Nugrahaningsih WH
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Journal : Life Science

Analisis Kadar Kalsium pada Batita Stunting Kota Semarang: Analysis of Calcium Levels in Stunted Toddlers in Semarang City Rochly, Revinta Nur Aulia; Ari Yuniastuti; Lisdiana; Nugrahaningsih WH
Life Science Vol. 14 No. 2 (2025): November 2025
Publisher : Universitas Negeri Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15294/unnesjlifesci.v14.i2.12044

Abstract

Calcium (Ca) is a type of micronutrient that is important for children, especially during toddlerhood (children under three years of age), in their growth and development, where if the body lacks Ca, the bone mineralization process will be low and result in low mineralization of the matrix of new bone deposits, affecting the work of osteoblasts. As a result, children's linear growth will be hampered, and there is a risk of stunting. The research objective is to analyze calcium levels in stunted toddlers aged between 6-36 months in Semarang City. This research is an analytical observational study with a cross-sectional research design carried out in Bandarharjo and Tanjungmas sub-districts. The research sample consisted of 20 stunting toddlers and 20 non-stunting (normal) toddlers with an age range of 6-36 months. The independent variable in this study itself is blood calcium levels. The statistical analysis used was the Mann-Whitney U test. The results revealed that Ca levels in stunted toddlers were 9.95 mg/dL, meanwhile for normal toddlers, it is 16.51 mg/dL. Statistically, it shows that calcium levels in stunted toddlers are significantly different from those in normal toddlers (p = 0.000). In conclusion, there is a statistically significant difference in Ca levels between stunted and normal toddlers aged 6–36 months in Semarang City. The findings suggest that Ca status constitutes an important nutritional factor to be addressed in efforts to prevent stunting among toddlers.
The Effect of Tamarind Fruit Nanoparticles (Tamarindus indica) on the Sperm Quality of Hyperglycemic Rats Bagus Hammam Falah; Wulan Christijanti; Nugrahaningsih WH; R. Susanti
Life Science Vol. 14 No. 2 (2025): November 2025
Publisher : Universitas Negeri Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15294/unnesjlifesci.v14.i2.24064

Abstract

Hyperglycemia is an increase in glucose levels in the blood. This condition can trigger glucose autooxidation which can produce free radicals. Free radicals can cause damage to male reproductive organs and quality. Tamarind fruit has a high flavonoid which has the potential as an antioxidant. This study aims to analyze the effect of tamarind fruit nanoparticles on spermatozoa quality in hyperglycemic rats. This study is experimental with Post-Test Control Group Design. A sample of 15 male Wistar rats were induced by alloxan and then divided into three groups, namely the control group, tamarind fruit nanoparticles with a dose of 30 mg/KgBB (NP1) and 60 mg/KgBB (NP2) for 28 days. Sperm quality was observed with parameters of concentration, motility and viability. The data were analyzed using One Way ANOVA and LSD. The results of the Anova test showed that tamarind nanoparticle treatment could significantly improve sperm quality (P<0.05). The LSD test showed that the concentration, motility and viability of sperm in group (K) were significantly different from groups NP1 and NP2. The highest to lowest average sperm concentration in sequence was in groups NP2 (49.60x106±6.06x106), NP1 (41.60x106±7.40x106) and K (20.80x106±7.56x106). The highest to lowest average percentage of sperm motility in sequence was in groups NP2 (82.20±9.75), NP1 (74.00±4.74), K (47.20±10.66). The highest to lowest average percentage of sperm viability in sequence was in the NP2 group (76.80±4.49), NP1 (72.20±7.12), K (31.60±7.89). The conclusion of this study is that tamarind nanoparticles have an effect on improving sperm quality in hyperglycemic rats.