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All Journal Nusantara Medical Science Journal Jurnal Keperawatan dan Kesehatan (JKK)
Hartungi, Florean
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Health Professions Materials Science & Nanotechnology Medicine & Pharmacology Neuroscience Nursing Public Health

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Thyroglossal Duct Cyst: Clinical Insights from a Case Report Christeven, Robert; Hartungi, Florean
Nusantara Medical Science Journal Vol. 10 No. 1 (2025): Volume 10 Issue 1, January - June 2025
Publisher : Faculty of Medicine, Hasanuddin University.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20956/nmsj.v10i1.48026

Abstract

Introduction and importance: A thyroglossal duct cyst (TGDC) is the most common congenital mass found in the neck region. TGDC originates from the thyroglossal duct and persists along the descending groove of the thyroid gland, from the foramen caecum to the superior thyroid gland in front of the trachea. Presentation of case: A 46-year-old man presented with a slowly enlarging lump at the anterior midline of the neck, first noticed about 10 years earlier. On examination, a well-defined, round, cystic mass measuring 3.5 × 3.3 cm was found superior to the thyroid cartilage. The mass moved with tongue protrusion and swallowing and was mobile, painless, and non-tender. These findings were consistent with a thyroglossal duct cyst. Discussion: Thyroglossal duct cyst (TGDC) is a congenital midline neck mass resulting from the persistence of the thyroglossal duct during thyroid descent. Diagnosis is based on clinical features and imaging, with the Sistrunk procedure serving as the gold standard treatment to prevent recurrence. The patient underwent successful surgical excision without complications, and histopathology confirmed the diagnosis. Conclusions: The Sistrunk's Procedure surgery was conducted successfully with no postoperative complication in this case.
WHEN CHRONIC HEPATITIS B TURNS ACUTE: UNDERSTANDING AND MANAGING FLARES Hartungi, Florean; Christeven, Robert
Jurnal Keperawatan dan Kesehatan Vol 16 No 2 (2025): Jurnal Keperawatan dan Kesehatan
Publisher : Sekolah Tinggi Ilmu Keperawatan Muhammadiyah Pontianak

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.54630/jk2.v16i2.616

Abstract

Hepatitis B flare is a sudden exacerbation of chronic hepatitis B, defined by an abrupt ALT rise >5× upper limit of normal. Clinically, it may resemble acute hepatitis B, but low IgM anti-HBc titers and high HBV DNA levels aid differentiation. Flares arise from immune-mediated hepatocyte injury, triggered spontaneously, by immunosuppressive or antiviral therapy, pregnancy, viral superinfection, or viral genotype variations. Presentation ranges from asymptomatic biochemical changes to severe hepatitis, coagulopathy, and acute liver failure. Evaluation requires thorough history, physical examination, laboratory testing, imaging, and sometimes liver biopsy. Management focuses on supportive care and early nucleos(t)ide analogue therapy, as interferon can precipitate hepatic decompensation in severe immune-driven flares. Prognosis depends on baseline liver health; patients without cirrhosis generally recover, while acute-on-chronic liver failure carries high short-term mortality and may necessitate liver transplantation. Prompt recognition and timely antiviral therapy are essential to prevent liver failure, highlighting the importance of individualized strategies for optimal outcomes in hepatitis B flares. Keyword: chronic hepatitis B, flare
Co-Authors Christeven, Robert