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All Journal Journal of Innovative and Creativity
Baharuddin, Khanza Az-Zahra
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Education Languange, Linguistic, Communication & Media Mathematics Social Sciences Other

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Penyebab Anemia Pada SLE (Review Sistematic) Idrus, Rezwandi Idwar; Lamusu, Muhammad Hafizh Afriyad; Baharuddin, Khanza Az-Zahra; Faisal, Deva Najwa; Rizkah, Nur Miftahur; Mokoginta, Nelyan
Journal of Innovative and Creativity Vol. 5 No. 3 (2025)
Publisher : Fakultas Ilmu Pendidikan Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/joecy.v5i3.5982

Abstract

Systemic Lupus Erythematosus (SLE) is a multisystem autoimmune disease that is often accompanied by hematological complications, particularly anemia with a high prevalence. This study is a systematic review of journals published between 2019 and 2024 to describe the characteristics of anemia in SLE patients based on age, gender, type of anemia, and severity. Results indicate that anemia most commonly occurs in young adults (20–30 years old) and is more prevalent in women due to the high prevalence of SLE, although men tend to experience more severe disease. AIHA is the most characteristic and high-risk type of anemia, while ACD and IDA are more common in older age groups. The severity of anemia varies from mild to severe, with severe anemia mainly found in AIHA associated with high lupus activity. The most dangerous forms of anemia include AIHA accompanied by thrombotic microangiopathy (TMA) or hemophagocytic lymphohistiocytosis (HLH) because they can cause massive hemolysis and organ failure.
Co-Authors Faisal, Deva Najwa Idrus, Rezwandi Idwar Lamusu, Muhammad Hafizh Afriyad Mokoginta, Nelyan Rizkah, Nur Miftahur