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Arianto, F.
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Evaluation of Neutron Flux in Boron Neutron Capture Therapy for a 10-Year-Old Child with Head and Neck Rhabdomyosarcoma Using Monte Carlo Simulation Salim, F. M.; Hidayanto, E.; Setiabudi, W.; Arianto, F.
Atom Indonesia Vol 51, No 3 (2025): DECEMBER 2025
Publisher : National Research and Innovation Agency

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55981/aij.2025.1708

Abstract

Head and neck rhabdomyosarcoma is among the most frequently encountered malignancies in children under the age of 10, necessitating effective treatment modalities with minimal toxicity. Boron Neutron Capture Therapy (BNCT) is recognized as a promising therapeutic alternative in radiotherapy owing to its ability to selectively target malignant cells. The aim of this study was to evaluate the neutron beam quality of a BNCT collimator in a simulation model for the treatment of head and neck rhabdomyosarcoma in a 10-year-old pediatric phantom, using the MCNP 6.2 Monte Carlo method. The simulation included tumor modeling incorporating Gross Tumor Volume (GTV), Clinical Target Volume (CTV), and Planning Target Volume (PTV) to assess neutron flux distribution. The results showed a thermal neutron flux of 5.22 × 10⁹ n cm⁻² s⁻¹, an epithermal neutron flux of 1.22 × 10¹⁰ n cm⁻² s⁻¹, and a fast neutron flux of 5.91 × 10⁷ n cm⁻² s⁻¹. Further analysis indicated that the produced epithermal flux exceeded the minimum standard recommended by the IAEA, and the highest flux was concentrated in the GTV region, suggesting effective tumor targeting. However, the thermal-to-epithermal neutron flux ratio (0.43) remained above the threshold value recommended by the IAEA (≤ 0.05). In conclusion, while the collimator design was capable of delivering a high-quality epithermal neutron beam that selectively targeted the tumor, further optimization of the filter components remains necessary to reduce unwanted thermal flux and enhance therapeutic safety and efficacy.
Monte Carlo Simulation of Pediatric Chest Radiography: Validation of the Irradose Through Comparison with MCNP El Basraoui, O.; Qassimi, O.; Kabach, O.; Messous, M. Y.; Tahiri, N.; Arianto, F.; El Bounagui, O.
Atom Indonesia Vol 52, No 1 (2026): APRIL 2026
Publisher : National Research and Innovation Agency

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55981/aij.2026.1763

Abstract

Radiological examinations are essential for medical diagnostics, but accurate estimation of dose deposition is crucial for patient safety, particularly in pediatric patients. This study employs Monte Carlo simulations with the MCNP code and a newly developed custom program, Irradose, to analyze photon dose deposition in a cylindrical phantom representing the thorax of a 10-year-old child. Two tissue-equivalent compositions were modeled: water and a more realistic HCNO-based soft tissue mixture. Depth-dose distributions obtained with Irradose were compared to MCNP results. Both codes predicted a maximum dose at 2 cm depth, followed by exponential fall-off, with deviations remaining below 5% across the depth range. These results validate Irradose as a reliable and computationally efficient tool for pediatric chest dosimetry in phantom studies. While limited to simplified geometries, this work demonstrates the potential of Irradose for use in preliminary dose assessments and as a complement to established Monte Carlo codes.