<![CDATA[Intravenous (IV) infusion therapy is a critical medical procedure, yet manual monitoring increases the risk of complications such as air embolism and irregular infusion flow, particularly in resource-constrained environments. Although several automated infusion monitoring systems have been proposed, their high implementation cost limits practical adoption. This research develops a low-cost IoT-based infusion monitoring system capable of real-time anomaly detection using a multi-architecture machine learning approach. The proposed prototype integrates an ESP32 microcontroller with load cell (HX711) and optical (LM393) sensors to acquire time-series infusion data. Ten models from classical machine learning, deep learning, hybrid, and ensemble categories were evaluated using a dataset of 10,420 records under a unified experimental setup. The results show that XGBoost had a perfect recall (1.0000) and a strong PRAUC, while the LSTM Autoencoder had the highest F1-Score (0.9343) and precision (0.8934). The best overall performance came from hybrid and ensemble methods, with CNN–LSTM having an F1-Score of 0.89, a recall of 0.99, and a precision of 0.80. This means they would be great for clinics where being sensitive is very important. The research shows that using a low-cost IoT infrastructure with carefully chosen deep learning or ensemble models can help find problems in real time. A web dashboard explains how the technology operates and its capabilities. This study examines a cost-effective and easily scalable method to enhance infusion safety in hospitals with limited financial resources.]]>
