<![CDATA[Histological tissue processing remains the “gold standard” for determining patient therapy and prognosis. One of the stages of tissue processing is fixation. The types of fixative solutions used are 10% NBF and Bouin. The purpose of this study was to determine the histological features of mouse (Mus Musculus) liver tissue fixed using 10% NBF and Bouin solutions. This study used a descriptive method. The population in this study were mice. The research sample was mouse liver organs. The research stages began with mouse surgery, fixation with 10% NBF and Bouin, dehydration, clearing, embedding, blocking, cutting, and staining. The results of the histological features of mouse livers fixed using 10% NBF with a time variation of 4 hours obtained good quality preparations of 33.33% and poor quality of 66.67%. In 10% NBF with a time variation of 16 hours, good quality was obtained of 83.33% and poor quality of 16.67%. In liver tissue preparations of mice (Mus musculus) fixed using Bouin's 4-hour variation, 83.33% of good quality preparations were obtained and 16.67% of poor quality preparations. In Bouin's 16-hour variation, 33.33% of good quality preparations were obtained, 50.00% of poor quality preparations and 16.67% of poor quality preparations were obtained. Suggestions for further research on the microscopic appearance of tissue fixed using Bouin's solution and other solutions other than 10% NBF with samples other than mouse liver organs (Mus Musculus).]]>
