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All Journal Jurnal Riset Rumpun Ilmu Kedokteran (JURRIKE) Professional Evidence-based Research and Advances in Wellness and Treatment
Diah Retno Wahyuningrum
Unknown Affiliation
Health Professions Medicine & Pharmacology Nursing Public Health Veterinary

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Intervensi Nutrisi Neuroprotektif terhadap Kadar GFAP dan Skor NIHSS pada Pasien Stroke Iskemik Diah Retno Wahyuningrum; Kalasta Ayunda Putri; Fitni Hidayati; Fathia Rahmadini
JURNAL RISET RUMPUN ILMU KEDOKTERAN Vol. 4 No. 2 (2025): Agustus : Jurnal Riset Rumpun Ilmu Kedokteran
Publisher : Pusat riset dan Inovasi Nasional

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/jurrike.v4i2.6053

Abstract

Stroke is one of the leading causes of disability and mortality worldwide, with significant neurological and biochemical consequences. This study aimed to examine the effect of a neuroprotective nutritional intervention consisting of protein, phosphatidylcholine, phosphatidylserine, and inulin on glial fibrillary acidic protein (GFAP) levels and National Institutes of Health Stroke Scale (NIHSS) scores in acute ischemic stroke patients. The study employed a quasi-experimental design with a pretest-posttest control group, involving 18 patients divided equally into intervention and control groups. Data were collected at Dr. Kariadi General Hospital Semarang from January to February 2020, measuring serum GFAP levels using ELISA and assessing NIHSS scores before and after a seven-day intervention. The intervention group showed a significant decrease in GFAP levels and a more pronounced improvement in NIHSS scores compared to the control group. These findings suggest that the neuroprotective nutritional intervention may support both biochemical and clinical recovery in acute ischemic stroke patients. Implementing such nutritional strategies could complement standard care and enhance rehabilitation outcomes. Further research with larger sample sizes and longer follow-up is recommended to confirm these results and optimize the intervention protocol.  
The Relationship Between Spiritual Conditions and the Quality of Life of the Elderly in UPTD X Kalasta Ayunda Putri; Diah Retno Wahyuningrum
Professional Evidence-based Research and Advances in Wellness and Treatment Vol. 2 No. 1 (2025): January, 2025
Publisher : CV. Get Press Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.69855/perawat.v2i1.123

Abstract

Seniors experience various physical, psychological, and social changes that can impact their quality of life. One factor believed to improve their well-being is spirituality. Seniors with high spiritual levels tend to better face life’s challenges, show stronger psychological resilience, and have a higher quality of life. This study aims to examine the relationship between spiritual condition and quality of life among the elderly in UPTD X. An analytical observational design with a cross-sectional approach was used in this study. The sample consisted of 80 elderly individuals selected through Simple Random Sampling from a population of 100. Data were collected using the Daily Spiritual Experience Scale (DSES) questionnaire to measure spiritual condition and the Older People Quality of Life (OPQOL) questionnaire to assess the elderly’s quality of life. Data analysis was conducted using the Spearman Rho Correlation Test due to non-normal distribution. Results show that most seniors have a moderate to high spiritual condition. Those more active in spiritual activities tend to have a better quality of life than those with low spirituality. The correlation test revealed a significant relationship between spiritual condition and quality of life (r = 0.512, p = 0.001), indicating a medium-level correlation. The study concludes that better spiritual conditions lead to higher quality of life. To enhance elderly well-being in social institutions, interventions such as improving religious programs, providing better social support, and training health workers in spiritual guidance are essential.
Co-Authors Fathia Rahmadini Fitni Hidayati Kalasta Ayunda Putri