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All Journal Indonesia Natural Research Pharmaceutical Journal (INRPJ)
Gledys, Juliana
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Biochemistry, Genetics & Molecular Biology Chemistry Immunology & microbiology Medicine & Pharmacology

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LITERATURE REVIEW ANALYSIS OF ANTIOXIDANT ACTIVITY OF RED PIDADA LEAVES (Sonneratia Caseolaris L) USING A SPECTROPHOTOMETER Rahmah, Siti; Bii, Maria Febriani Wea; Permatasari, Nurfebby; Saputra, Juliansyah Yugis; Halitopo, Maria Ratu F.; Agustin, Tasya; Gledys, Juliana; Purnama, Maya
INDONESIA NATURAL RESEARCH PHARMACEUTICAL JOURNAL Vol 10, No 1 (2025)
Publisher : Fakultas Farmasi Universitas 17 Agustus 1945 Jakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52447/inrpj.v10i1.8875

Abstract

This study aimed to evaluate the antioxidant activity and toxicity of the ethanolic extract of red mangrove leaves (Sonneratia caseolaris). Extraction was conducted by maceration using 96% ethanol. Antioxidant activity was tested using the DPPH and ABTS methods with vitamin C as a reference, while toxicity was determined through the Brine Shrimp Lethality Test (BSLT). The extract showed very strong antioxidant activity with IC50 values of 37.67 ppm (ABTS) and 4.25 ± 3.05 ppm (DPPH). LC-HRMS identified TEMPO, Choline, and Betaine, with TEMPO showing the highest antioxidant potential. The BSLT result indicated non-toxic properties (LC50 >1500 ppm). The extract shows promise as a safe and effective natural antioxidant source.
Co-Authors Agustin, Tasya Bii, Maria Febriani Wea Halitopo, Maria Ratu F. Permatasari, Nurfebby Purnama, Maya Saputra, Juliansyah Yugis Siti Rahmah