This research aims to improve low student learning achievement, which is attributed to the lack of engaging teaching materials in both face-to-face and independent learning processes. To address this issue, the researcher developed an interactive e-module containing materials, images, videos, and quizzes, hoping to enhance the learning achievement of fourth-grade students at SD Muhammadiyah Ambarbinangun in IPAS (Science, Social Studies, and Culture) subjects. This study is a research and development (R&D) project, utilizing the five-step ADDIE development model: 1) analyze, 2) design, 3) development, 4) implementation, and 5) evaluation. Data collection techniques included interviews, observations, questionnaires, and tests. Test data were analyzed using normality, homogeneity, and paired-sample t-tests. Questionnaire data were analyzed using a Likert scale. This research produced teaching materials in the form of the CERFOSIS E-module for ifourth-grade IPAS at SD Muhammadiyah Ambarbinangun, focusing on the "Photosynthesis" topic. This e-module incorporates materials, images, videos, and quizzes. Based on the validation by media experts, the e-module received an average score of 4.4, categorized as "very good." Validation by subject matter experts (fourth-grade teachers) yielded an average score of 5, also categorized as "very good." These validation results indicate that the teaching material product is suitable for student trials. The results of the extensive trial showed that student questionnaires yielded an average score of 4.8, categorized as "very good." Teacher response questionnaires resulted in an average score of 4.3, also categorized as "very good." Furthermore, student test scores increased from an average of 75.42 to 83.75. Therefore, the CERFOSIS E-module teaching material for fourth-grade IPAS at SD Muhammadiyah Ambarbinangun, on the "Photosynthesis" topic, developed by the researcher, is deemed suitable for use in the learning process.