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All Journal Nusantara Medical Science Journal Natural: Jurnal Pelaksanaan Pengabdian Bergerak Bersama Masyarakat Jurnal Sains dan Kesehatan
Husna, Firda Asma'ul
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Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemistry Economics, Econometrics & Finance Engineering Health Professions Immunology & microbiology Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Medicine & Pharmacology Neuroscience

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Maternal Obesity, Metabolic Syndrome, and Long-Term Effects on Offspring: A Developmental Origins of Health and Disease (DOHaD) Perspective Tsaqifah, Nabila Aulia; Hanifah, Rifdah; Husna, Firda Asma'ul; Hidayati, Mailani Dwi; Widyawati , Dwi; Putri, Ghea Farmaning Thias; Al Shadrina, Ainina
Nusantara Medical Science Journal Vol. 10 No. 2 (2025): Volume 10 Issue 2, July - December 2025
Publisher : Faculty of Medicine, Hasanuddin University.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20956/nmsj.v10i2.47907

Abstract

Introduction: The global prevalence of obesity among women of reproductive age has increased markedly over the past two decades, reaching 24% in high-income and 16% in low- and middle-income countries. This trend contributes to adverse maternal and neonatal outcomes, including a 2–4-fold higher risk of gestational diabetes, a threefold increase in preeclampsia, and up to a 50% higher caesarean delivery rate. Maternal metabolic disorders also have long-term consequences for offspring metabolic and cardiovascular health. Objective: To synthesize current biological and epidemiological evidence linking maternal metabolic status to offspring health within the Developmental Origins of Health and Disease (DOHaD) framework. Methods: A comprehensive search was conducted in PubMed, Scopus, and Web of Science from January 2015 to September 2025 using keywords related to maternal obesity, metabolic syndrome, DOHaD, offspring health, and epigenetics. Included studies comprised human and animal research with follow-up beyond two years, while case reports, editorials, and studies without long-term outcomes were excluded. Findings: From 22 eligible studies, consistent evidence indicates that maternal obesity and metabolic syndrome affect offspring through placental dysfunction, systemic inflammation, and epigenetic reprogramming. Offspring of obese mothers show a 1.5–2.8-fold increased risk of obesity and insulin resistance during adolescence and adulthood. Epigenome-wide analyses reveal altered methylation of genes regulating lipid metabolism (LEP, IGF2) and inflammatory pathways, supporting the DOHaD hypothesis. Conclusion: Maternal metabolic health critically shapes offspring developmental and metabolic outcomes. Preconception and antenatal interventions targeting metabolic optimization provide key opportunities to prevent intergenerational transmission of metabolic risk and promote healthier future generations.
Edukasi Enam langkah Mencuci Tangan di Sekolah Dasar Negeri Kamasan 2 Kabupaten Serang Banten Husna, Firda Asma'ul; Mutria Maharani; Miftahul Fauzan; Khaerunissa All Husna; Alika Nadina Nurazizah; Dhini Herliani; Daniya Putri Kurniawan; Dewi Ardianti; Abigail Cecilia Sihombing; Muhammad Fajar Mubarok; Muhammad Syafiqi Noor Rohmansyah; I'tollah I'tollah; Olga Handika; Ukroma Haekal; Siti Aisyah Rohamdhoni; Neisha Shaquila Nabila Kamil; Uswatun Hasanah; Ayesha Zivanka Anfasyah; Nabila Adawiyah; Alma Tsabitha Sasikirana
Natural: Jurnal Pelaksanaan Pengabdian Bergerak bersama Masyarakat. Vol. 4 No. 1 (2026): February: Natural: Jurnal Pelaksanaan Pengabdian Bergerak bersama Masyarakat
Publisher : Asosiasi Riset Ilmu Kesehatan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61132/natural.v4i1.2058

Abstract

Hand washing is a major pillar in clean and healthy living behaviors (PHBS). However, there are still children who do not understand the correct handwashing technique so that germ cleaning is not optimal. This community service activity aims to improve students' knowledge and motor skills in practicing the six steps of hand washing according to World Health Organization (WHO) standards. The method used in this activity is interactive counseling combined with live demonstrations. The stages of the activity include providing material through audiovisual media (video/poster), direct demonstrations by instructors, and independent practice by all participants. In addition, a question and answer session was held to ensure student understanding and corrective feedback on inappropriate movements. Evaluation instruments in the form of observation sheets were used to assess the accuracy of the sequence, duration, and coverage of the hand area when washing. The result of this activity was the success of all participants in practicing the six-step sequence of handwashing correctly independently. The involvement of teachers and school health workers also strengthens the sustainability of this practice through regular monitoring. Through this education, it is hoped that early awareness will arise which has become a routine habit to reduce the risk of disease transmission in the school and home environment and support the creation of a culture of clean living from an early age.
Profil Pengetahuan Data Kesehatan Dasar: Studi Deskriptif Mengenai Golongan Darah dan Hemoglobin pada Kelompok Usia Dewasa Muda: Basic Health Data Knowledge: A Descriptive Study of Blood Groups and Hemoglobin in Young Adults Husna, Firda Asma'ul; Hermawati, Luluk; Putri, Ghea Farmaning Thias; Pratiwisitha, Maytia
Jurnal Sains dan Kesehatan Vol. 8 No. 2 (2026): J. Sains Kes.
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25026/jsk.v8i2.2630

Abstract

Blood type and hemoglobin (Hb) levels constitute essential basic health data that play a critical role in health screening, emergency medical management, and individual readiness for blood donation. Among university students, the availability and understanding of these basic health data remain challenging due to suboptimal levels of knowledge and limited screening history. This study aimed to analyze students’ knowledge levels regarding blood type and hemoglobin levels as basic health data and to explore their implications for personal health awareness and potential participation as blood donors. This research employed a descriptive observational design with randome sampling involving 143 students. Data were collected using a questionnaire to assess students’ knowledge levels and screening history related to blood type and hemoglobin levels. The results showed that 28% of students were unaware of their blood type, while approximately 77% had never known their hemoglobin levels. These findings indicate limited knowledge and screening history of basic health data, rather than reflecting clinically low hemoglobin levels. Overall, approximately two-thirds of students were aware of their blood type. The low level of knowledge regarding blood type and particularly hemoglobin levels reflect insufficient health screening awareness among young adults. Inadequate monitoring of hemoglobin levels may result in undetected anemia, potentially affecting health status and academic performance. Furthermore, limited knowledge of these health parameters may reduce students’ readiness to serve as potential blood donors. The availability of students’ basic health data related to blood type and hemoglobin levels remains suboptimal, highlighting the need for continuous health education and routine health screening programs within the university setting. Keywords:          blood type; hemoglobin; knowledge; basic health data; university students   Golongan darah dan kadar hemoglobin (Hb) merupakan data kesehatan dasar yang berperan penting dalam skrining kesehatan, penanganan kegawatdaruratan medis, serta kesiapan individu sebagai pendonor darah. Pada kelompok mahasiswa, ketersediaan dan pemahaman terhadap data kesehatan dasar ini masih menjadi tantangan karena tingkat pengetahuan dan riwayat pemeriksaan yang belum optimal. Penelitian ini bertujuan untuk menganalisis tingkat pengetahuan mahasiswa mengenai golongan darah dan kadar hemoglobin sebagai data kesehatan dasar serta implikasinya terhadap kesadaran kesehatan pribadi dan potensi keterlibatan sebagai pendonor darah. Penelitian ini merupakan studi observasional deskriptif dengan random sampling yang melibatkan 143 mahasiswa Data dikumpulkan menggunakan kuesioner untuk menilai tingkat pengetahuan dan riwayat pemeriksaan golongan darah serta kadar hemoglobin. Sebanyak 28% mahasiswa belum mengetahui golongan darahnya, sementara sekitar 77% mahasiswa belum pernah mengetahui kadar hemoglobinnya. Temuan ini menunjukkan rendahnya pengetahuan dan riwayat pemeriksaan terhadap data kesehatan dasar, bukan mencerminkan kondisi klinis kadar hemoglobin yang rendah. Secara umum, sekitar dua pertiga mahasiswa telah mengetahui golongan darahnya. Rendahnya pengetahuan mahasiswa terhadap golongan darah dan terutama kadar hemoglobin mencerminkan rendahnya kesadaran skrining kesehatan pada kelompok usia dewasa muda. Kurangnya pemantauan kadar hemoglobin berpotensi menyebabkan kondisi anemia tidak terdeteksi serta berdampak pada kesehatan dan performa akademik. Selain itu, keterbatasan pengetahuan ini juga memengaruhi kesiapan mahasiswa sebagai calon pendonor darah. Ketersediaan data kesehatan dasar mahasiswa terkait golongan darah dan kadar hemoglobin masih belum optimal, sehingga diperlukan edukasi dan skrining kesehatan berkelanjutan di lingkungan perguruan tinggi. Kata Kunci:         golongan darah; hemoglobin; pengetahuan; data kesehatan dasar; mahasiswa  
Co-Authors Abigail Cecilia Sihombing Al Shadrina, Ainina Alika Nadina Nurazizah Alma Tsabitha Sasikirana Ayesha Zivanka Anfasyah Daniya Putri Kurniawan Dewi Ardianti Dhini Herliani Dwi Widyawati Ghea Farmaning Thias Putri Hidayati, Mailani Dwi I'tollah I'tollah Khaerunissa All Husna Luluk Hermawati Miftahul Fauzan Muhammad Fajar Mubarok Muhammad Syafiqi Noor Rohmansyah Mutria Maharani Nabila Adawiyah Neisha Shaquila Nabila Kamil Olga Handika Pratiwisitha, Maytia Rifdah Hanifah Siti Aisyah Rohamdhoni Ukroma Haekal USWATUN HASANAH