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All Journal Jurnal Mahasiswa Jurusan Teknik Pengairan Jurnal Aisyah : Jurnal Ilmu Kesehatan SCIENCE : Jurnal Inovasi Pendidikan Matematika dan IPA Pharmaceutical Sciences and Research (PSR) Elementary School: Jurnal Pendidikan dan Pembelajaran ke-SD-an JOURNAL OF CHEMICAL NATURAL RESOURCES (JCNaR) Jurnal Karya Abdi Masyarakat Journal of Pharmaceutical and Sciences.
Utami, Diah Tri
Unknown Affiliation
Religion Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Civil Engineering, Building, Construction & Architecture Computer Science & IT Economics, Econometrics & Finance Education Health Professions Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Nursing Public Health Veterinary

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KAJIAN DISTRIBUSI KECEPATAN ALIRAN DIPERCEPAT PADA SALURAN TERBUKA LURUS Utami, Diah Tri; Dermawan, Very; Sumiadi, Sumiadi
Jurnal Mahasiswa Jurusan Teknik Pengairan Vol 2, No 2 (2019)
Publisher : Jurusan Teknik Pengairan, Fakultas Teknik, Universitas Brawijaya

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Abstract

ABSTRAK: Pada aliran tidak seragam pembagian distribusi kecepatan aliranya tidak merata pada setiap section atau titik pengamatan. Penelitian ini dilakukan pada saluran terbuka lurus dengan dasar tetap (fix bed), saluran terbuat dari acrylic dengan panjang 900 cm dan lebar 7,6 cm dan tinggi 25 cm. Kemiringan dasar saluran menggunakan sistem terjunan (adverse slope) dengan kemiringan -0,0171 agar tercipata aliran dipercepat dengan beda tingi muka air yang signifikan. Penelitian ini menggunakan 3 variasi debit yaitu Q1 3,95 lt/dt, Q2 2,38 lt/dt, dan Q3 1,12 lt/dt. Pengamatan kecepatan dilakukan pada 5 section pengukuran dengan jarak 10cm dari ujung terjunan, 20 cm, 50 cm, 50 cm, 50 cm menuju ke hulu saluran. Dari hasil pengamatan dan pengukuran aliran pada saluran adalah aliran subkritis dengan nilai Fr<1 sehingga pengukuran dilakukan dari hilir ke hulu. Pada pengukuran ketinggian muka air diketahui bahwa ketinggian muka air semkin berkurang dari hulu menuju ke hilir, dan dari pengukuran kecepatan dengan menggunakan tabung pitot menunjukan peningkatan kecepatan dari hulu ke hilir saluran. Pengukuran kecepatan aliran secara teoritis dihitung dengan menggunakan metode Logaritmik dan Von karman. Hasil perhitungan kecepatan secara teoritis mendekati hasil pengukuran kecepatan dengan menggunakan tabung pitot pada daerah inner region dan semakin menjauh pada daerah outer region pada semua section pengukuran. Kecepatan geser dasar dihitug dengan menggunakan metode Clauser, dan didapatkan nilai tegangan geser dasar yang semakin ke hilir nilainya semakin besar. Kata Kunci: Distribusi kecepatan, aliran dipercepat, aliran tidak seragam, saluran terbuka ABSTACT: Velocity distribution in non-uniform flow is not evenly distributed in each point of observation. This study was conducted on a straight open channel with a fixed bed, made of acrylic with a length of 900 cm, width of 7.6 cm and a height of 25 cm. The channel bed is made with a drop structure (adverse slope) with a slope of -0.0171 so that the flow rate is accelerated with a significant difference in water level. This study uses 3 variations of discharge, such as Q1 3.95 l/s, Q2 2.38 l/s, and Q3 1.12 l/s. Velocity ​observation was carried out on 5 sections of measurement with a distance of 10cm from the end of drop structure, 20 cm, 50 cm, 50 cm, 50 cm towards the upstream channel. From the results of observations and measurements, the flow on the channel is subcritical flow with a value of Fr <1 so that measurements were done from downstream to upstream. On water level measurements it is known that the water level may decrease from upstream to downstream, and from velocity measurements using pitot tubes shows an increase in speed from upstream to downstream of the channel. The measurement of flow velocity is theoretically calculated using the Logarithmic and Von Karman methods. The results of velocity calculations theoretically approach the results of velocity measurements by using pitot tubes in the inner region and getting farther away in the outer region in all measurement sections. The bed shear velocity was calculated using the Clauser method, and the value of the bed shear stress was getting higher as the flow reached the downstream. Keywords: velocity distribution, accelerated flow, non-uniform flow, open-channel
Development of Ethanolic Extract of Pinang Masak Jambi (Areca Catechu L.) as A Modulator of Doxorubicin Cytotoxic Effect in Breast Cancer Therapy Fitrianingsih, Fitrianingsih; Maharini, Indri; Utami, Diah Tri
Pharmaceutical Sciences and Research Vol. 7, No. 1
Publisher : UI Scholars Hub

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Abstract

Doxorubicin is one of the chemotherapy agents that is often used in breast cancer therapy. Phenomenon of breast cancer cell resistance to chemotherapy agents has been traced to the molecular level. The development of compounds that can overcome drug resistance chemotherapy needs to be continuously developed, especially agents with specific molecular targets, namely P-glycoprotein (Pgp), NFkB, cyclin, and cyclin-dependent kinase (CDK). Another alternative is the combination of chemotherapy agents with chemopreventive agents (co-chemotherapy) to reduce side effects and increase sensitivity of cancer cells. Doxorubicin is often used in breast cancer therapy. This study was performed to determine the effect of ethanolic extract of Pinang Masak Jambi (Areca catechu L.) (EEPMJ) and doxorubicin combination on MCF-7 breast cancer cells. Cytotoxic assay of EEPMJ and doxorubicin, alone, or in combination, was done using MTT test method to determine the IC50 and CI (Combination Index) values. The results indicated that EEPMJ and doxorubicin had IC50 values of 75.1 µg/ml and 22 µg/ml, respectively. Based on CI values, all combination concentration showed varying CI values. The concentration of 1/8 IC50 of EEPMJ with 1/2, 1/4, and 1/8 IC50 of doxorubicin showed a strong synergistic effect (CI 0.1 - 0.3), with the inhibition of cell viability up to 67.39%. This synergistic effect occurs because EEPMJ potentially could increases the cytotoxicity of doxorubicin.
PEMBERDAYAAN MASYARAKAT DALAM SWAMEDIKASI PENYAKIT RADANG SENDI DI DESA MENDALO INDAH KECAMATAN JAMBI LUAR KOTA ., Elisma; Maharini, Indri; ., Fitrianingsih; Utami, Diah Tri
Jurnal Karya Abdi Masyarakat Vol. 1 No. 1 (2017): Jurnal Karya Abdi Masyarakat
Publisher : LPPM Universitas Jambi

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (240.611 KB) | DOI: 10.22437/jkam.v1i1.3766

Abstract

Penyakit radang sendi atau sering dikenal dengan istilah rematik merupakan penyakit yang banyak menyerang masyarakat pada usia 25-74 tahun dengan prevalensi dan keparahan yang meningkat dengan usia. Terapi pada penyakit ini bukan hanya dengan pemberian obat tapi juga ditunjang oleh terapi non obat. Pemanfaatan tanaman yang bekhasiat sebagai obat tradisional juga dapat menunjang terapi ini, mengingat pengobatan rematik membutuhkan waktu yang sangat lama, bahkan selama hidup. Hal ini dapat menimbulkan resiko efek samping obat yang dikonsumsi. Dengan demikian diperlukan berbagai terapi non obat serta pengobatan alternatif untuk menunjang penatalaksanaan dari penyakit ini. Program ini akan dilaksanakan di Desa Mendalo Indah, RT 02 Kec. Jambi Luar Kota dengan tujuan memberikan pengetahuan dan keterampilan kepada masyarakat dalam mengatasi penyakit radang sendi (rematik) baik dengan terapi menggunakan obat, obat alternatif maupun dengan terapi non obat seperti diet makanan dan melakukan latihan fisik tertentu agar ketidakberdayaan (disability) yang diakibatkan penyakit ini dapat diatasi sehingga kualitas hidup masyarakat menjadi meningkat dengan mengetahui cara pengobatan yang efektif. Hasil evaluasi pelaksanaan pengabdian yang diikuti oleh warga RT 02, desa Mendalo Indah adalah warga memahami tentang penyakit radang sendi dan bagaimana penatalaksanaannya baik secara farmakogis maupun non farmakologis sehingga mampu melakukan swamedikasi terhadap penyakit itu sendiri untuk menciptakan masyarakat yang peduli dengan kesehatan guna mewujudkan Indonesia sehat. Disamping itu juga diperoleh gambaran insidensi penyakit radang sendi khususnya asam urat pada masyarakat di desa Mendalo Indah.
Pengembangan Flipbook Digital Berbasis Problem Based Learning Untuk Meningkatkan Hasil Belajar Kelas V Utami, Diah Tri; Ansori, Isa
Elementary School: Jurnal Pendidikan dan Pembelajaran ke-SD-an Vol. 12 No. 2 (2025): ELEMENTARY SCHOOL (Jurnal Pendidikan dan Pembelajaran Ke-SD-an)
Publisher : Universitas PGRI Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31316/esjurnal.v12i2.4481

Abstract

Penelitian ini bertujuan untuk mengembangkan media Flipbook Digital berbasis model Problem Based Learning untuk meningkatkan hasil belajar siswa kelas V. Penelitian ini merupakan penelitian Research and Development (R&D), dengan model pengembangan ADDIE (Analysis, Design, Development, Implementation, and Evaluation). Media Flipbook Digital berbasis Problem Based Learning yang dikembangkan memperoleh kelayakan oleh ahli media dengan skor 92,17% dan ahli materi serta bahasa dengan skor 98,40%. Hasil angket respons guru sebesar 98% dan respons siswa sebesar 90,33% dengan kriteria “Sangat Valid”. Keefektifan media Flipbook Digital dilihat dari hasil uji Paired Sample T-Test dan uji N-Gain. Hasil uji Paired Sample T-Test pada skala kecil dan skala besar menunjukkan nilai 0,00. Sedangkan hasil uji N-Gain pada skala kecil menunjukkan nilai 0,80 dan pada skala besar menunjukkan nilai 0,76 yang keduanya termasuk dalam kategori “Tinggi”. Jadi, media Flipbook Digital berbasis Problem Based Learning yang dikembangkan dinyatakan layak dan efektif untuk meningkatkan hasil belajar siswa.
Formulasi produk diswashing liquid berbasis minyak atsirih sereh wangi sebagai anti bakteri Halim, Rd; Utami, Diah Tri; Lesmana, Oka
Jurnal Aisyah : Jurnal Ilmu Kesehatan Vol 8, No 4: Desember 2023
Publisher : Universitas Aisyah Pringsewu

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30604/jika.v8i4.2071

Abstract

Minyak atsiri serai dalam sediaan sabun cuci piring dapat berfungsi sebagai antibakteri, meningkatkan efektivitas sabun dalam fungsinya sebagai pembersih kulit. Penelitian bertujuan  membuat formulasi diswashing liquid serai wangi dan pengujian mutu yaitu homogenitas, organoleptik, pH, stabilitas busa, viskositas. dan aktivitas anti bakteri. Jenis penelitian ini merupakan penelitian eksperimen dengan menggunakan rancangan acak lengkap, (RAL) terdiri dari satu faktor dan tiga kali pengulangan. Sampel dalam penelitian ini adalah minyak sereh wangi hasil penyulingan uap  pada formulasi Diswashing Liquid anti bakteri Staphylococcus Aureus. Parameter yang diukur adalah homogenitas, PH, viskositas, organoleptik, stabilitas busa dan daya hambatt bakteri. Analisis data dilakukan secara deskriptif, disajikan dalam bentuk tabel dan grafik. Hasil penelitian formulasi adalah F0 : 0%, F1: 1%, F2: 1.5%, F3: 2%. F4 : 3% Uji organoleptik diperoleh hasil sabun dengan bau khas serai, warnanya oren transfaran, berbentuk acairan kental. Uji homogenitas semua formulasi homogen. Hasil uji pH rata rata : 9. Hasil uji tinggi dan kestabilan busa berkisar antara 83,12%, - 92,50 %, hasil uji viskositas berkisar antara 6.140–54.305. Daya hambat bakteri: 0,03 – 8,33 mm. Formulasi Diswashing Liquid serai wangi sudah memenuhi standar SNI
STRATEGI MENINGKATKAN PEMAHAMAN VISUALISASI SISWA MELALUI BUKU POP-UP SERI ANATOMI DAN FISIOLOGI MANUSIA Yuliawati, Yuliawati; Utami, Diah Tri; Elisma, Elisma
SCIENCE : Jurnal Inovasi Pendidikan Matematika dan IPA Vol. 5 No. 1 (2025)
Publisher : Pusat Pengembangan Pendidikan dan Penelitian Indonesia (P4I)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51878/science.v5i1.4505

Abstract

The attainment of learning competencies is contingent on the quality of the offered material and the utilized learning media. Pop-up books function as captivating instructional instruments, incorporating three-dimensional elements that facilitate movement and enrich the visuals on each page. Human Anatomy and Physiology courses constitute a vital element of health education and typically necessitate appealing graphic illustrations. This study seeks to examine the impact of pop-up books on student comprehension. This research design employs a pure experimental methodology with a one-group pretest-posttest framework. The research sample comprised students from the Pharmacy Study Program at the Faculty of Medicine and Health Sciences, Jambi University, for the academic year 2020/2021. The investigated data consists of test results obtained before and after utilizing the pop-up book. The aggregate of all scores divided by the student count yields the class average. This average value determines the overall capability of the class. Subsequently, ascertain the number of students who have not met the learning success target and the percentage of those who have attained it. The research findings indicate that pop-up book media can effectively enhance student performance in Human Anatomy and Physiology courses. ABSTRAKKetercapaian kompetensi pembelajaran tidak hanya bergantung pada kualitas materi yang disampaikan, tetapi juga pada media pembelajaran yang digunakan. Buku pop-up berfungsi sebagai alat pendidikan yang menarik, menampilkan komponen tiga dimensi yang  dapat memberikan gerakan dan meningkatkan citra pada setiap halaman. Mata kuliah Anatomi dan Fisiologi Manusia merupakan komponen penting dari pendidikan kesehatan dan biasanya memerlukan representasi grafis yang menarik. Penelitian ini bertujuan untuk menganalisis pengaruh buku pop-up terhadap pemahaman mahasiswa. Desain penelitian ini menggunakan metodologi eksperimental murni dengan kerangka one-group pretest-posttest. Sampel penelitian yaitu mahasiswa Program Studi Farmasi Fakultas Kedokteran dan Ilmu Kesehatan Universitas Jambi, tahun akademik 2020/2021. Data yang dianalisis yaitu hasil tes yang telah diikuti sebelum dan setelah penggunaan buku pop-up. Jumlah seluruh nilai dibagi dengan jumlah mahasiswa menghasilkan rata-rata kelas. Kemampuan umum kelas dipastikan menggunakan nilai rata-rata ini. Kemudian ditentukan banyaknya mahasiswa yang belum mencapai target keberhasilan belajar dan persentase mahasiswa yang mencapainya. Hasil penelitian menunjukkan bahwa media buku pop-up dapat digunakan sebagai media pembelajaran untuk meningkatkan prestasi belajar mahasiswa dalam proses pembelajaran mata kuliah Anatomi dan Fisiologi Manusia.
Green synthesis nanoperak menggunakan ekstrak batang dadap serep (Erythrina Subumbrans (Hassk.) Merr) Maharini, Indri; Fitrianingsih, Fitrianingsih; Utami, Diah Tri
Journal of Pharmaceutical and Sciences Suppl. 1, No. 1 (2023)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v6i5-si.410

Abstract

Dadap serep stems contain secondary metabolite compounds of flavonoids, saponins, isoflavonoids, alkaloids and lectins which can act as reducing agents in the biosynthesis of nanosilver. This research aims to determine the effect of the concentration of liquid extract of dadap serep stem on the green synthesis silver nanoparticle (AgNPs) process. The aqueous extract of dadap serep stem reacted with one mM AgNO3 in a ratio of volume 1: 1 (FI), 1: 2 (FII), and 2: 1 (FIII). Characterization of AgNPs includes Surface Plasmon resonance (SPR) using UV/Vis spectrophotometer at wavelengths of 300-700 nm, particle size, and zeta potential using a particle size analyzer (PSA). The result showed that the SPR of AgNP values is 429-436 nm. AgNPs FI, II, and III particle sizes were 66.13 nm, 75.76 nm, and 75.96 nm, respectively. The PDI values below 0.5 confirmed that the distribution of nanoparticles was uniform. The most stable nanoparticle is Formula I.
Uji toksisitas buah palem merah (Cyrtostachys renda Blume.) menggunakan metode brine shrimp lethality test (BSLT) method Syamsurizal, Syamsurizal; Utami, Diah Tri; Sutrisno, Sutrisno; Efrini, Emi; Jumardi, Muhammad Ikhsan
Journal of Pharmaceutical and Sciences Suppl. 1, No. 1 (2023)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v6i5-si.429

Abstract

The red palm plant (Cyrtostachys renda) is a species of the Areca genus that grows widely in Jambi Province, making it an affordable plant to research for its medicinal properties. The Brine Shrimp Lethality Test (BSLT) is a toxicity test to screen for anticancer bioactive substances, with the test subject being Artemia salina Leach larvae, which are highly sensitive when exposed to toxic substances. The fruit and roots of C. renda were extracted using the maceration method by using a methanol solvent and partitioning using n-hexane, dichloromethane, ethyl acetate, and water. Based on the extract toxicity evaluation results, all extracts were toxic. Meanwhile, C.renda root dichloromethane extract had the highest toxic properties, with an LC50 value of 43.42 ± 0.659 ppm. However, the positive control's toxicity, potassium dichromate, was more toxic, with an LC50 value of 29.93 ± 0.668 ppm. The dichloromethane extract of C. renda roots can potentially be a poisonous agent. Further toxicity tests on cancer cells need to be carried out to be developed as an anticancer agent.
Formulasi body scrub dari kombinasi temu putih (Curcuma zedoaria) dan biji kurma (Phoenix dactylifera) Yuliawati, Yuliawati; Elisma, Elisma; Utami, Diah Tri; Pratiwi, Puspa Dwi
Journal of Pharmaceutical and Sciences Suppl. 1, No. 1 (2023)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v6i5-si.456

Abstract

Body scrub is a cosmetic form that removes dead skin cells caused by free radicals from various pollutants and ultraviolet (UV) radiation so skin cells become more accessible to regenerate. White turmeric (Curcuma zedoaria) and date seeds (Phoenix dactylifera) are plants that contain bioactive compounds to maintain and nourish the skin and have antioxidant activity. Besides, date seeds also have the potential as exfoliating agents to facilitate the release of dead skin cells. This study aimed to formulate a body scrub containing ethanol extract of white turmeric rhizome and date seed powder with five types of formulas (K+, K-, F1, F2, F3). This type of research is a true experimental, which includes the formulation and stability test. The stability test was conducted with the Cycling test method in 6 cycles (1 cycle for 2x24 hours) at temperatures of -4oC and 40oC and four months for stability at room temperature. Parameters observed include organolepticity, homogeneity, dispersibility, adhesion, pH, and viscosity. The results showed that this body scrub did not show any change in the organoleptic character, homogeneity, spreadability, adhesion, or pH values that met the requirements of a body scrub preparation. Viscosity met the requirement for stability test for room temperature in four months. This study concludes that the combination of ethanol extract of white turmeric rhizome and date seed powder seeds can be formulated to be a body scrub dosage form.
Antimicrobial Activity of Dadap Serep (Erythrina subumbrans (Hassk.) Merr.) Leaves Extract Utami, Diah Tri
Journal of Chemical Natural Resources Vol. 1 No. 1 (2019): Journal of Chemical Natural Resources
Publisher : Talenta Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (631.116 KB) | DOI: 10.32734/jcnar.v1i1.834

Abstract

The leaves of Erythrina has been used in Indonesia as a remedy for rheumatism, stomach-ache, asthma, dysentery, contact dermatitis, eczema and skin infections. However, there have been limited phytochemical or biological studies on the leaves of E. subumbrans and there are not studies that align with its traditional medicinal uses. The aim of this study was to assess the antimicrobial activity of the leaves of E. subumbrans to support its topical use in the treatment of skin infections. Disc diffusion agar assays were used to determine the antimicrobial activities of ethanol extracts of the leaves of E. subumbrans.The ethanol extracts showed the most significant activity with MIC values of 0,5 µg/mL. against a sensitive strain of Staphylococcus epidermidis. Extract concentration of 0,5 mg/ml, 1 mg/ml, 5 mg/ml and 10 mg/ml showed inhibition zone continuously as high as 1,83 mm; 3,42 mm; 5,17 mm, and 8,00 mm. The ethanol extracts of the leaves of E. subumbrans also showed significant activity against Candida albicans with MIC values of 0,5 µg/mL. Extract concentration of 0,5 mg/ml, 1 mg/ml, 5 mg/ml and 10 mg/ml showed inhibition zone continuously as high as 4,00 mm; 4,17 mm; 5,25 mm, and 6,50 mm. Bioactive substance test showed that alkaloid, flavonoid, saponin, and triterpenoid were found in E. subumbrans extract indicates potential activity as antimicrobial agent. These results provide support for the customary (traditional and contemporary) use of E.subumbrans leaves for the treatment of nosocomial infections.
Co-Authors ., Elisma Efrini, Emi Elisma Elisma Fitrianingsih Fitrianingsih Halim, Rd Isa Ansori Jumardi, Muhammad Ikhsan Maharini, Indri Oka Lesmana, Oka Puspa Dwi Pratiwi Sumiadi, Sumiadi Sutrisno, Sutrisno Syamsurizal - - Very Dermawan Yuliawati