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All Journal Research of Scientia Naturalis
Azhar, Ardi Azhar
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Agriculture, Biological Sciences & Forestry Chemistry Physics

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Synthetic Biology-Driven Bioplastics: A Life Cycle Assessment and Environmental Impact Study Azhar, Ardi Azhar; Alves, Livia; Gomez, Raul
Research of Scientia Naturalis Vol. 2 No. 5 (2025)
Publisher : Yayasan Adra Karima Hubbi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70177/scientia.v2i5.2386

Abstract

The pervasive environmental pollution caused by petroleum-based plastics has catalyzed the search for sustainable alternatives. Bioplastics, derived from renewable biomass, offer a promising solution, yet their production can be inefficient and compete with food resources. Synthetic biology provides powerful tools to engineer microorganisms for the high-yield production of bioplastics like polyhydroxyalkanoates (PHA) from non-food feedstocks. This study aimed to conduct a comprehensive life cycle assessment (LCA) to quantify and compare the environmental impacts of PHA produced via a synthetically engineered microbial platform against conventional polyethylene terephthalate (PET). A "cradle-to-grave" LCA methodology was employed, encompassing feedstock cultivation, fermentation, polymer extraction, and end-of-life scenarios including landfilling and industrial composting. The results revealed that the synthetic biology-driven PHA exhibited a 65% lower global warming potential and a 70% reduction in non-renewable energy use compared to PET. However, it showed higher impacts in eutrophication and land use, linked to its lignocellulosic feedstock origins. The end-of-life analysis confirmed the significant advantage of PHA’s biodegradability. This study concludes that while synthetic biology-driven bioplastics offer substantial benefits in carbon footprint and fossil fuel dependency, a holistic view is crucial.  
Co-Authors Alves, Livia Gomez, Raul