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All Journal Asian Journal of Healthcare Analytics Ophthalmologica Indonesiana
Syafridon, M Fadhil
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Chemistry Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health Veterinary

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RE-TRABECULECTOMY + 5-FLUOROURACIL IN PRIMARY ANGLE CLOSURE GLAUCOMA PATIENTS AGGRAVATED BY CONSUMPTION OF SCHIZOAFFECTIVE DRUG: Poster Presentation - Case Report - Resident Syafridon, M Fadhil; Fidalia; Sari, Prima Maya
Majalah Oftalmologi Indonesia Vol 49 No S2 (2023): Supplement Edition
Publisher : The Indonesian Ophthalmologists Association (IOA, Perhimpunan Dokter Spesialis Mata Indonesia (Perdami))

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35749/nykrk915

Abstract

Introduction : PACG occurs when the anterior chamber angle is occluded by the iris thus reducing aqueous humor outflow. Most schizoaffective patients use anticholinergic drugs which may result in iridocorneal angle closure through deposition. This article reported a Re-Trabeculectomy + 5 FU surgery in PACG which was aggravated by the use of schizoaffective drugs Case Illustration : A 43 year old woman, underwent Re-Trabeculectomy + 5 FU on LE after increasing IOP and regularly took schizoaffective drugs. Tapering of schizoaffective therapy was done 1 month preoperatively. Patient presented with LE UCVA of 3/60 and LE IOP is 30.9 mmHg with three anti- glaucoma medications. LE examinations revealed VH1 AC, bayonet sign and cupping on funduscope, closed angle on gonioscope, nasal step defect on humphrey and diffuse RNFL thinning on OCT. On the first postoperative day LE IOP is 18.5 mmHg. The schizoaffective therapy was re-initiated from psychiatric and evaluation was done weekly Discussion : Re-trabeculectomy surgery have been done considering the failure of the first trabeculectomy and administration of 5-Fluorouracil as an anti-fibrosis. The benefits of reducing preoperative dose of schizoaffective drugs for a month due to having an anticholinergic effect and reduces IOP by 5 mmHg. Psychiatrists and ophthalmologists work together to try to administer basic schizoaffective drug doses and evaluate IOP to keep it under control. Conclusion : The re-operative action was carried out by adding anti-fibrosis and cooperating with psychiatry for postoperative tapering of schizoaffective drugs. Long-term use of antidepressant drugs and benzodiazepines increases PACG.
Flank Versus Prone and Supine Positions in Percutaneous Nephrolithotomy: A Systematic Review of Stone Clearance and Perioperative Outcomes Yusuf, Yusuf; Zutianda, Wahyu; Syafridon, M Fadhil
Asian Journal of Healthcare Analytics Vol. 4 No. 2 (2025): November 2025
Publisher : PT FORMOSA CENDEKIA GLOBAL

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55927/ajha.v4i2.15669

Abstract

Percutaneous nephrolithotomy (PCNL) is traditionally performed in the prone position, though this may pose anesthetic risks for high-risk patients. The flank position has been proposed as an alternative, but evidence remains limited. This systematic review of seven studies (2008–2023) found that flank PCNL achieves stone-free rates of 85–91%, comparable to prone positioning, with similar complication profiles and indications of reduced bleeding and respiratory issues. Operative time varied across studies, while hospital stay remained consistent. Overall, the findings support flank PCNL as a safe and effective alternative, though small sample sizes and methodological heterogeneity highlight the need for larger multicenter research.
Co-Authors Fidalia Prima Maya Sari Yusuf Yusuf Zutianda, Wahyu