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All Journal Jurnal Penelitian Pendidikan IPA (JPPIPA) Jurnal Locus Penelitian dan Pengabdian
Lubis, Anisa Taqwa
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Aerospace Engineering Agriculture, Biological Sciences & Forestry Automotive Engineering Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Decision Sciences, Operations Research & Management Education Electrical & Electronics Engineering Materials Science & Nanotechnology Mathematics Physics

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Cerebral Histopathology in Acute Toxicity Test of Curcuma Zedoria Lubis, Adhayani; Wardhani, Fiska Maya; Lubis, Anisa Taqwa; Tandanu , Erny
Jurnal Penelitian Pendidikan IPA Vol 9 No 10 (2023): October
Publisher : Postgraduate, University of Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jppipa.v9i10.5482

Abstract

This research aims to determine the effect of the acute toxicity test of white turmeric extract (Curcuma zedoaria) on the brain organ. This research is experimental research with a Post Test Only Control Group Design. This research was conducted at the Pharmacy and Histology Laboratory. Faculty of Medicine. University of North Sumatra. The research was carried out from January to March 2023. The population in this research involved male white rats (Rattus norvegicus). The results of the acute toxicity test of white turmeric extract for 14 days showed no signs of toxicity or death in rats given the smallest to largest doses, resulting in an apparent LD50 value of white turmeric extract is >2 g/kgBW, and is classified in the practically non-toxic category. Rats that received white turmeric extract showed movement or activity, appearing more energetic by the end of the second week with increasing doses. Histopathological examination of the brain in the acute toxicity test revealed minimal changes, such as edema and congestion in line with increasing doses.
The Effectiveness of Clean and Healthy Lifestyle Behavior Education in Preventing Scabies among Children at the Medan Juvenile Correctional Institution Lubis, Anisa Taqwa; Ginting, Chrismis Novalinda; Nasution, Sri Wahyuni
Jurnal Locus Penelitian dan Pengabdian Vol. 5 No. 4 (2026): JURNAL LOCUS: Penelitian dan Pengabdian
Publisher : Riviera Publishing

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58344/locus.v5i4.5743

Abstract

Scabies is a contagious skin disease that remains a public health problem, particularly among children living in communal settings with high population density, such as Juvenile Correctional Institutions (Lembaga Pembinaan Khusus Anak/LPKA). Clean and Healthy Living Behavior (Perilaku Hidup Bersih dan Sehat/PHBS) plays an important role in preventing the transmission of scabies through changes in individual behavior. This study aimed to analyze the effectiveness of a community health promotive intervention through PHBS education in preventing scabies among children at LPKA Class I Medan. This study employed a quasi-experimental design with a pre-test and post-test group design. The research sample consisted of all 125 children residing at LPKA Class I Medan, selected using total sampling technique. The intervention comprised PHBS education delivered using PowerPoint presentation media. Data were collected before and after the intervention using a structured questionnaire assessing knowledge, attitudes, and practices related to PHBS for scabies prevention. Data analysis was performed using univariate and bivariate analyses, with the Wilcoxon Signed Rank Test applied due to non-normal data distribution. The results showed a significant increase in respondents’ knowledge and attitudes following the PHBS educational intervention (p < 0.001), as well as a significant improvement in scabies prevention practices (p = 0.010). The greatest improvement was observed in the knowledge aspect, while changes in practice were relatively lower, possibly influenced by limitations in facilities and environmental conditions within the LPKA.
Co-Authors Ginting, Chrismis Novalinda Lubis, Adhayani Tandanu , Erny Wardhani, Fiska Maya