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All Journal Advances in Tropical Biodiversity and Environmental Sciences
Ida Bagus Komang Ardana
Udayana University
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Earth & Planetary Sciences Environmental Science Immunology & microbiology Medicine & Pharmacology Veterinary Other

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The Impact of Concurrent Gleptoferron and Toltrazuril Injection on Hematological Profile, Health, and Growth in Pre-weaned Piglets Ida Bagus Komang Ardana; Anak Agung Gde Jayawardhita; Anak Agung Gde Oka Dharmayudha; Anak Agung Sagung Kendran
Advances in Tropical Biodiversity and Environmental Sciences Vol. 8 No. 3 (2024): October 2024: Pages 119-170
Publisher : Institute for Research and Community Services Udayana University (LP2M Universitas Udayana)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24843/ATBES.2024.v08.i03.p10

Abstract

This study sought to assess the effects of simultaneous Gleptoferron and Toltrazuril administration on hematological parameters, health status, and growth performance in pre-weaned piglets. A total of 54 piglets aged 1 to 3 days were randomly allocated into three groups: a control group receiving a placebo injection, a group administered iron (Ferdex), and a group injected with Gleptoferron in conjunction with Toltrazuril (Forceris). Hematological markers, morbidity, mortality, and body weight growth were evaluated during a 20-day duration. The findings indicated that the administration of Gleptoferron and Toltrazuril markedly elevated red blood cell (RBC) counts, hemoglobin concentrations, and hematocrit levels relative to the iron-only group, without an increase in total white blood cell (WBC) counts, suggesting the absence of post-injection infection. Moreover, pigs administered Forceris did not develop hypochromic anemia and had a reduced incidence of diarrhea (6.7%) with no mortality, indicating enhanced gut health and excellent coccidiosis prevention. Significantly, pigs administered Forceris exhibited a weight gain of 9 kg at 20 days of age, in contrast to 7.9 kg in the iron-only cohort. The results indicate that the simultaneous use of Gleptoferron and Toltrazuril provides more advantages in avoiding anemia, improving growth, and fostering better health outcomes in pre-weaned piglets than iron supplementation alone. This efficient and pragmatic approach has significant ramifications for enhancing production in pig breeding operations
Effect of Giving Sea Salt Through Drinking Water to Broilers on the Total Plate Count of Bacteria, Coliforms, and Escherichia coli in Broiler Feces Tifano Pratista Ramandika Nur Husodo; Ida Bagus Komang Ardana; I Made Merdana; I Gusti Ketut Suarjana
Advances in Tropical Biodiversity and Environmental Sciences Vol. 10 No. 1 (2026): February 2026
Publisher : Institute for Research and Community Services Udayana University (LP2M Universitas Udayana)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24843/ATBES.2026.v10.i01.p010

Abstract

The gastrointestinal microbiota plays an essential role in maintaining intestinal health, immune function, and productivity in broiler chickens. The growing concern about antimicrobial resistance arising from the prolonged use of antibiotic growth promoters has spurred exploration of natural alternatives to modulate gut microbial populations. Sea salt contains various minerals, including sodium, magnesium, potassium, and calcium, which may influence intestinal microbial ecology. This study aimed to evaluate the effect of sea salt supplementation through drinking water on the Total Aerobic Bacterial Count (TABC), Coliforms, and Escherichia coli populations in broiler feces. A total of 72 CP 707 broiler chickens were assigned to four treatment groups: control without sea salt supplementation (S0), 1 g/L sea salt (S1), 2 g/L sea salt (S2), and 4 g/L sea salt (S3). Fecal samples were collected by cloacal swabbing at 0, 15, and 30 days of age. Bacterial enumeration was performed using Nutrient Agar and Eosin Methylene Blue Agar. Data were analyzed using multivariate analysis of variance (MANOVA) followed by Duncan’s Multiple Range Test. The results showed that sea salt supplementation had no significant effect on TABC, Coliform, or E. coli counts (P>0.05). In contrast, broiler age significantly affected all bacterial parameters evaluated (P<0.05). Although lower bacterial counts were numerically observed in the 1 g/L and 2 g/L treatment groups compared with the control, these differences were not statistically significant. In conclusion, sea salt supplementation through drinking water at concentrations up to 4 g/L did not significantly reduce fecal bacterial populations in broiler chickens. Age-related microbial succession had a greater influence on bacterial dynamics than sea salt supplementation.
Co-Authors Anak Agung Gde Jayawardhita Anak Agung Gde Oka Dharmayudha Anak Agung Sagung Kendran I Gusti Ketut Suarjana I Made Merdana Tifano Pratista Ramandika Nur Husodo