Article Per Year (5 Year)
p-Index From 2020 - 2025
0.23
P-Index
This Author published in this journals
All Journal Journal of Pharmaceutical and Sciences.
Jumardi, Muhammad Ikhsan
Unknown Affiliation
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Nursing Public Health

Published : 1 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 1 Documents
Search

 1 
Uji toksisitas buah palem merah (Cyrtostachys renda Blume.) menggunakan metode brine shrimp lethality test (BSLT) method Syamsurizal, Syamsurizal; Utami, Diah Tri; Sutrisno, Sutrisno; Efrini, Emi; Jumardi, Muhammad Ikhsan
Journal of Pharmaceutical and Sciences Suppl. 1, No. 1 (2023)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v6i5-si.429

Abstract

The red palm plant (Cyrtostachys renda) is a species of the Areca genus that grows widely in Jambi Province, making it an affordable plant to research for its medicinal properties. The Brine Shrimp Lethality Test (BSLT) is a toxicity test to screen for anticancer bioactive substances, with the test subject being Artemia salina Leach larvae, which are highly sensitive when exposed to toxic substances. The fruit and roots of C. renda were extracted using the maceration method by using a methanol solvent and partitioning using n-hexane, dichloromethane, ethyl acetate, and water. Based on the extract toxicity evaluation results, all extracts were toxic. Meanwhile, C.renda root dichloromethane extract had the highest toxic properties, with an LC50 value of 43.42 ± 0.659 ppm. However, the positive control's toxicity, potassium dichromate, was more toxic, with an LC50 value of 29.93 ± 0.668 ppm. The dichloromethane extract of C. renda roots can potentially be a poisonous agent. Further toxicity tests on cancer cells need to be carried out to be developed as an anticancer agent.
Co-Authors Efrini, Emi Sutrisno, Sutrisno Syamsurizal - - Utami, Diah Tri