Introduction: Renal tuberculosis is one of the most common form of urogenital tuberculosis. Objective: This study aims to compare the outcomes of retroperitoneal laparoscopic nephrectomy (RLN) compared to other surgical approaches for treating renal tuberculosis. Material & Methods: A comprehensive search of the scientific literature was conducted using databases such as PubMed, Scopus, ScienceDirect, and Cochrane to identify randomized controlled trials (RCTs) as well as prospective and retrospective studies comparing the effectiveness of RLN with other treatments (transperitoneal laparoscopic nephrectomy and open surgery) in the management of renal tuberculosis. Data from the included studies were pooled and analyzed. Results: A total of 6 cohort studies were incorporated into this meta‐analysis. The overall RLN was associated with a significantly shorter length of stay (WMD: −1.92; 95% CI: −3.22, - 0.62; p = 0.004). The terms of operative duration (p = 0.56), blood loss (p = 0.59), and overall complications (p = 0.76) did not show any differences. The present meta-analysis has limitations that need to be considered. The limited number of research studies may have impacted the statistical findings, and all the studies included were observational, which may have resulted in bias. Blinding was not implemented, and there was high heterogeneity in some outcomes, which may have affected the accuracy of the results. Recalculating the mean and standard deviation could have introduced bias. Conclusion: RLN shows a potential advantage regarding the lower length of stay. Keywords: Urogenital tuberculosis, nephrectomy, laparoscopy.