<![CDATA[Chronic Rhinosinusitis (CRS) is an inflammatory condition affecting the nasal mucosa and paranasal sinuses that persists for 12 weeks or longer. This condition frequently leads to physical, emotional, and social impairments in patients. CRS can significantly impact quality of life, characterized by symptoms such as nasal congestion, facial pain or pressure, and impaired sense of smell. Proactive management is essential for CRS, and nasal irrigation with a 0.9% NaCl solution is considered a supportive therapy that may help alleviate the condition. This study aims to evaluate changes in quality of life based on scores from the Sinonasal Outcome Test-22 (SNOT-22), a questionnaire comprising 22 items, in CRS patients before and 10 days after undergoing nasal irrigation therapy with a 0.9% NaCl solution. The research was conducted as an analytical observational study using a cross-sectional approach, involving 36 adult patients (aged 18–60 years) diagnosed with CRS at Zainoel Abidin Regional General Hospital, Banda Aceh. Data were collected using the SNOT-22 questionnaire, administered both before and 10 days after nasal irrigation therapy. The study identified a higher prevalence of CRS in female patients compared to male patients and in the young adult age group (20–40 years), likely associated with hormonal factors and environmental exposure. Normality testing yielded a p-value > 0.05, indicating that the data were normally distributed. For normally distributed data, a paired t-test was applied to compare pre- and post-treatment scores. Statistical analysis revealed a significant difference between SNOT-22 scores before and 10 days after nasal irrigation therapy using a 0.9% NaCl solution (p-value < 0.05). The reduction in SNOT-22 scores reflects improvements in physical symptoms, such as nasal congestion and facial pain, as well as in the emotional and social well-being of patients.]]>
