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Correlation Between Ocular Rigidity With Intraocular Pressure In Patient With Type 2 Diabetes Mellitus Roland Iqbal; Prima Maya Sari; Ramzi Amin; Fidalia
Sriwijaya Journal of Ophthalmology Vol. 2 No. 1 (2019): Sriwijaya Journal of Ophthalmology
Publisher : Department of Opthalmology, Faculty of Medicine, Universitas Sriwijaya

ABSTRACT Introduction and Objectives: Diabetes mellitus (DM) is known to have a biomechanical effect on tissue. High blood glucose concentrations that lead to increased production of free radical intermediates causes ocular rigidity (OR) changes. This change can effect intraocular pressure (IOP) in patients with type 2 DM. This study to determine correlation between ocular rigidity with IOP in patients with type 2 DM. Methods: A cross-sectional study with a correlation test design of OR with IOP in type 2 DM patients was conducted in RSUP dr. Mohammad Hoesin Palembang from January until June 2018. Eighty eye samples consist of 60 type 2 DM and 20 control group. IOP examination was performed using a Goldmann applanation tonometer and OR measurements using schiotz tonometer with two loads then assessed in Friedenwald differential tables. Result: There was a significant correlation between diabetic retinopathy and OR (p=0,000). There was a significant correlation between OR and IOP in NPDR and PDR group (p=0,000). There was a significant relationship between patient age with OR and IOP (p<0,05). Conclusion: There is a significant correlation between ocular rigidity and IOP in people with type 2 DM.

Characteristics of Primary Glaucoma in Glaucoma Clinic of Dr. Mohammad Hoesin General Hospital, Palembang Prima Maya Sari; Rizka Yunanda
Sriwijaya Journal of Ophthalmology Vol. 5 No. 1 (2022): Sriwijaya Journal of Ophthalmology
Publisher : Department of Opthalmology, Faculty of Medicine, Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/sjo.v5i1.75

Introduction: Glaucoma is the second leading cause of blindness for over 70 million people worldwide. Bilateral blindness occurs with an estimated 10%. In Indonesia, the prevalence of glaucoma is 0,46%. That means that 4 to 5 out of 1.000 people suffer from glaucoma. Considering glaucoma as the second cause of blindness after cataracts in the world and its irreversible nature, this study was conducted to determine the characteristics of patients with primary glaucoma in the Glaucoma Clinic, Dr. Mohammad Hoesin General Hospital in 2021 based on age, gender, diagnosis, and intraocular pressure. Methods: This research is a descriptive retrospective study using secondary data through the medical record of patients in the Glaucoma Clinic, Dr. Mohammad Hoesin General Hospital Palembang from January to December 2021. The sample of this study was 20 people, and there were 40 eyes diagnosed with primary glaucoma. Results: The number of Primary Glaucoma patients was more in female patients, namely 11 patients (55,0%) with age varies at ≤ 50 years of age (45,0%), namely 51-60 patients (35,0%) and aged ≥ 61 years as many as 4 patients (25%), with an age range from 40 years to 70 years. Most patients were POAG (85%), with the highest eye pressure was 38,8mmHg, and 43,4 mmHg in PACG. Conclusion: There were 20 cases of primary glaucoma at the Glaucoma Clinic of Dr. Mohammad Hoesin General Hospital Palembang in 2021 with 40 affected eyes. Most patients were female, with most age group <50 years, and the most common type of glaucoma was open-angle.

Relationship between Progressive Cup Disc Ratio and Intraocular Pressure in Primary Open Angle Glaucoma After 2 Antiglaucoma Agents for 3 Months M Fadhil Syafridon; Fidalia; Prima Maya Sari
Sriwijaya Journal of Ophthalmology Vol. 5 No. 2 (2022): Sriwijaya Journal of Ophthalmology
Publisher : Department of Opthalmology, Faculty of Medicine, Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/sjo.v6i1.77

Introduction: Primary open-angle glaucoma (POAG) is a subset of glaucoma defined by an open, normal-appearing anterior chamber angle and raised intraocular pressure (IOP) with no other underlying disease. Globally 57.5 million people were affected by primary open-angle glaucoma (POAG) in 2015, rising to 65.5 million by 2020. POAG can further lead to optic nerve damage, which can cause total blindness. POAG cannot be cured but can be controlled with medical therapy, laser, and surgical procedures. Antiglaucoma drugs are a method of treatment that can overcome this disease. This study aims to determine the characteristics of patients with POAG and progressivity of cup to disc ratio and intraocular pressure after 3 months of management of 2 antiglaucoma agents in POAG patients in Dr. Mohammad Hoesin General Hospital Palembang. Methods: This study retrospectively reviewed the medical records specific to primary open-angle glaucoma. Data was obtained from the patient register book recorded from February 2022 to May 2022 in Dr. Mohammad Hoesin General Hospital Palembang. The parameters analyzed were patients' profiles, namely gender, intraocular pressure, and cup to disc ratio before and after 3 months of combination 2 antiglaucoma agents. Timolol and latanoprost are the 2 antiglaucoma agents given to patients diagnosed of previous POAG (by an ophthalmologist). Results: From 30 patients diagnosed with POAG by an ophthalmologist, the number of primary open-angle glaucoma patients was more female, namely 19 patients (63.3%) than 11 male patients (36.7%), with a ratio of 1.28:1 between women and men. The cup to disc ratio between before and after 3 months of therapy using timolol and latanoprost was 0.628 ± 0.04 before therapy to 0.645 ± 0.06 after therapy (p<0.05). Intraocular pressure before and after 3 months of therapy was 24.76 ± 2.63 before therapy to 17.75 ± 2.08 (p<0,05). Both cup to disc ratio and intraocular pressure differs statistically from before and after therapy. Conclusion: Fixed combination therapy of timolol and latanoprost is effective in lowering intraocular pressure and reducing cup to disc ratio progressivity in patients with primary open-angle glaucoma.

PUBLIC EDUCATION ABOUT EYES DURING THE COVID-19 PANDEMIC Ramzi Amin; Petty Purwanita; Prima Maya Sari
Conferences of Medical Sciences Dies Natalis Vol. 3 No. 1 (2021): Conference of Medical Sciences Dies Natalis Faculty of Medicine Universitas Sri
Publisher : Fakultas Kedokteran Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (263.338 KB)

In December 2019, a case of pneumonia of unknown etiology first reported in Wuhan, Hubei Province, China. (1) The etiology was finally identified and showed a new type of coronavirus, which was given the tentative name 2019 novel coronavirus (2019-nCoV). On February 11, 2020, the World Health Organization (WHO) announced the name of the new virus, namely Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2), and the name of the disease as Coronavirus Disease (COVID-19).Indonesia reported its first two confirmed cases of COVID-19 inMarch 2, 2020. As of September 8, 2020, the number of confirmed cases of COVID-19 in Indonesia was 200,035, with 8,230 deaths (CFR 6.9%).

FILTRATION SURGERY OF TRABECTULECTOMIES WITH 5 – FLUOROURACIL IN ADVANCED POAG: Poster Presentation - Case Report - Resident Fadillah Amrina; Fidalia; Prima Maya Sari
Majalah Oftalmologi Indonesia Vol 49 No S2 (2023): Supplement Edition
Publisher : The Indonesian Ophthalmologists Association (IOA, Perhimpunan Dokter Spesialis Mata Indonesia (Perdami))

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35749/8c2cqp88

Introduction : Advanced Glaucoma (AG) is total cupping of optic nerve with or without severe visual field loss. The prevalence of AG in POAG, shows that 15% have a substantial visual field defect. Initial therapy for AG can use medications, surgical therapy is performed when adecuate medical treatment isn’t effective. Filtration surgery such as trabeculectomy and implantation of tube shunts can be performed. This case reports aims to understand the used of trabeculectomy+5FU in Advanced POAG. Case Illustration : A 55 years old woman came with blurry and tunnel vision accompanied by headache since 2 years ago. She got treatment yet stopped to control. Vision has progressively reduced since 2 months ago. Visual acuity OD 1/300 OS 1/60, IOP OD 25.1 mmHg and OS 29.8 mmHg with 4 drugs, cloudy lens, cupping, c/d ratio 0.9, nasalization, bayonet sign and peripapillary atrophy. The patient was diagnosed with Advanced POAG with immature senile cataract ODS. Patient was treated with trabeculectomy+5-FU due to uncontrolled IOP despite receiving adecuate therapy. Releasing sutures were used to control IOP after surgery. After surgery, the last IOP OS 12.6 mmHg, and bleb formed E1H1V0. Discussion : Conclusion : Patients was treated with trabeculectomy+5-FU, can control IOP stably in advance of POAG without serious complications, cost less than routine drugs and maintain visual function and improve quality of life. Filtration surgery such as trabeculectomy with AF agents is proven to reduce IOP more stably in advance of POAG.

RE-TRABECULECTOMY + 5-FLUOROURACIL IN PRIMARY ANGLE CLOSURE GLAUCOMA PATIENTS AGGRAVATED BY CONSUMPTION OF SCHIZOAFFECTIVE DRUG: Poster Presentation - Case Report - Resident M Fadhil Syafridon; Fidalia; Prima Maya Sari
Majalah Oftalmologi Indonesia Vol 49 No S2 (2023): Supplement Edition
Publisher : The Indonesian Ophthalmologists Association (IOA, Perhimpunan Dokter Spesialis Mata Indonesia (Perdami))

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35749/nykrk915

Introduction : PACG occurs when the anterior chamber angle is occluded by the iris thus reducing aqueous humor outflow. Most schizoaffective patients use anticholinergic drugs which may result in iridocorneal angle closure through deposition. This article reported a Re-Trabeculectomy + 5 FU surgery in PACG which was aggravated by the use of schizoaffective drugs Case Illustration : A 43 year old woman, underwent Re-Trabeculectomy + 5 FU on LE after increasing IOP and regularly took schizoaffective drugs. Tapering of schizoaffective therapy was done 1 month preoperatively. Patient presented with LE UCVA of 3/60 and LE IOP is 30.9 mmHg with three anti- glaucoma medications. LE examinations revealed VH1 AC, bayonet sign and cupping on funduscope, closed angle on gonioscope, nasal step defect on humphrey and diffuse RNFL thinning on OCT. On the first postoperative day LE IOP is 18.5 mmHg. The schizoaffective therapy was re-initiated from psychiatric and evaluation was done weekly Discussion : Re-trabeculectomy surgery have been done considering the failure of the first trabeculectomy and administration of 5-Fluorouracil as an anti-fibrosis. The benefits of reducing preoperative dose of schizoaffective drugs for a month due to having an anticholinergic effect and reduces IOP by 5 mmHg. Psychiatrists and ophthalmologists work together to try to administer basic schizoaffective drug doses and evaluate IOP to keep it under control. Conclusion : The re-operative action was carried out by adding anti-fibrosis and cooperating with psychiatry for postoperative tapering of schizoaffective drugs. Long-term use of antidepressant drugs and benzodiazepines increases PACG.

SCHWARTZ-MATSUO SYNDROME : AN IMPORTANT CAUSE OF SECONDARY GLAUCOMA : RARE CASE: Poster Presentation - Case Report - Resident Teguh Ridho Perkasa; Fidalia; Prima Maya Sari
Majalah Oftalmologi Indonesia Vol 49 No S2 (2023): Supplement Edition
Publisher : The Indonesian Ophthalmologists Association (IOA, Perhimpunan Dokter Spesialis Mata Indonesia (Perdami))

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35749/rkkb3g69

Introduction : Schwartz-Matsuo syndrome is a rare ocular condition characterized by rhegmatogenous retinal detachment, elevated intraocular pressure, and open anterior chamber angle with presence of aqueous cells. The prevalence of Schwartz-Matsuo syndrome is quite low and only reported through case studies. Case Illustration : A 63 years old female complained a visual aquity was no light perception on the left eye (LE) since 2 months ago. The symptoms are gradually getting worse, history of ocular trauma, recent surgery, photopsia, peripheral visual field loss were denied. Patient came to the hospital with IOP elevation on left eye. On Gonioscopy we interpretated as open angle chamber and USG examination we founded retinal detachment, Anti-glaucoma medication were given but no success to lower the IOP. Discussion : Typically, retinal detachment is associated with low IOP. In Schwartz-Matsuo syndrome the opposite is observed with elevated IOP. Hypothesized that photoreceptor outer segments pass through the retinal break allows for fluid and photoreceptor outer segments to gain access, enter the anterior chamber and block aqueous outflow at the level of the trabecular meshwork. A significant increase in IOP can lead to visual loss and blindness complicated by glaucoma requiring further medical or surgical intervention. Referred to this patient, she came with IOP elevation, open angle anterior chamber and retinal detachment that clinically diagnosed as Schwartz-Matsuo syndrome. Conclusion : Schwartz-Matsuo syndrome is primarily a clinical diagnosis; Early detection of disease and prompt management of increased IOP and retinal detachment is essential for a good outcome.

Virna Glaucoma Drainage Device Implantation On Pediatric Patient With Steroid Induced Glaucoma: Poster Presentation - Case Report - Resident CHRISTIAN ANDREW DARIAN SIANIPAR; Fidalia; Prima Maya Sari
Majalah Oftalmologi Indonesia Vol 49 No S2 (2023): Supplement Edition
Publisher : The Indonesian Ophthalmologists Association (IOA, Perhimpunan Dokter Spesialis Mata Indonesia (Perdami))

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35749/y1dyxh57

Introduction : Steroid-induced Glaucoma (SIG) in pediatric patient is reported to have a more progressive and severe manifestations often unresponsive to glaucoma filtration surgery. We aim to report a successful management of SIG using Virna implant on pediatric patient. Case Illustration : A 10 years old boy underwent bilateral Virna GDD implantation following uncontrollable IOP after multiple trabeculectomies. The patient presented with a UCVA of 4/60 on both eyes. IOP of RE and LE is 31.8 mmHg and 29.7 mmHg respectively with four anti-glaucoma medications. Both eyes revealed conjunctival hyperemia with no bleb formation, VH3 AC, 12 o’clock iridectomy, C/D ratio of 0.9 with bayonet sign and nasalization on indirect funduscope, open angle on gonioscope, annular scotoma on Humphrey, and diffuse thinning of RNFL on OCT. Six months postoperatively, BCVA of RE and LE is 6/60 and 6/30 respectively with minimal progression on both ocular visual field defects. As for IOP, RE IOP is 18.7 mmHg with two anti-glaucoma medications and LE IOP is 14.3 mmHg without anti-glaucoma medications. Discussion : Multiple failed trabeculectomies is an indication for GDD. Virna implants are meant for adult subsequently making plate and tube placement crucial in pediatric patient because the globe is still growing and relatively thin. It is necessary to evaluate IOP periodically after implantation as IOP will enter hypertensive phase and stabilize in 3-6 months. Conclusion : GDD implantation, including Virna Implant, is a viable alternative to children with refractory SIG to prevent further glaucomatous damage.

Upaya meningkatkan kesadaran masyarakat dalam menjaga kesehatan mata di masa pandemi Covid-19 Purwanita, Purwanita; Amin, Ramzi; Sari, Prima Maya; Anggraini, Rika; Rosataria, Defayudina Dafilianty; Salim, Muhammad Usman
Jurnal Pengabdian Masyarakat: Humanity and Medicine Vol 2 No 2 (2021): Jurnal Pengabdian Masyarakat: Humanity and Medicine
Publisher : Fakultas Kedokteran Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32539/Hummed.V2I2.58

The SARS-CoV-2 virus is part of the coronavirus family. Currently, transmission of SARS-CoV-2 through droplet that come out when coughing, sneezing or contact is believed to be the main route of transmission of the virus. Eye involvement in cases of COVID-19 has been reported in several journals. Research in Hubei, China, reported that 12 out of 30 confirmed COVID-19 patients were accompanied by conjunctivitis. One of the COVID-19 positive patients with conjunctivitis in Italy detected SARS-CoV-2 RNA in an eye specimen which may be a potential source of infection. Several studies have emphasized that the eyes are a potential entry point for the virus and emphasize the importance of masks and eye protection. Until now, there is no vaccine or specific treatment to deal with COVID-19, so prevention is the best step to take. Lack of public knowledge in recognizing how the SARS-CoV-2 virus is transmitted so that they are less introspective and do not take precautions for virus infection. Educational videos regarding things that must be considered about the eyes during the COVID-19 pandemic can be a means of health promotion to prevent the spread of infection. This community service is expected to attract the attention of the public to get to know COVID-19 and increase public awareness of how much we should work together to reduce the transmission of this virus.

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