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Evaluation Antibacterial Activity of Rosary Pea (Abrus precatorius L.) Leaf Extract against the Growth of Staphylococcus aureus and Shigella sonnei Shari, Amalia; Syahfitri, Alda Bunga
Journal of Food and Pharmaceutical Sciences Article In Press 2026
Publisher : Integrated Research and Testing Laboratory (LPPT) Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jfps.24861

Abstract

Bacteria are major contributors to infectious diseases, including Staphylococcus aureus and Shigella sonnei. Although antibiotics remain the primary treatment, prolonged use can lead to antimicrobial resistance, highlighting the need for alternative agents capable of inhibiting pathogenic bacteria. Scientific validation of medicinal plants is crucial for complementing traditional knowledge in bioprospecting efforts. The Rosary pea (Abrus precatorius L.) is one such plant with potential antibacterial properties. This study evaluates the inhibitory activity of Abrus precatorius L. leaf ethanol extract against S. aureus and S. sonnei at concentrations of 3.125%, 6.25%, 12.5%, 25%, 50%, and 100%. The extract demonstrated optimal activity at 100%, exhibiting moderate inhibition against S. aureus and weak inhibition against S. sonnei. These findings underscore the potential of Abrus precatorius L as a source of antibacterial compounds and provide a foundation for developing improved formulations with enhanced antibacterial efficacy.
Evaluation Antibacterial Activity of Rosary Pea (Abrus precatorius L.) Leaf Extract against the Growth of Staphylococcus aureus and Shigella sonnei Shari, Amalia; Syahfitri, Alda Bunga
Journal of Food and Pharmaceutical Sciences Article In Press 2026
Publisher : Integrated Research and Testing Laboratory (LPPT) Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jfps.24861

Abstract

Bacteria are major contributors to infectious diseases, including Staphylococcus aureus and Shigella sonnei. Although antibiotics remain the primary treatment, prolonged use can lead to antimicrobial resistance, highlighting the need for alternative agents capable of inhibiting pathogenic bacteria. Scientific validation of medicinal plants is crucial for complementing traditional knowledge in bioprospecting efforts. The Rosary pea (Abrus precatorius L.) is one such plant with potential antibacterial properties. This study evaluates the inhibitory activity of Abrus precatorius L. leaf ethanol extract against S. aureus and S. sonnei at concentrations of 3.125%, 6.25%, 12.5%, 25%, 50%, and 100%. The extract demonstrated optimal activity at 100%, exhibiting moderate inhibition against S. aureus and weak inhibition against S. sonnei. These findings underscore the potential of Abrus precatorius L as a source of antibacterial compounds and provide a foundation for developing improved formulations with enhanced antibacterial efficacy.