Lisdiana Mardanus
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Effect of Stichopus Hermanni to Bigonial Width on Maxillary Suture Expansion using Cephalometric Analysis Kristin Gaby Rosari; Noengki Prameswari; Lisdiana Mardanus
Denta Journal Kedokteran Gigi Vol 11 No 2 (2017): Agustus
Publisher : Fakultas Kedokteran Gigi Universitas Hang Tuah

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Background:Maxillary expansion uses mechanical forces to open the maxillary suture which causes inflammation and bone remodeling around the area. Stichopus hermanni is known to contain flavonoid, chondroitin sulfate, and saponin which is used to inhibit inflammatory process, increase bone metabolism and mineralization, and wound healing. Purpose: The aim of this experiment is to know the effect of Stichopus hermanni to bigonial width on maxillary suture remodeling expansion using cephalometric analysis. Materials and Methods: Experimental units used were 24 male Cavia cobaya divided into 4 groups (n=6). Group K(-) is negative control. Helical spring was applied and activated in the other 3 groups for 10 days. Group K(+) was given 2% NaCMC gel, both group P1 and P2 was given 3% Stichopus hermanni gel. Group P2 were also given retention period for 10 days after activation period. Cavia cobaya were then decapitated and observed for the bigonial width changes. The data was analyzed with One Way ANOVA test continued with LSD test. Results: The result of ANOVA test showed siginficant differences among the treatment groups p=0,000 (p<0,05). LSD test showed significant differences between group K(-) and K(+) (Sig. 0,005), K(-) and P1 (Sig. 0,001), and group K(-) and P2 (Sig. 0,000). Conclusion: 3% Stichopus hermanni gel increases bigonial width but not significant in remodeling process on maxillary suture expansion.
The Effect of Propolis Extract To Increase Fibroblast In Remodeling Process at Tension Side of Orthodontic Tooth Movement Budi Handayani; Lisdiana Mardanus
Denta Journal Kedokteran Gigi Vol 11 No 1 (2017): Februari
Publisher : Fakultas Kedokteran Gigi Universitas Hang Tuah

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Background: Orthodontic treatment requires time so, duration of orthodontic treatment time needs to be shortened in various ways. Flavonoid is an active content of propolis, that might accelerate tissue regeneration. Flavonoid might increase the number of fibroblast at tension side of orthodontic tooth movement. Purpose: The purpose of this study was to examine the effect of propolis extract gel towards the number of fibroblasts at tension side to accelerate orthodontic tooth movement. Materials and Methods: Thirty male Cavia cobayas were divided into three groups. The first group, ( P) was given treatment to make orthodontic tooth movement and propolis extract gel. The second group, K(+) was given treatment and NaCMC gel. The third group, K(-) was served as control. After 14 days, the Cavia cobayas were sacrified. Fibroblast number was examined with light microscope 400 X. Result: Mean and SD in K(-):100 ± 13,2; K(+):80 ± 13,05; (P):176 ± 17,9. The result of ANOVA test showed significant increase in the number of fibroblasts. The LSD test showed significant result in all groups with significance result p ≤ 0,05. Conclusion: Propolis extract can increase fibroblast number to accelerate orthodontic tooth movement.