Claim Missing Document
Check
Articles

Found 2 Documents
Search

Histopathological Transformation in Medullary Thyroid Carcinoma (MTC) with Poorly Differentiated Thyroid Carcinoma (PDTC) Jamnasi, Juli; Jonas A Bangun; Ronald T. H. Tambunan; Juli Yosa Mega; Paul S. Lumban Tobing; Tengku M. Fauzi
Majalah Ilmiah METHODA Vol. 15 No. 2 (2025): Majalah Ilmiah METHODA
Publisher : Universitas Methodist Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Medullary Thyroid Carcinoma (MTC) is a type of thyroid cancer originating from C cells, while Poorly Differentiated Thyroid Carcinoma (PDTC) is a more aggressive form with poor differentiation. The transformation between these two types can affect prognosis and treatment strategies. This study analyzes an 18-year-old female patient presenting with neck swelling and difficulty swallowing. The initial diagnosis of MTC was established through fine-needle aspiration biopsy (FNAB), and after surgical resection, histopathological analysis was conducted to evaluate any transformation to PDTC. Histopathological findings revealed MTC areas with high calcitonin-producing C cells. However, there were also areas exhibiting characteristics of PDTC, including increased mitotic activity, necrosis, and loss of calcitonin expression. This transformation indicates a shift from a more indolent cancer form to a more aggressive one. The transformation from MTC to PDTC in a young patient illustrates the value of careful monitoring and thorough histopathological evaluation. Appropriate management and understanding of these changes are crucial for improving treatment outcomes. Further studies are needed to elucidate the molecular mechanisms underlying this transformation.
Bakti Sosial Operasi Katarak dalam Meningkatkan Fungsi Penglihatan dan Produktivitas Masyarakat Kurang Mampu di Tebing Tinggi Sucipto, Sucipto; Anto, Endy Juli; Ronald T. H. Tambunan; Frengky S. Manullang; Widjaya Taufik Tiji; Tengku M. Fauzi; Jadeny Sinatra; Juli Jamnasi; Jekson Martiar Siahaan
Jurnal Pengabdian Pada Masyarakat METHABDI Vol 5 No 2 (2025): Jurnal Pengabdian Pada Masyarakat METHABDI
Publisher : Universitas Methodist Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Cataract is the leading cause of blindness worldwide and a major public health challenge, particularly among underserved populations in Indonesia. This community service activity aimed to restore vision and improve quality of life for underprivileged cataract patients through free cataract surgery provided by Lions Club Medan Angkasa and Lions Club Tebing Tinggi Royal in collaboration with Tebing Tinggi Police Department and Bhayangkara Hospital. The surgical camp was conducted on Sunday, April 27, 2025, at RS Bhayangkara Tebing Tinggi, in commemoration of the 79th Bhayangkara Anniversary. The activity included pre-operative screening, phacoemulsification cataract surgery, pterygium excision, and post-operative care. A total of 79 patients participated: 73 cataract cases and 6 pterygium cases. All surgeries were performed successfully by experienced ophthalmologists using modern surgical techniques. Post-operative evaluation showed significant visual improvement in 98% of patients. This initiative demonstrates the effectiveness of multi-sector collaboration in addressing preventable blindness and highlights the crucial role of community-based organizations in supporting healthcare access for marginalized populations.