonary Lepidic Adenocarcinoma at a Young Age Man Kristy, Anastasia; Putra, Wayan
Malang Respiratory Journal Vol. 6 No. 2 (2024): September 2024
Publisher : Universitaas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.mrj.2024.006.02.06

Abstract

Introduction: Lung cancer remains one of the higher prevalence of cancer and leading cause of death in the world. Smoking and genetic factors are two important etiologies in lung cancer. Adenocarcinoma is the most common type of non-small cell lung carcinoma. Lepidic predominant adenocarcinoma is one type of adenocarcinoma that has a good prognosis. Case Illustration: A 24-year-old male came with chronic cough and chest pain. He had a history of smoking and no prior family history of cancer. Plain chest Xray and Thorax computed tomography (CT) showed pleural effusion and presence of lung mass with suggestion of bone and liver involvement, respectively. The cytology from pleural effusion and bronchial lavage initially found no malignancy cell. Later thoracostomy biopsy and pathology study suggested lepidic adenocarcinoma. Discussion: Lung cancer is still one of the leading causes of death in men. Even though rarely found in young male, patients with a history of smoking or genetic factor with clinical manifestation suggestive chronic respiratory condition with weight loss should be suspected of the diagnosis. Adenocarcinoma, as the most common non-small cell lung carcinoma, could be later divided into several subtypes. Lepidic adenocarcinoma is distinguished by the pathology finding of a large invasion focus of stromal, lymphatic, vascular, or pleural space. Considered one of the most favorable, lepidic predominant adenocarcinoma has a very high rate of 5 year survival when diagnosed early and responds well to lobe resection. Advanced state however has poor outcome due to limited choice of therapy. Promising trial of targeted chemotherapy have been reported and could improve outcome in the future. Conclusion: Lung cancer in young male is a rare disease but should be suspected in those with chronic cough, chest pain and weight loss. The history of smoking and family history are crucial for this suspicion. Lepidic predominant adenocarcinoma has a good prognosis when diagnosed early. Studies in the future could enhance overall survival in these patients.
Co-Authors -, Janice Alexander, Rico Hardian, Harris Kotsasi, Fransiska Lubis, Adhayani Pardianto, Gede Putra, Wayan Putra, Wayan Wahyu Semara Rahimi, Armon Rosari, Anita Tania, Tryna Yaniswari, Ni Made Dwita